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Tsou Plot
The Tsou plot is a graphical method of determining the number and nature of the functional groups on an enzyme that are necessary for its catalytic activity. Theory of Tsou's method Tsou Chen-Lu analysed the relationship between the functional groups of enzymes that are necessary for their biological activity and the loss of activity that occurs when the enzyme is treated with an irreversible inhibitor. Suppose now that there are n groups on each monomeric enzyme molecule that react equally fast with the modifying agent, and n_\mathrm of these are essential for catalytic activity. After modification of an average of n_\mathrm groups on each molecule, the probability that any particular group has been modified is n_\mathrm/n and the probability that it remains unmodified is (1 - n_ \mathrm)^. For the enzyme molecule to retain activity, all of its n_\mathrm essential groups must remain unmodified, for which the probability is 1 - n_\mathrm/n. The fraction f of activity remaining aft ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tsou Chen-Lu
Zou Chenglu (; 17 May 1923 – 23 November 2006), better known as Chen-Lu Tsou, was a Chinese biochemist. He was a professor of the Shanghai Institute of Biochemistry and later a professor and Deputy Director of the Institute of Biophysics, Chinese Academy of Sciences (CAS). He made important contributions to the synthesis of insulin, and was elected an academician of the CAS and The World Academy of Sciences (TWAS). He won the TWAS Prize in Biology in 1992 for his pioneering study of enzyme inhibition kinetics, and was a six-time laureate of the State Natural Science Award (three times each for First Class and Second Class). His wife, physicist Li Lin, was also an academician of the CAS. Tsou was a strong advocate against academic fraud and pseudoscience, and led a public campaign against what he called "unhealthy practices" such as administrators' interference in scientific research. Early life and education Tsou was born on 17 May 1923 in Qingdao, Shandong province, w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tsou Plot For Pepsin Inactivation
Tsou may refer to: *the Tsou people, an indigenous people of central southern Taiwan *the Tsou language * Wade-Giles Romanization of Zou (simplified Chinese: 邹; traditional Chinese: 鄒) * Peter Tsou, principal science staff member at the Jet Propulsion Laboratory * Shih-Ching Tsou, Taiwan-born, actress, director, producer * Tsou Hai-ying, birth name of Jennifer Su Jennifer Su (born 12 August 1968 as ''Tsou Hai-ying'' 鄒海音) is an American South African radio and television personality of Chinese origin. She is best known as the financial news anchor for The Africa Business Report on Sky News. She is ... (born 1968), South African radio and television personality {{disambiguation, surname Language and nationality disambiguation pages ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jeremy R
Jeremy may refer to: * Jeremy (given name), a given name * Jérémy, a French given name * Jeremy (film), ''Jeremy'' (film), a 1973 film * Jeremy (song), "Jeremy" (song), a song by Pearl Jam * Jeremy (snail), a left-coiled garden snail that died in 2017 * ''Jeremy'', a 1919 novel by Hugh Walpole See also * * * Jeremiah (other) * Jeremie (other) * Jerome (other) * Jeromy (other) {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pepsin
Pepsin is an endopeptidase that breaks down proteins into smaller peptides. It is produced in the gastric chief cells of the stomach lining and is one of the main digestive enzymes in the digestive systems of humans and many other animals, where it helps digest the proteins in food. Pepsin is an aspartic protease, using a catalytic aspartate in its active site. It is one of three principal endopeptidases (enzymes cutting proteins in the middle) in the human digestive system, the other two being chymotrypsin and trypsin. There are also exopeptidases which remove individual amino acids at both ends of proteins ( carboxypeptidases produced by the pancreas and aminopeptidases secreted by the small intestine). During the process of digestion, these enzymes, each of which is specialized in severing links between particular types of amino acids, collaborate to break down dietary proteins into their components, i.e., peptides and amino acids, which can be readily absorbed by t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trimethyloxonium Tetrafluoroborate
