William Hewson (surgeon)
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William Hewson (surgeon)
William Hewson (14 November 1739 – 1 May 1774) was a British surgery, surgeon, anatomy, anatomist and physiology, physiologist who has been referred to as the "father of haematology". Biography Born in Hexham, Northumberland, Hewson initially studied in 1753 at the Newcastle Infirmary, Newcastle upon Tyne (which later became the Royal Victoria Infirmary) under its founder Richard Lambert (surgeon), Richard Lambert and much later in the winter of 1761/1762 in Edinburgh and was a student, and later an assistant, of William Hunter (anatomist), William Hunter. In 1768 he was elected to the American Philosophical Society, he was awarded the Copley Medal in 1769, and elected to the Royal Society in 1770. His major contribution was in isolating fibrin, a key protein in the blood coagulation process. His Copley work came when he showed the existence of lymph vessels in animals and explained their function by hypothesizing the existence of a human lymphatic system. He also demonstrated ...
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Hexham
Hexham ( ) is a market town and civil parish in Northumberland, England, on the south bank of the River Tyne, formed by the confluence of the North Tyne and the South Tyne at Warden nearby, and close to Hadrian's Wall. Hexham was the administrative centre for the Tynedale district from 1974 to 2009. In 2011, it had a population of 13,097. Smaller towns and villages around Hexham include Corbridge, Riding Mill, Stocksfield and Wylam to the east, Acomb and Bellingham to the north, Allendale to the south and Haydon Bridge, Bardon Mill and Haltwhistle to the west. Newcastle upon Tyne is to the east and Carlisle to the west. Toponym The name Hexham derives from the Old English ''Hagustaldes ea'' and later ''Hagustaldes ham'' from which the modern form (with the "-ham" element) derives. ''Hagustald'' is related to the Old High German ''hagustalt'', denoting a younger son who takes land outside the settlement; the element ''ea'' means "stream" or "river" and ''ham'' is the O ...
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American Philosophical Society
The American Philosophical Society (APS) is an American scholarly organization and learned society founded in 1743 in Philadelphia that promotes knowledge in the humanities and natural sciences through research, professional meetings, publications, source text, library resources, and community outreach. It was founded by the polymath Benjamin Franklin and is considered the first learned society founded in what became the United States.Philosophical Hall, the society's headquarters and a museum, is located just east of Independence Hall in Independence National Historical Park. In 1965, in recognition of the building's history, it was designated a National Historic Landmark. The society has about 1,000 elected members. As of April 2020, 5,710 members had been inducted since its creation. Through research grants, published journals, the American Philosophical Society Museum, an extensive library, and regular meetings, the society supports a variety of disciplines in the humanitie ...
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Paul Knapman
Paul Knapman DL was Her Majesty's coroner for Westminster (and Inner West London), from 1980 to 2011 (and deputy coroner from 1975 to 1980). His responsibility for investigating sudden deaths as an independent judicial officer saw him preside over numerous notable cases. He was made a deputy lieutenant of Greater London in 2008 and advanced to the representative deputy lieutenant for Westminster in 2013. Early life Paul Knapman went to Epsom College, Surrey, King's College London, and St George's Hospital Medical School, London, where he qualified as a doctor – MB, BS (1968). He then proceeded to read for the Bar at the Council of Legal Education, and was called to the Bar as a barrister by Gray's Inn in 1972. Honours * Two medicolegal diplomas, namely DMJ in 1975 and FFLM in 2005 * FRCP (Honoris Causa) in 1997 * FRCS (Honoris Causa) in 1995 Cases and events * Inquest re: Sandra Rivett, Nanny to Lord Lucan in 1975 (deputy coroner) * Inquest re: Georgi Markov in 1978 (de ...
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The Times
''The Times'' is a British Newspaper#Daily, daily Newspaper#National, national newspaper based in London. It began in 1785 under the title ''The Daily Universal Register'', adopting its modern name on 1 January 1788. ''The Times'' and its sister paper ''The Sunday Times'' (founded in 1821), are published by Times Media, since 1981 a subsidiary of News UK, in turn wholly owned by News Corp. ''The Times'' and ''The Sunday Times'' were founded independently and have had common ownership only since 1966. It is considered a newspaper of record in the UK. ''The Times'' was the first newspaper to bear that name, inspiring numerous other papers around the world. In countries where these other titles are popular, the newspaper is often referred to as or , although the newspaper is of national scope and distribution. ''The Times'' had an average daily circulation of 365,880 in March 2020; in the same period, ''The Sunday Times'' had an average weekly circulation of 647,622. The two ...
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Benjamin Franklin House
Benjamin Franklin House is a museum in a terraced Georgian house at 36 Craven Street, London, close to Trafalgar Square in the West End of London. It is the last-standing former residence of Benjamin Franklin, one of the Founding Fathers of the United States. The house dates from c. 1730, and Franklin lived and worked there from 1757 to 1774.Tom Huntington
"Franklin's Last Home," ''American Heritage'', April/May 2006.
