Austrocortirubin
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Austrocortirubin
Austrocortirubin is an antibacterial metabolite found in the '' Dermocybe splendida'' mushroom. Notes Antimicrobials Natural phenols Tetrahydroxyanthraquinones Ethers 3-Hydroxypropenals within hydroxyquinones {{organic-compound-stub ...
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Dermocybe Splendida
The fungi of the ''Dermocybe'' group, commonly known as skin-heads, form a group within the huge genus ''Cortinarius''. They are generally considered to be a subgenus though some authorities consider them to form a genus in their own right. They can be distinguished from other ''Cortinarius'' species by: #their brilliant colours, especially of the gills, #their non-hygrophanous dry cap, and #their dry cylindrical (non-bulbous) stem. An example with a vivid green colour is '' Dermocybe austroveneta''. Another example is ''D. semisanguinea'' (pictured), which from above is an ordinary brown colour, but which shows a striking blood-red sheen when the underside of the cap is viewed. Lethal webcaps one of world's most poisonous mushrooms belongs to the group. The Austrian Professor Meinhard Moser Meinhard Michael Moser (13 March 192430 September 2002) was an Austrian mycologist. His work principally concerned the taxonomy, chemistry, and toxicity of the gilled mushrooms (Aga ...
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Antimicrobials
An antimicrobial is an agent that kills microorganisms or stops their growth. Antimicrobial medicines can be grouped according to the microorganisms they act primarily against. For example, antibiotics are used against bacteria, and antifungals are used against fungi. They can also be classified according to their function. Agents that kill microbes are microbicides, while those that merely inhibit their growth are called bacteriostatic agents. The use of antimicrobial medicines to treat infection is known as antimicrobial chemotherapy, while the use of antimicrobial medicines to prevent infection is known as antimicrobial prophylaxis. The main classes of antimicrobial agents are disinfectants (non-selective agents, such as bleach), which kill a wide range of microbes on non-living surfaces to prevent the spread of illness, antiseptics (which are applied to living tissue and help reduce infection during surgery), and antibiotics (which destroy microorganisms within the body). ...
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Natural Phenols
In organic chemistry, phenols, sometimes called phenolics, are a class of chemical compounds consisting of one or more hydroxyl groups (— O H) bonded directly to an aromatic hydrocarbon group. The simplest is phenol, . Phenolic compounds are classified as simple phenols or polyphenols based on the number of phenol units in the molecule. Phenols are both synthesized industrially and produced by plants and microorganisms. Properties Acidity Phenols are more acidic than typical alcohols. The acidity of the hydroxyl group in phenols is commonly intermediate between that of aliphatic alcohols and carboxylic acids (their pKa is usually between 10 and 12). Deprotonation of a phenol forms a corresponding negative phenolate ion or phenoxide ion, and the corresponding salts are called phenolates or phenoxides (aryloxides according to the IUPAC Gold Book). Condensation with aldehydes and ketones Phenols are susceptible to Electrophilic aromatic substitutions. Condensation with formald ...
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Ethers
In organic chemistry, ethers are a class of compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. They have the general formula , where R and R′ represent the alkyl or aryl groups. Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. A typical example of the first group is the solvent and anaesthetic diethyl ether, commonly referred to simply as "ether" (). Ethers are common in organic chemistry and even more prevalent in biochemistry, as they are common linkages in carbohydrates and lignin. Structure and bonding Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141  pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is ...
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