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Artificial Urinary Bladder
The two main methods for replacing bladder function involve either redirecting urine flow or replacing the bladder ''in situ''. Replacement can be done with an artificial urinary bladder, an artificial organ. Development On January 30, 1999, scientists announced that a lab-grown bladder had been successfully transplanted into dogs. These artificial bladders worked well for almost a year in the dogs. In 2000, a new procedure for creating artificial bladders for humans was developed. This procedure is called an orthotopic neobladder procedure. This procedure involves shaping a part (usually 35 to 40 inches) of a patient's small intestine to form a new bladder; however, these bladders made of intestinal tissues produced unpleasant side-effects. In 2006, the first publication of experimental transplantation of bioengineered bladders appeared in ''The Lancet''. * The trial involved seven people with spina bifida between the ages of four and nineteen who had been followed for up to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cleveland Clinic
Cleveland Clinic is a nonprofit American academic medical center based in Cleveland, Ohio. Owned and operated by the Cleveland Clinic Foundation, an Ohio nonprofit corporation established in 1921, it runs a 170-acre (69 ha) campus in Cleveland, as well as 11 affiliated hospitals, 19 family health centers in Northeast Ohio, and hospitals in Florida and Nevada. International operations include the Cleveland Clinic Abu Dhabi hospital in the United Arab Emirates and Cleveland Clinic Canada, which has two executive health and sports medicine clinics in Toronto."Facts & Figures" Cleveland Clinic. Another hospital campus in the United Kingdom, Cleveland Clinic London, opened to outpatients in 2021 and is scheduled to fully open in 2022. Tomislav Mihaljevic is the president and CEO. Cleveland Cl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Artificial Organ
An artificial organ is a human made organ device or tissue that is implanted or integrated into a human — interfacing with living tissue — to replace a natural organ, to duplicate or augment a specific function or functions so the patient may return to a normal life as soon as possible. The replaced function does not have to be related to life support, but it often is. For example, replacement bones and joints, such as those found in hip replacements, could also be considered artificial organs. Implied by definition, is that the device must not be continuously tethered to a stationary power supply or other stationary resources such as filters or chemical processing units. (Periodic rapid recharging of batteries, refilling of chemicals, and/or cleaning/replacing of filters would exclude a device from being called an artificial organ.) Thus, a dialysis machine, while a very successful and critically important life support device that almost completely replaces the duties of a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Small Intestine
The small intestine or small bowel is an organ (anatomy), organ in the human gastrointestinal tract, gastrointestinal tract where most of the #Absorption, absorption of nutrients from food takes place. It lies between the stomach and large intestine, and receives bile and pancreatic juice through the pancreatic duct to aid in digestion. The small intestine is about long and folds many times to fit in the abdomen. Although it is longer than the large intestine, it is called the small intestine because it is narrower in diameter. The small intestine has three distinct regions – the duodenum, jejunum, and ileum. The duodenum, the shortest, is where preparation for absorption through small finger-like protrusions called intestinal villus, villi begins. The jejunum is specialized for the absorption through its lining by enterocytes: small nutrient particles which have been previously digested by enzymes in the duodenum. The main function of the ileum is to absorb vitamin B12, vita ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spina Bifida
Spina bifida (Latin for 'split spine'; SB) is a birth defect in which there is incomplete closing of the spine and the membranes around the spinal cord during early development in pregnancy. There are three main types: spina bifida occulta, meningocele and myelomeningocele. Meningocele and myelomeningocele may be grouped as spina bifida cystica. The most common location is the lower back, but in rare cases it may be in the middle back or neck. Occulta has no or only mild signs, which may include a hairy patch, dimple, dark spot or swelling on the back at the site of the gap in the spine. Meningocele typically causes mild problems, with a sac of fluid present at the gap in the spine. Myelomeningocele, also known as open spina bifida, is the most severe form. Problems associated with this form include poor ability to walk, impaired bladder or bowel control, accumulation of fluid in the brain (hydrocephalus), a tethered spinal cord and latex allergy. Learning problems are relat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wake Forest University School Of Medicine
Wake Forest University School of Medicine is the medical school of Wake Forest University, with two campuses located in Winston-Salem, North Carolina and Charlotte, North Carolina, United States. It is affiliated with Atrium Health Wake Forest Baptist, the academic medical center whose clinical arm is Atrium Health Wake Forest Baptist. In 2021, ''U.S. News & World Report'' ranked Wake Forest School of Medicine 48th best for research in the nation and 80th best for primary care. The School of Medicine also ranks in the top third of U.S. medical schools in funding from the National Institutes of Health (NIH). Winston-Salem Campus History and background In 1902, the two-year Wake Forest College Medical School was founded on the college campus in Wake Forest, North Carolina. Thirteen students made up the charter medical class. Tuition was $37.50 per term; additional fees were charged for laboratories and student health care. The Southern Baptist denomination in 1919 began its fir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boston Children's Hospital
