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William Withering
William Withering FRS (17 March 1741 – 6 October 1799) was an English botanist, geologist, chemist, physician and first systematic investigator of the bioactivity of digitalis. Withering was born in Wellington, Shropshire, the son of a surgeon. He trained as a physician and studied medicine at the University of Edinburgh Medical School. He worked at Birmingham General Hospital from 1779. The story is that he noticed a person with dropsy (swelling from congestive heart failure) improve remarkably after taking a traditional herbal remedy; Withering became famous for recognising that the active ingredient in the mixture came from the foxglove plant. The active ingredient is now known as digoxin, after the plant's scientific name. In 1785, Withering published ''An Account of the Foxglove and some of its Medical Uses'', which contained reports on clinical trials and notes on digitalis's effects and toxicity. Biography Born in England, Withering attended Edinburgh Medical School ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wellington, Shropshire
Wellington is a market town in Telford and Wrekin, Shropshire, England. It is situated 4 miles (6 km) northwest of central Telford and 12 miles (19 km) east of Shrewsbury. The summit of The Wrekin lies 3 miles southwest of the town. The total town population of Wellington was 25,554 in 2011, making it by far the largest of the borough towns and the third largest town in Shropshire if counting it as its own town separate from Telford itself. History A church has stood for almost 1,000 years and a priest is mentioned in the Domesday Book. The original churchyard still remains. A new church, designed by George Steuart, was built in 1789. Wellington's first market charter was granted to Giles of Erdington, lord of the manor, in 1244 and a market still exists today. The market had an open-sided market hall by 1680, and possibly much earlier, but it was dismantled in about 1805. In 1841 a market company was formed to purchase the market rights from Lord Forester in 1856. In ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Herbal Remedy
Herbal medicine (also herbalism) is the study of pharmacognosy and the use of medicinal plants, which are a basis of traditional medicine. With worldwide research into pharmacology, some herbal medicines have been translated into modern remedies, such as the anti-malarial group of drugs called artemisinin isolated from ''Artemisia annua'', a herb that was known in Chinese medicine to treat fever. There is limited scientific evidence for the safety and efficacy of plants used in 21st century herbalism, which generally does not provide standards for purity or dosage. The scope of herbal medicine commonly includes fungal and bee products, as well as minerals, shells and certain animal parts. Herbal medicine is also called phytomedicine or phytotherapy. Paraherbalism describes alternative and pseudoscientific practices of using unrefined plant or animal extracts as unproven medicines or health-promoting agents. Paraherbalism relies on the belief that preserving various substances f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Joseph Priestley
Joseph Priestley (; 24 March 1733 – 6 February 1804) was an English chemist, natural philosopher, separatist theologian, grammarian, multi-subject educator, and liberal political theorist. He published over 150 works, and conducted experiments in electricity and other areas of science. He was a close friend of, and worked in close association with Benjamin Franklin involving electricity experiments. Priestley is credited with his independent discovery of oxygen by the thermal decomposition of mercuric oxide, having isolated it in 1774. During his lifetime, Priestley's considerable scientific reputation rested on his invention of carbonated water, his writings on electricity, and his discovery of several "airs" (gases), the most famous being what Priestley dubbed "dephlogisticated air" (oxygen). Priestley's determination to defend phlogiston theory and to reject what would become the chemical revolution eventually left him isolated within the scientific community. Prie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Priestley Riots
The Priestley Riots (also known as the Birmingham Riots of 1791) took place from 14 July to 17 July 1791 in Birmingham, England; the rioters' main targets were religious dissenters, most notably the politically and theologically controversial Joseph Priestley. Both local and national issues stirred the passions of the rioters, from disagreements over public library book purchases, to controversies over Dissenters' attempts to gain full civil rights and their support of the French Revolution. The riots started with an attack on the Royal Hotel, Birmingham—the site of a banquet organised in sympathy with the French Revolution. Then, beginning with Priestley's church and home, the rioters attacked or burned four Dissenting chapels, twenty-seven houses, and several businesses. Many of them became intoxicated by liquor that they found while looting, or with which they were bribed to stop burning homes. A small core could not be bribed, however, and remained sober. The rioters bur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edgbaston Hall
