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Timeline Of Human Prenatal Development
Changes by weeks of gestation Gestational age vs. embryonic age ''Gestational age'' is the time that has passed since the onset of the last menstruation, which generally or as standard occurs 2 weeks before the actual fertilization. ''Embryonic age'', in contrast measures the actual age of the embryo or fetus from the time of fertilization. Nevertheless, menstruation has historically been the only means of estimating embryonal/fetal age, and is still the presumed measure if not else specified. However, the actual duration between last menstruation and fertilization may in fact differ from the standard 2 weeks by several days. Thus, the first week of embryonic age is already week three counting with gestational age. Furthermore, the number of the week is one more than the actual age of the embryo/fetus. For example, the embryo is 0 whole weeks old during the 1st week after fertilization. The following table summarizes the various expression systems during week number x of gestat ...
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Fertilization
Fertilisation or fertilization (see spelling differences), also known as generative fertilisation, syngamy and impregnation, is the fusion of gametes to give rise to a new individual organism or offspring and initiate its development. Processes such as insemination or pollination which happen before the fusion of gametes are also sometimes informally called fertilisation. The cycle of fertilisation and development of new individuals is called sexual reproduction. During double fertilisation in angiosperms the haploid male gamete combines with two haploid polar nuclei to form a triploid primary endosperm nucleus by the process of vegetative fertilisation. History In Antiquity, Aristotle conceived the formation of new individuals through fusion of male and female fluids, with form and function emerging gradually, in a mode called by him as epigenetic. In 1784, Spallanzani established the need of interaction between the female's ovum and male's sperm to form a zygote in fr ...
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Conjoined Twins
Conjoined twins – sometimes popularly referred to as Siamese twins – are twins joined ''Uterus, in utero''. A very rare phenomenon, the occurrence is estimated to range from 1 in 49,000 births to 1 in 189,000 births, with a somewhat higher incidence in Southwest Asia and Africa. Approximately half are stillbirth, stillborn, and an additional one-third die within 24 hours. Most live births are female, with a ratio of 3:1. Two theories exist to explain the origins of conjoined twins. The more generally accepted theory is ''fission'', in which the fertilized egg splits partially. The other theory, no longer believed to be the basis of conjoined twinning, is ''fusion'', in which a fertilized egg completely separates, but stem cells (which search for similar cells) find similar stem cells on the other twin and fuse the twins together. Conjoined twins share a single common chorion, placenta, and amniotic sac, although these characteristics are not exclusive to conjoined twins, as th ...
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Pharyngeal Arches
The pharyngeal arches, also known as visceral arches'','' are structures seen in the embryonic development of vertebrates that are recognisable precursors for many structures. In fish, the arches are known as the branchial arches, or gill arches. In the human embryo, the arches are first seen during the fourth week of development. They appear as a series of outpouchings of mesoderm on both sides of the developing pharynx. The vasculature of the pharyngeal arches is known as the aortic arches. In fish, the branchial arches support the gills. Structure In vertebrates, the pharyngeal arches are derived from all three germ layers (the primary layers of cells that form during embryogenesis). Neural crest cells enter these arches where they contribute to features of the skull and facial skeleton such as bone and cartilage. However, the existence of pharyngeal structures before neural crest cells evolved is indicated by the existence of neural crest-independent mechanisms of pharyn ...
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Septum Primum
During heart development of a human embryo, the single primitive atrium becomes divided into right and left by a , the septum primum. The septum primum () grows downward into the single atrium. Development The gap below it is known as the ostium primum (), and becomes increasingly small. The septum primum eventually fuses with the endocardial cushion, closing the ostium primum off completely. Meanwhile, perforations appear in the superior part of the septum primum, forming the ostium secundum (). The septum primum will eventually form part of the fossa ovalis. Blood flow between atria will continue through the foramen ovale (heart). Clinical significance Failure of the septum primum to fuse with the endocardial cushion can lead to an ostium primum atrial septal defect. This is the second most common type of atrial septal defect and is commonly seen in Down syndrome. Typically this defect will cause a shunt to occur from the left atrium to the right atrium. Children born with ...
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Tubal Pregnancy With Embryo
Tubal ( he, תֻבָל, ''Ṯuḇāl'', ), in Genesis 10 (the "Table of Nations"), was the name of a son of Japheth, son of Noah. He is known to be the father of the Caucasian Iberians (ancestors of the Georgians) according to primary sources. Later, Saint Jerome refashioned the Caucasian Iberia (Georgia) into the Iberian Peninsula (Western Europe) and Isidore of Seville consolidated this mistake. Modern scholarship Modern scholarship has identified the biblical Tubal with Tabal, an Anatolian state and region mentioned in Assyrian sources. Tabal was a post-Hittite Luwian state in Asia Minor in the 1st millennium BC. Its neighbours, the Mushki, are traditionally associated with Meshech. Some historians further connect Tabal and Tubal with the tribe on the Black Sea coast later known to the Greeks as Tibareni, although this connection is uncertain. The Tibareni and nearby tribes, the ''Chalybes'' (Khalib/Khaldi) and the Mossynoeci (''Mossynoikoi'' in Greek), were sometimes consi ...
