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Anisocoria
Anisocoria is a condition characterized by an unequal size of the eyes' pupils. Affecting up to 20% of the population, anisocoria is often entirely harmless, but can be a sign of more serious medical problems. Causes Anisocoria is a common condition, defined by a diameter difference of 0.4 mm or more between the sizes of the pupils of the eyes. Anisocoria has various causes: * Physiological anisocoria: About 20% of the population has a slight difference in pupil size, which is known as physiological anisocoria. In this condition, the difference between pupils is usually less than 1 mm. * Horner's syndrome * Mechanical anisocoria: Occasionally, previous trauma, eye surgery, or inflammation ( uveitis, angle closure glaucoma) can lead to adhesions between the iris and the lens. * Adie tonic pupil: Tonic pupil is usually an isolated benign entity, presenting in young women. It may be associated with loss of deep tendon reflex (Adie's syndrome). Tonic pupil is charac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mechanical Anisocoria
Mechanical anisocoria refers to anisocoria, a common eye condition in which the two pupils differ in size, that is the result of damage to the iris dilator muscle, which may be caused by trauma, angle-closure glaucoma, surgery such as cataract removal, or uveitis (inflammation of the eye). Slit lamp In ophthalmology and optometry, a slit lamp is an instrument consisting of a high-intensity light source that can be focused to shine a thin sheet of light into the eye. It is used in conjunction with a biomicroscope. The lamp facilitates an ... examination is often used as a diagnostic aid: damage to the dilator muscle is indicated by anisocoria when light intensity is lowered. References Eye diseases {{eye-disease-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tropicamide
Tropicamide, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with the examination of the eye. Specifically it is used to help examine the back of the eye. It is applied as eye drops. Effects occur within 40 minutes and last for up to a day. Common side effects include blurry vision, increased intraocular pressure, and sensitivity to light. Another rare but severe side effect is psychosis, particularly in children. It is unclear if use during pregnancy is safe for the fetus. Tropicamide is in the antimuscarinic part of the anticholinergic family of medications. It works by making the muscles within the eye unable to respond to nerve signals. Tropicamide was approved for medical use in the United States in 1960. It is on the World Health Organization's List of Essential Medicines. Medical use Tropicamide is an antimuscarinic drug that produces short acting mydriasis (dilation of the pupil) and cycloplegia whe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Third Cranial Nerve
The oculomotor nerve, also known as the third cranial nerve, cranial nerve III, or simply CN III, is a cranial nerve that enters the orbit through the superior orbital fissure and innervates extraocular muscles that enable most movements of the eye and that raise the eyelid. The nerve also contains fibers that innervate the intrinsic eye muscles that enable pupillary constriction and accommodation (ability to focus on near objects as in reading). The oculomotor nerve is derived from the basal plate of the embryonic midbrain. Cranial nerves IV and VI also participate in control of eye movement. Structure The oculomotor nerve originates from the third nerve nucleus at the level of the superior colliculus in the midbrain. The third nerve nucleus is located ventral to the cerebral aqueduct, on the pre-aqueductal grey matter. The fibers from the two third nerve nuclei located laterally on either side of the cerebral aqueduct then pass through the red nucleus. From the red nuc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pupil
The pupil is a hole located in the center of the iris of the eye that allows light to strike the retina.Cassin, B. and Solomon, S. (1990) ''Dictionary of Eye Terminology''. Gainesville, Florida: Triad Publishing Company. It appears black because light rays entering the pupil are either absorbed by the tissues inside the eye directly, or absorbed after diffuse reflections within the eye that mostly miss exiting the narrow pupil. The size of the pupil is controlled by the iris, and varies depending on many factors, the most significant being the amount of light in the environment. The term "pupil" was coined by Gerard of Cremona. In humans, the pupil is circular, but its shape varies between species; some cats, reptiles, and foxes have vertical slit pupils, goats and sheep have horizontally oriented pupils, and some catfish have annular types. In optical terms, the anatomical pupil is the eye's aperture and the iris is the aperture stop. The image of the pupil as seen from o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cocaine
Cocaine is a tropane alkaloid and central nervous system stimulant, derived primarily from the leaves of two South American coca plants, ''Erythroxylum coca'' and ''Erythroxylum novogranatense, E. novogranatense'', which are cultivated almost exclusively in the Andes. Indigenous peoples of South America, Indigenous South Americans have traditionally used coca leaves for over a thousand years. Notably, there is no evidence that habitual coca leaf use causes addiction or withdrawal, unlike cocaine. Medically, cocaine is rarely employed, mainly as a topical medication under controlled settings, due to its high abuse potential, adverse effects, and expensive cost. Despite this, recreational drug use, recreational use is widespread, driven by its euphoric and aphrodisiac properties. Levamisole induced necrosis syndrome (LINES)-a complication of the common cocaine Lacing (drugs), cutting agent levamisole-and prenatal cocaine exposure is particularly harmful. Street cocaine is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physiological Anisocoria