Edgbaston Hall () is a country house (albeit now in the middle of the city) in the Edgbaston area of Birmingham, England. Description and current usage Since 1936, thanks to negotiations initiated by The Birmingham Civic Society with the owner, Calthorpe Estates, it has been the clubhouse for Edgbaston Golf Club. Edgbaston Hall, and its lodge house, are Grade II listed buildings. The grounds, featuring Edgbaston Pool, are now divided into an 18-hole golf course and a nature reserve. History Early in the Civil War, Edgbaston Hall, along with Hawkesley House, now the site of a council housing estate in Longbridge, was a stronghold of Colonel John Fox, the so-called "Jovial Tinker". The Edgbaston Garrison musters from August 19, 1645 to April 30, 1646, can be found among the accounts of the Warwickshire County Committee, which was the Parliamentary Committee of accounts for the County, along with musters, warrants, levy assessments and other documents submitted by field officers a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pulmonary Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is ba ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lunar Society
The Lunar Society of Birmingham was a British dinner club and informal learned society of prominent figures in the Midlands Enlightenment, including industrialists, natural philosophers and intellectuals, who met regularly between 1765 and 1813 in Birmingham. At first called the Lunar Circle, "Lunar Society" became the formal name by 1775. The name arose because the society would meet during the full moon, as the extra light made the journey home easier and safer in the absence of street lighting. The members cheerfully referred to themselves as ''"lunaticks"'', a pun on lunatics. Venues included Erasmus Darwin's home in Lichfield, Matthew Boulton's home, Soho House, Bowbridge House in Derbyshire, and Great Barr Hall. Membership and status The Lunar Society evolved through various degrees of organisation over a period of up to fifty years, but was only ever an informal group. No constitution, minutes, publications or membership lists survive from any period, and evidence of its ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erasmus Darwin
Erasmus Robert Darwin (12 December 173118 April 1802) was an English physician. One of the key thinkers of the Midlands Enlightenment, he was also a natural philosopher, physiologist, slave-trade abolitionist, inventor, and poet. His poems included much natural history, including a statement of evolution and the relatedness of all forms of life. He was a member of the Darwin–Wedgwood family, which includes his grandsons Charles Darwin and Francis Galton. Darwin was a founding member of the Lunar Society of Birmingham, a discussion group of pioneering industrialists and natural philosophers. He turned down an invitation from George III to become Physician to the King. Early life and education Darwin was born in 1731 at Elston Hall, Nottinghamshire, near Newark-on-Trent, England, the youngest of seven children of Robert Darwin of Elston (1682–1754), a lawyer and physician, and his wife Elizabeth Hill (1702–97). The name Erasmus had been used by a number of his f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edinburgh Medical School
The University of Edinburgh Medical School (also known as Edinburgh Medical School) is the medical school of the University of Edinburgh in Scotland and the United Kingdom and part of the College of Medicine and Veterinary Medicine. It was established in 1726, during the Scottish Enlightenment, making it the oldest medical school in the United Kingdom and is one of the oldest medical schools in the English-speaking world. It is widely regarded as one of the best medical schools in the United Kingdom and the world. The medical school in 2022 was ranked 1st in the UK by the Guardian University Guide, In 2021, it was ranked third in the UK by The Times University Guide, and the Complete University Guide. It also ranked 21st in the world by both the Times Higher Education World University Rankings and the QS World University Rankings in the same year. According to a Healthcare Survey run by Saga in 2006, the medical school's main teaching hospital, the Royal Infirmary of Edinburgh, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edgbaston Hall 02
Edgbaston () is an affluent suburban area of central Birmingham, England, historically in Warwickshire, and curved around the southwest of the city centre. In the 19th century, the area was under the control of the Gough-Calthorpe family and the Gillott family who refused to allow factories or warehouses to be built in Edgbaston, thus making it attractive for the wealthier residents of the city. It then came to be known as "where the trees begin". One of these private houses is grade one listed and open to the public. The majority of Edgbaston that falls under the B15 postcode finds itself being part of the Calthorpe Estate. The estate is an active conservation area, and it is here that the areas most prized properties are situated. The exclusivity of Edgbaston is down to its array of multi-million listed Georgian and Victorian villas, making it one of the most expensive postcodes outside of London. Edgbaston boasts facilities such as Edgbaston Cricket Ground, a Test mat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Digoxin Toxicity
Digoxin toxicity, also known as digoxin poisoning, is a type of poisoning that occurs in people who take too much of the medication digoxin or eat plants such as foxglove that contain a similar substance. Symptoms are typically vague. They may include vomiting, loss of appetite, confusion, blurred vision, changes in color perception, and decreased energy. Potential complications include an irregular heartbeat, which can be either too fast or too slow. Toxicity may occur over a short period of time following an overdose or gradually during long-term treatment. Risk factors include low potassium, low magnesium, and high calcium. Digoxin is a medication used for heart failure or atrial fibrillation. An electrocardiogram is a routine part of diagnosis. Blood levels are only useful more than six hours following the last dose. Activated charcoal may be used if it can be given within two hours of the person taking the medication. Atropine may be used if the heart rate is slow whi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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