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6 Weeks Pregnant
6 (six) is the natural number following 5 and preceding 7. It is a composite number and the smallest perfect number. In mathematics Six is the smallest positive integer which is neither a square number nor a prime number; it is the second smallest composite number, behind 4; its proper divisors are , and . Since 6 equals the sum of its proper divisors, it is a perfect number; 6 is the smallest of the perfect numbers. It is also the smallest Granville number, or \mathcal-perfect number. As a perfect number: *6 is related to the Mersenne prime 3, since . (The next perfect number is 28.) *6 is the only even perfect number that is not the sum of successive odd cubes. *6 is the root of the 6-aliquot tree, and is itself the aliquot sum of only one other number; the square number, . Six is the only number that is both the sum and the product of three consecutive positive numbers. Unrelated to 6's being a perfect number, a Golomb ruler of length 6 is a "perfect ruler". Six is a con ...
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Vertebra
The spinal column, a defining synapomorphy shared by nearly all vertebrates, Hagfish are believed to have secondarily lost their spinal column is a moderately flexible series of vertebrae (singular vertebra), each constituting a characteristic irregular bone whose complex structure is composed primarily of bone, and secondarily of hyaline cartilage. They show variation in the proportion contributed by these two tissue types; such variations correlate on one hand with the cerebral/caudal rank (i.e., location within the backbone), and on the other with phylogenetic differences among the vertebrate taxa. The basic configuration of a vertebra varies, but the bone is its ''body'', with the central part of the body constituting the ''centrum''. The upper (closer to) and lower (further from), respectively, the cranium and its central nervous system surfaces of the vertebra body support attachment to the intervertebral discs. The posterior part of a vertebra forms a vertebral ar ...
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Somite
The somites (outdated term: primitive segments) are a set of bilaterally paired blocks of paraxial mesoderm that form in the embryonic stage of somitogenesis, along the head-to-tail axis in segmented animals. In vertebrates, somites subdivide into the dermatomes, myotomes, sclerotomes and syndetomes that give rise to the vertebrae of the vertebral column, rib cage, part of the occipital bone, skeletal muscle, cartilage, tendons, and skin (of the back). The word ''somite'' is sometimes also used in place of the word '' metamere''. In this definition, the somite is a homologously-paired structure in an animal body plan, such as is visible in annelids and arthropods. Development The mesoderm forms at the same time as the other two germ layers, the ectoderm and endoderm. The mesoderm at either side of the neural tube is called paraxial mesoderm. It is distinct from the mesoderm underneath the neural tube which is called the chordamesoderm that becomes the notochord. ...
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Neuromeres
Neuromeres are morphologically or molecularly defined transient segments of the early developing brain. Rhombomeres are such segments that make up the rhombencephalon or hindbrain. More controversially, some argue that there exist early developmental segments that give rise to structures of the midbrain ( mesomeres) and forebrain ( prosomeres). Neuromeres are the segments of the neural tube that establish the embryonic brain during development. They can then be divided up so that each is carrying different and unique genetic traits, expressing different features in development. Neuromeres were first discovered in the beginning of the 20th century. Although researchers have long since recognized the different signs of differentiation during embryonic development, it was widely thought that neuromeres held no relation to the structure of the nervous system. Swedish neuroembyrologists Bergquist and Kallen clarified the role of neuromeres by conducting several studies showing ...
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Brain
A brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as vision. It is the most complex organ in a vertebrate's body. In a human, the cerebral cortex contains approximately 14–16 billion neurons, and the estimated number of neurons in the cerebellum is 55–70 billion. Each neuron is connected by synapses to several thousand other neurons. These neurons typically communicate with one another by means of long fibers called axons, which carry trains of signal pulses called action potentials to distant parts of the brain or body targeting specific recipient cells. Physiologically, brains exert centralized control over a body's other organs. They act on the rest of the body both by generating patterns of muscle activity and by driving the secretion of chemicals called hormones. This centralized control allows rapid and coordinated responses ...
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Spinal Cord
The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column (backbone). The backbone encloses the central canal of the spinal cord, which contains cerebrospinal fluid. The brain and spinal cord together make up the central nervous system (CNS). In humans, the spinal cord begins at the occipital bone, passing through the foramen magnum and then enters the spinal canal at the beginning of the cervical vertebrae. The spinal cord extends down to between the first and second lumbar vertebrae, where it ends. The enclosing bony vertebral column protects the relatively shorter spinal cord. It is around long in adult men and around long in adult women. The diameter of the spinal cord ranges from in the cervical and lumbar regions to in the thoracic area. The spinal cord functions primarily in the transmission of nerve signals from the motor cortex to the ...
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Gastrulation
Gastrulation is the stage in the early embryonic development of most animals, during which the blastula (a single-layered hollow sphere of cells), or in mammals the blastocyst is reorganized into a multilayered structure known as the gastrula. Before gastrulation, the embryo is a continuous epithelial sheet of cells; by the end of gastrulation, the embryo has begun differentiation to establish distinct cell lineages, set up the basic axes of the body (e.g. dorsal-ventral, anterior-posterior), and internalized one or more cell types including the prospective gut. In triploblastic organisms, the gastrula is trilaminar (three-layered). These three germ layers are the ectoderm (outer layer), mesoderm (middle layer), and endoderm (inner layer).Mundlos 2009p. 422/ref>McGeady, 2004: p. 34 In diploblastic organisms, such as Cnidaria and Ctenophora, the gastrula has only ectoderm and endoderm. The two layers are also sometimes referred to as the ''hypoblast'' and ''epiblast''. Sp ...
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