Coccidioidomycosis
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Coccidioidomycosis
Coccidioidomycosis (, ), commonly known as cocci, Valley fever, as well as California fever, desert rheumatism, or San Joaquin Valley fever, is a mammalian fungal disease caused by ''Coccidioides immitis'' or ''Coccidioides posadasii''. Coccidioidomycosis is endemic in certain parts of the United States in Arizona, California, Nevada, New Mexico, Texas, Utah, and northern Mexico. ''C. immitis'' is a dimorphic saprophytic fungus that grows as a mycelium in the soil and produces a spherule form in the host organism. It resides in the soil in certain parts of the southwestern United States, most notably in California and Arizona. It is also commonly found in northern Mexico, and parts of Central and South America. ''C. immitis'' is dormant during long dry spells, then develops as a mold with long filaments that break off into airborne spores when it rains. The spores, known as arthroconidia, are swept into the air by disruption of the soil, such as during construction, farming, lo ...
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Coccidioides Immitis
''Coccidioides immitis'' is a pathogenic fungus that resides in the soil in certain parts of the southwestern United States, northern Mexico, and a few other areas in the Western Hemisphere. Epidemiology ''C. immitis'', along with its relative '' C. posadasii'', is most commonly seen in the desert regions of the southwestern United States, including certain areas of Arizona, California, New Mexico, Nevada, Texas, and Utah; and in Central and South America in Argentina, Brazil, Colombia, Guatemala, Honduras, Mexico, Nicaragua, Paraguay, and Venezuela. Precise location ''C. immitis'' is largely found in California, but also Baja California and Arizona, while ''C. posadasii'' is regularly found in Texas, northern Mexico and in Central and South America. Both ''C. immitis'' and ''C. posadasii'' are present in Arizona.Hospenthal, Duane R., and Michael G. Rinaldi. Diagnosis and Treatment of Human Mycoses. Totowa, N.J.: Humana Press, 2007, p. 296-297. C. immitis is more common west ...
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Coccidioides Posadasii
''Coccidioides posadasii'' is a pathogenic fungus that, along with ''Coccidioides immitis'', is the causative agent of coccidioidomycosis, or valley fever in humans. It resides in the soil in certain parts of the Southwestern United States, northern Mexico, and some other areas in the Americas, but its evolution was connected to its animal hosts. ''C. posadasii'' and ''C. immitis'' are morphologically identical, but genetically and epidemiologically distinct. ''C. posadasii'' was identified as a separate species other than ''C. immitis'' in 2002 after a phylogenetic analysis. The two species can be distinguished by DNA polymorphisms and different rates of growth in the presence of high salt concentrations: ''C. posadasii'' grows more slowly. It also differs epidemiologically, since it is found outside the San Joaquin Valley. Unlike ''C. immitis'', which is geographically largely limited to California, ''C. posadasii'' can also be found in northern Mexico and South America. Earl ...
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