Trimethyloxonium tetrafluoroborate is the organic compound with the formula . (It is sometimes called "Meerwein's salt" after Hans Meerwein.Meerwein's salt classically referred to triethyloxonium tetrafluoroborate. However, in recent years, the trimethyloxonium salt has also been called Meerwein's salt.) This salt is a strong methylating agent, being a synthetic equivalent of . It is a white solid that rapidly degrades upon exposure to atmospheric moisture, although it is robust enough to be weighed quickly without inert atmosphere protection. Triethyloxonium tetrafluoroborate is a closely related compound. Preparation and reactions The compound is prepared by the reaction of boron trifluoride with dimethyl ether and epichlorohydrin: : 4 + 2 + 3 → 3 + The salt hydrolyzes readily: : + → + + Trimethyloxonium tetrafluoroborate is generally ranked as the strongest commercially available reagent for electrophilic methylation In the chemical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hans Meerwein
Hans Meerwein (May 20, 1879 in Hamburg, Germany – October 24, 1965 in Marburg, Germany) was a German chemist. Several reactions and reagents bear his name, most notably the Meerwein–Ponndorf–Verley reduction, the Wagner–Meerwein rearrangement, the Meerwein arylation reaction, and Meerwein's salt. Life and work His father was the architect, Wilhelm Emil Meerwein. He originally trained to be a chemistry technician or 'chemotechnician' at the Fresenius University of Applied Sciences (between 1898 and 1900) before studying for a chemistry degree at the University of Bonn. After finishing his PhD with Richard Anschütz he worked at the University of Berlin, before returning to Bonn where he became professor in 1914. From 1922 till 1928 he was professor for organic chemistry at the University of Königsberg. The last change in his academic career was to the University of Marburg. The war devastated the Institute and Meerwein was planning the rebuilding which was finished ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diethyl Pyrocarbonate
Diethyl pyrocarbonate (DEPC), also called diethyl dicarbonate (IUPAC name), is used in the laboratory to inactivate RNase enzymes in water and on laboratory utensils. It does so by the covalent modification of histidine (most strongly), lysine, cysteine, and tyrosine residues. DEPC-treated (and therefore RNase-free) water is used in handling of RNA in the laboratory to reduce the risk of RNA being degraded by RNases. Water is usually treated with 0.1% v/v DEPC for at least 2 hours at 37 °C and then autoclaved (at least 15 min) to inactivate traces of DEPC. Inactivation of DEPC in this manner yields CO2 and ethanol. Higher concentrations of DEPC are capable of deactivating larger amounts of RNase, but remaining traces or byproducts may inhibit further biochemical reactions such as in vitro transcription. Furthermore, chemical modification of RNA such as carboxymethylation is possible when traces of DEPC or its byproducts are present, resulting in impaired recovery of intact R ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Daniel E
Daniel is a masculine given name and a surname of Hebrew origin. It means "God is my judge"Hanks, Hardcastle and Hodges, ''Oxford Dictionary of First Names'', Oxford University Press, 2nd edition, , p. 68. (cf. Gabriel—"God is my strength"), and derives from two early biblical figures, primary among them Daniel from the Book of Daniel. It is a common given name for males, and is also used as a surname. It is also the basis for various derived given names and surnames. Background The name evolved into over 100 different spellings in countries around the world. Nicknames ( Dan, Danny) are common in both English and Hebrew; "Dan" may also be a complete given name rather than a nickname. The name "Daniil" (Даниил) is common in Russia. Feminine versions ( Danielle, Danièle, Daniela, Daniella, Dani, Danitza) are prevalent as well. It has been particularly well-used in Ireland Ireland ( ; ga, Éire ; Ulster Scots dialect, Ulster-Scots: ) is an island in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plots (graphics)
Plot or Plotting may refer to: Art, media and entertainment * Plot (narrative), the story of a piece of fiction Music * ''The Plot'' (album), a 1976 album by jazz trumpeter Enrico Rava * The Plot (band), a band formed in 2003 Other * ''Plot'' (film), a 1973 French-Italian film * ''Plotting'' (video game), a 1989 Taito puzzle video game, also called Flipull * ''The Plot'' (video game), a platform game released in 1988 for the Amstrad CPC and Sinclair Spectrum * ''Plotting'' (non-fiction), a 1939 book on writing by Jack Woodford * ''The Plot'' (novel), a 2021 mystery by Jean Hanff Korelitz Graphics * Plot (graphics), a graphical technique for representing a data set * Plot (radar), a graphic display that shows all collated data from a ship's on-board sensors * Plot plan, a type of drawing which shows existing and proposed conditions for a given area Land * Plot (land), a piece of land used for building on ** Burial plot, a piece of land a person is buried in * Quadrat, a de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