Boston Children's Hospital formerly known as Children's Hospital Boston until 2012 is a nationally ranked, freestanding acute care children's hospital located in Boston, Massachusetts, adjacent both to its teaching affiliate, Harvard Medical School, and to Dana–Farber Cancer Institute. Dana–Farber and Children's jointly operate the Dana–Farber/Boston Children's Cancer and Blood Disorders Center to deliver comprehensive care for all types of childhood cancers. The hospital is home to the largest hospital-based pediatric research program in the world. The hospital features 485 pediatric beds and provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout Massachusetts, the United States, and the world. The hospital also sometimes treats adults that require pediatric care. The hospital uses the Brigham and Women's Hospital's rooftop helipad and is an ACS verified level I pediatric trauma center, one of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthony Atala
Anthony Atala, M.D., (born July 14, 1958) is an American bioengineer, urologist, and pediatric surgeon. He is the W.H. Boyce professor of urology, the founding director of the Wake Forest Institute for Regenerative Medicine, and the chair of the Department of Urology at Wake Forest School of Medicine in North Carolina. His work focuses on the science of regenerative medicine: "a practice that aims to refurbish diseased or damaged tissue using the body's own healthy cells". Dr. Atala is the creator of the first 3D bioprinters (Integrated Tissue and Organ Printing System or ITOP) and is one of the foremost leading figures in the field of organ printing. Atala and his team developed the first lab-grown organ (a bladder) to be implanted into a human. He is also developing experimental technology that can 3D print human tissue on demand. As director of the Wake Forest Institute for Regenerative Medicine, Dr. Atala leads a team of more than 400 researchers dedicated to developing ce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Autologous
Autotransplantation is the transplantation of organs, tissues, or even particular proteins from one part of the body to another in the same person ('' auto-'' meaning "self" in Greek). The autologous tissue (also called autogenous, autogeneic, or autogenic tissue) transplanted by such a procedure is called an autograft or autotransplant. It is contrasted with allotransplantation (from other individual of the same species), syngeneic transplantation (grafts transplanted between two genetically identical individuals of the same species) and xenotransplantation (from other species). A common example is the removal of a piece of bone (usually from the hip) and its being ground into a paste for the reconstruction of another portion of bone. Autotransplantation, although most common with blood, bone, or skin, can be used for a wide variety of organs. One of the rare examples is autotransplantation of a kidney from one side of the body to the other. Kidney autotransplantation is u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transplant Rejection
Transplant rejection occurs when transplanted tissue is rejected by the recipient's immune system, which destroys the transplanted tissue. Transplant rejection can be lessened by determining the molecular similitude between donor and recipient and by use of immunosuppressant drugs after transplant. Types of transplant rejection Transplant rejection can be classified into three types: hyperacute, acute, and chronic. These types are differentiated by how quickly the recipient's immune system is activated and the specific aspect or aspects of immunity involved. Hyperacute rejection Hyperacute rejection is a form of rejection that manifests itself in the minutes to hours following transplantation. It is caused by the presence of pre-existing antibodies in the recipient that recognize antigens in the donor organ. These antigens are located on the endothelial lining of blood vessels within the transplanted organ and, once antibodies bind, will lead to the rapid activation of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Urinary Bladder
The urinary bladder, or simply bladder, is a hollow organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination. In humans the bladder is a distensible organ that sits on the pelvic floor. Urine enters the bladder via the ureters and exits via the urethra. The typical adult human bladder will hold between 300 and (10.14 and ) before the urge to empty occurs, but can hold considerably more. The Latin phrase for "urinary bladder" is ''vesica urinaria'', and the term ''vesical'' or prefix ''vesico -'' appear in connection with associated structures such as vesical veins. The modern Latin word for "bladder" – ''cystis'' – appears in associated terms such as cystitis (inflammation of the bladder). Structure In humans, the bladder is a hollow muscular organ situated at the base of the pelvis. In gross anatomy, the bladder can be divided into a broad , a body, an apex, and a neck. The apex (also called the vertex) is directed fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Voice Of America
Voice of America (VOA or VoA) is the state-owned news network and international radio broadcaster of the United States of America. It is the largest and oldest U.S.-funded international broadcaster. VOA produces digital, TV, and radio content in 48 languages which it distributes to affiliate stations around the globe. It is primarily viewed by a non-American audience. VOA was established in 1942, and the VOA charter (Public Laws 94-350 and 103–415) was signed into law in 1976 by President Gerald Ford. VOA is headquartered in Washington, D.C., and overseen by the U.S. Agency for Global Media (USAGM), an independent agency of the U.S. government. Funds are appropriated annually under the budget for embassies and consulates. In 2016, VOA broadcast an estimated 1,800 hours of radio and TV programming each week to approximately 236.6 million people worldwide with about 1,050 employees and a taxpayer-funded annual budget of . While Voice of America is seen by some foreign liste ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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