The museum opened to the public on 17 January 2006. The chairman is American-British investment banker and philanthropist John Studzinski. The house is
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Craven Street
Craven Street is a street in the City of Westminster, London, England, near The Strand. Several notable historical figures have lived in the street which was the home of Benjamin Franklin, when he lived in London before the American Revolution. History The street was originally known as Spur Alley. It was rebuilt around 1730 when the land was owned by the Craven family and it received its current name then. Location Craven Street runs from The Strand in the north to Northumberland Avenue in the south. Corner House Street and Hungerford Lane join Craven Street in the north and halfway along Craven Street it is crossed by Craven Passage which is pedestrian only and joins Craven Street to Northumberland Street and Hungerford Lane. Hungerford Lane rejoins Craven Street at its southern end. Residents Mark Akenside, author of '' The Pleasures of the Imagination'', lived at No. 33 from 1759 to 1761. Benjamin Franklin lived at No. 36 for sixteen years before the American Revoluti ...
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Benjamin Franklin
Benjamin Franklin (April 17, 1790) was an American polymath: a writer, scientist, inventor, statesman, diplomat, printer, publisher and Political philosophy, political philosopher.#britannica, Encyclopædia Britannica, Wood, 2021 Among the most influential intellectuals of his time, Franklin was one of the Founding Fathers of the United States; a Committee of Five, drafter and signer of the United States Declaration of Independence, Declaration of Independence; and the first United States Postmaster General, postmaster general. Born in the Province of Massachusetts Bay, Franklin became a successful Early American publishers and printers, newspaper editor and printer in Philadelphia, the leading city in the colonies, publishing ''The Pennsylvania Gazette'' at age 23. He became wealthy publishing this and ''Poor Richard's Almanack'', which he wrote under the pseudonym "Richard Saunders". After 1767, he was associated with the ''Pennsylvania Chronicle'', a newspaper known for it ...
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Cell Membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extracellular space). The cell membrane consists of a lipid bilayer, made up of two layers of phospholipids with cholesterols (a lipid component) interspersed between them, maintaining appropriate membrane fluidity at various temperatures. The membrane also contains membrane proteins, including integral proteins that span the membrane and serve as membrane transporters, and peripheral proteins that loosely attach to the outer (peripheral) side of the cell membrane, acting as enzymes to facilitate interaction with the cell's environment. Glycolipids embedded in the outer lipid layer serve a similar purpose. The cell membrane controls the movement of substances in and out of a cell, being selectively permeable to ions and organic mole ...
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Anton Van Leeuwenhoek
Antonie Philips van Leeuwenhoek ( ; ; 24 October 1632 – 26 August 1723) was a Dutch microbiologist and microscopist in the Golden Age of Dutch art, science and technology. A largely self-taught man in science, he is commonly known as " the Father of Microbiology", and one of the first microscopists and microbiologists. Van Leeuwenhoek is best known for his pioneering work in microscopy and for his contributions toward the establishment of microbiology as a scientific discipline. Raised in Delft, Dutch Republic, Van Leeuwenhoek worked as a draper in his youth and founded his own shop in 1654. He became well-recognized in municipal politics and developed an interest in lensmaking. In the 1670s, he started to explore microbial life with his microscope. Using single-lensed microscopes of his own design and make, Van Leeuwenhoek was the first to observe and to experiment with microbes, which he originally referred to as , or . He was the first to relatively determine t ...
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Red Blood Cell
Red blood cells (RBCs), referred to as erythrocytes (, with -''cyte'' translated as 'cell' in modern usage) in academia and medical publishing, also known as red cells, erythroid cells, and rarely haematids, are the most common type of blood cell and the vertebrate's principal means of delivering oxygen () to the body tissue (biology), tissues—via blood flow through the circulatory system. Erythrocytes take up oxygen in the lungs, or in fish the gills, and release it into tissues while squeezing through the body's capillary, capillaries. The cytoplasm of a red blood cell is rich in hemoglobin (Hb), an iron-containing biomolecule that can bind oxygen and is responsible for the red color of the cells and the blood. Each human red blood cell contains approximately 270 million hemoglobin molecules. The cell membrane is composed of proteins and lipids, and this structure provides properties essential for physiological Cell (biology), cell function such as erythrocyte deformabil ...
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Lymphatic System
The lymphatic system, or lymphoid system, is an organ system in vertebrates that is part of the immune system and complementary to the circulatory system. It consists of a large network of lymphatic vessels, lymph nodes, lymphoid organs, lymphatic tissue and lymph. Lymph is a clear fluid carried by the lymphatic vessels back to the heart for re-circulation. The Latin word for lymph, , refers to the deity of fresh water, "Lympha". Unlike the circulatory system that is a closed system, the lymphatic system is open. The human circulatory system processes an average of 20 litres of blood per day through Starling equation, capillary filtration, which removes blood plasma, plasma from the blood. Roughly 17 litres of the filtered blood is reabsorbed directly into the blood vessels, while the remaining three litres are left in the interstitial fluid. One of the main functions of the lymphatic system is to provide an accessory return route to the blood for the surplus three litres. The ...
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Coagulation
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a thrombus, blood clot. It results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The process of coagulation involves Platelet-activating factor, activation, Cell adhesion, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin. Coagulation begins almost instantly after an injury to the endothelium that lines a blood vessel. Exposure of blood to the subendothelial space initiates two processes: changes in platelets, and the exposure of subendothelial Tissue factor, platelet tissue factor to coagulation factor VII, which ultimately leads to cross-linked fibrin formation. Platelets immediately form a plug at the site of injury; this is called ''primary hemostasis. Secondary hemostasis'' occurs simultaneously: additional coagulation factors beyond factor VII (#Coagulation factors, listed below) respond in a c ...
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