Physiological anisocoria is when human pupils differ in size. It is generally considered to be benign, though it must be distinguished from congenital Horner's syndrome, pharmacological dilatation, or other conditions connected to the sympathetic nervous system The sympathetic nervous system (SNS or SANS, sympathetic autonomic nervous system, to differentiate it from the somatic nervous system) is one of the three divisions of the autonomic nervous system, the others being the parasympathetic nervous sy .... The prevalence of physiological anisocoria has not been found to be influenced by the sex, age, or iris color of the subject. Presentation The main characteristic that distinguishes physiological anisocoria is an increase of pupil size with lower light or reduced illumination, such that the pupils differ in size between the two eyes. At any given eye examination, up to 41% of healthy patients can show an anisocoria of 0.4 mm or more at one time or another. It can also o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Horner's Syndrome
Horner's syndrome, also known as oculosympathetic paresis, is a combination of symptoms that arises when a group of nerves known as the sympathetic trunk is damaged. The signs and symptoms occur on the same side (ipsilateral) as it is a lesion of the sympathetic trunk. It is characterized by miosis (a constricted pupil), partial ptosis (a weak, droopy eyelid), apparent anhidrosis (decreased sweating), with apparent enophthalmos (inset eyeball). The nerves of the sympathetic trunk arise from the spinal cord in the chest, and from there ascend to the neck and face. The nerves are part of the sympathetic nervous system, a division of the autonomic (or involuntary) nervous system. Once the syndrome has been recognized, medical imaging and response to particular eye drops may be required to identify the location of the problem and the underlying cause. Signs and symptoms Signs that are found in people with Horner's syndrome on the affected side of the face include the following ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uveitis
Uveitis () is inflammation of the uvea, the pigmented layer of the eye between the inner retina and the outer fibrous layer composed of the sclera and cornea. The uvea consists of the middle layer of pigmented vascular structures of the eye and includes the iris, ciliary body, and choroid. Uveitis is described anatomically, by the part of the eye affected, as anterior, intermediate or posterior, or panuveitic if all parts are involved. Anterior uveitis ( iridocyclitis) is the most common, with the incidence of uveitis overall affecting approximately 1:4500, most commonly those between the ages of 20–60. Symptoms include eye pain, eye redness, floaters and blurred vision, and ophthalmic examination may show dilated ciliary blood vessels and the presence of cells in the anterior chamber. Uveitis may arise spontaneously, have a genetic component, or be associated with an autoimmune disease or infection. While the eye is a relatively protected environment, its immune mecha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloids
Alkaloids are a broad class of naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large variety of organisms including bacteria, fungi, plants, and animals. They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography. Alkaloids have a wide range of pharmacological activities including antimalarial (e.g. quinine), antiasthma (e.g. ephedrine), anticancer (e.g. homoharringtonine), cholinomimetic (e.g. galantamine), vasodilatory (e.g. vincamine), antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and antihyperglycemic activities (e.g. berberine). Many have found use in traditional or modern medicine, or as starting points for drug discovery. Other alkaloids possess psychotropic (e.g. psilocin) and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Judd Hirsch
Judd Seymore Hirsch (born March 15, 1935) is an American actor. He is known for playing Alex Rieger on the television comedy series ''Taxi'' (1978–1983), John Lacey on the NBC series '' Dear John'' (1988–1992), and Alan Eppes on the CBS series ''Numb3rs'' (2005–2010). He is also well known for his career in theatre and for his roles in films such as ''Ordinary People'' (1980), '' Running on Empty'' (1988), ''Independence Day'' (1996), '' A Beautiful Mind'' (2001), '' Independence Day: Resurgence'' (2016), '' Uncut Gems'' (2019), and '' The Fabelmans'' (2022). Hirsch has twice won the Primetime Emmy Award for Outstanding Lead Actor in a Comedy Series, has twice won the Tony Award for Best Actor in a Play, has won the Golden Globe Award for Best Actor in a Television Series – Musical or Comedy, and was nominated twice for the Academy Award for Best Supporting Actor for his performances in ''Ordinary People'' (1980) and ''The Fabelmans'' (2022). Early life and education ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Conversation (website)
''The Conversation'' is a network of nonprofit media outlets publishing news stories and research reports online, authored by academics with professional journalist editors to produce accessible research-informed outputs. Articles are written by academics and researchers under a Creative Commons license, allowing reuse without modification. Copyright terms for images are generally listed in the image caption and attribution. Its model has been described as explanatory journalism. Except in "exceptional circumstances", it only publishes articles by "academics employed by, or otherwise formally connected to, accredited institutions, including universities and accredited research bodies". The website was launched in Australia in March 2011. The network has since expanded globally with a variety of local editions originating from around the world. In September 2019, ''The Conversation'' reported a monthly online audience of 10.7 million users, and a combined reach o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
David Bowie
David Robert Jones (8 January 194710 January 2016), known as David Bowie ( ), was an English singer, songwriter and actor. Regarded as one of the most influential musicians of the 20th century, Bowie was acclaimed by critics and musicians, particularly for his innovative work during the 1970s. His career was marked by reinvention and visual presentation, and his music and stagecraft have had a great impact on popular music. Bowie studied art, music and design before embarking on a professional career as a musician in 1963. He released a string of unsuccessful singles with local bands and David Bowie (1967 album), a self-titled solo album (1967) before achieving his first top-five entry on the UK singles chart with "Space Oddity" (1969). After a period of experimentation, he re-emerged in 1972 during the glam rock era with the alter ego Ziggy Stardust (character), Ziggy Stardust. The success of the single "Starman (song), Starman" and its album ''The Rise and Fall of Ziggy Star ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
