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Tobacco Use
Tobacco is the common name of several plants in the genus ''Nicotiana'' of the family Solanaceae, and the general term for any product prepared from the cured leaves of these plants. More than 70 species of tobacco are known, but the chief commercial crop is ''N. tabacum''. The more potent variant ''N. rustica'' is also used in some countries. Dried tobacco leaves are mainly used for smoking in cigarettes and cigars, as well as pipes and shishas. They can also be consumed as snuff, chewing tobacco, dipping tobacco, and snus. Tobacco contains the highly addictive stimulant alkaloid nicotine as well as harmala alkaloids. Tobacco use is a cause or risk factor for many deadly diseases, especially those affecting the heart, liver, and lungs, as well as many cancers. In 2008, the World Health Organization named tobacco use as the world's single greatest preventable cause of death. Etymology The English word 'tobacco' originates from the Spanish word ''tabaco''. The ...
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Nicotiana
''Nicotiana'' () is a genus of herbaceous plants and shrubs in the Family (biology), family Solanaceae, that is Native plant, indigenous to the Americas, Australia, Southwestern Africa and the South Pacific. Various ''Nicotiana'' species, commonly referred to as tobacco plants, are cultivated as ornamental garden plants. ''Nicotiana tabacum, N. tabacum'' is grown worldwide for the cultivation of tobacco leaves used for manufacturing and producing List of tobacco products, tobacco products, including cigars, cigarillos, cigarettes, chewing tobacco, dipping tobacco, Snuff (tobacco), snuff, and snus. Taxonomy Species The 79 accepted and known species include: * ''Nicotiana acuminata'' (Graham) William Jackson Hooker, Hook. – manyflower tobacco or many-flowered tobaccoKnapp et al. (2004) Nomenclatural changes and a new sectional classification in ''Nicotiana'' (Solanaceae) Taxon. 53 (1):73–82. * ''Nicotiana africana'' Merxm. * ''Nicotiana alata'' Johann Heinrich Friedrich Lin ...
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Pipe Smoking
Pipe smoking is the practice of tasting (or, less commonly, inhaling) the smoke produced by burning a substance, most commonly tobacco or cannabis, in a pipe. It is the oldest traditional form of smoking. Regular pipe smoking is known to carry serious health risks including increased danger of various forms of cancer as well as pulmonary and cardiovascular illnesses. History A number of Native American cultures have pipe-smoking traditions, which have been part of their cultures since long before the arrival of Europeans. Tobacco is often smoked, generally for ceremonial purposes, though other mixtures of sacred herbs are also common. Various types of ceremonial pipes have been smoked in ceremony to seal covenants and treaties, most notably treaties of peace (hence the misnomer, " peace pipe"). Tobacco was introduced to Europe from the Americas in the sixteenth century and spread around the world rapidly. In Asia during the nineteenth century, opium (which previously had on ...
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Health Effects Of Tobacco
Tobacco products, especially when smoked or used orally, have serious negative effects on human health. Smoking and smokeless tobacco use are the single greatest causes of preventable death globally. Half of tobacco users die from complications related to such use. Current smokers are estimated to die an average of 10 years earlier than non-smokers. The World Health Organization estimates that, in total, about 8 million people die from tobacco-related causes, including 1.3 million non-smokers due to secondhand smoke. It is further estimated to have caused 100 million deaths in the 20th century. Tobacco smoke contains over List of cigarette smoke carcinogens, 70 chemicals, known as carcinogens, that cause cancer. It also contains nicotine, a highly Addiction, addictive psychoactive drug. When tobacco is smoked, the nicotine causes Physical dependence, physical and psychological dependency. Cigarettes sold in least developed countries have higher tar content and are less likely to ...
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Lung
The lungs are the primary Organ (biology), organs of the respiratory system in many animals, including humans. In mammals and most other tetrapods, two lungs are located near the Vertebral column, backbone on either side of the heart. Their function in the respiratory system is to extract oxygen from the atmosphere and transfer it into the bloodstream, and to release carbon dioxide from the bloodstream into the atmosphere, in a process of gas exchange. Respiration is driven by different muscular systems in different species. Mammals, reptiles and birds use their musculoskeletal systems to support and foster breathing. In early tetrapods, air was driven into the lungs by the pharyngeal muscles via buccal pumping, a mechanism still seen in amphibians. In humans, the primary muscle that drives breathing is the Thoracic diaphragm, diaphragm. The lungs also provide airflow that makes Animal communication#Auditory, vocalisation including speech possible. Humans have two lungs, a ri ...
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Liver
The liver is a major metabolic organ (anatomy), organ exclusively found in vertebrates, which performs many essential biological Function (biology), functions such as detoxification of the organism, and the Protein biosynthesis, synthesis of various proteins and various other Biochemistry, biochemicals necessary for digestion and growth. In humans, it is located in the quadrants and regions of abdomen, right upper quadrant of the abdomen, below the thoracic diaphragm, diaphragm and mostly shielded by the lower right rib cage. Its other metabolic roles include carbohydrate metabolism, the production of a number of hormones, conversion and storage of nutrients such as glucose and glycogen, and the decomposition of red blood cells. Anatomical and medical terminology often use the prefix List of medical roots, suffixes and prefixes#H, ''hepat-'' from ἡπατο-, from the Greek language, Greek word for liver, such as hepatology, and hepatitis The liver is also an accessory digestive ...
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Heart
The heart is a muscular Organ (biology), organ found in humans and other animals. This organ pumps blood through the blood vessels. The heart and blood vessels together make the circulatory system. The pumped blood carries oxygen and nutrients to the tissue, while carrying metabolic waste such as carbon dioxide to the lungs. In humans, the heart is approximately the size of a closed fist and is located between the lungs, in the middle compartment of the thorax, chest, called the mediastinum. In humans, the heart is divided into four chambers: upper left and right Atrium (heart), atria and lower left and right Ventricle (heart), ventricles. Commonly, the right atrium and ventricle are referred together as the right heart and their left counterparts as the left heart. In a healthy heart, blood flows one way through the heart due to heart valves, which prevent cardiac regurgitation, backflow. The heart is enclosed in a protective sac, the pericardium, which also contains a sma ...
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Little, Brown And Company
Little, Brown and Company is an American publishing company founded in 1837 by Charles Coffin Little and James Brown in Boston. For close to two centuries, it has published fiction and nonfiction by American authors. Early lists featured Emily Dickinson's poetry and '' Bartlett's Familiar Quotations''. Since 2006, Little, Brown and Company is a division of the Hachette Book Group. History 19th century Little, Brown and Company had its roots in the book selling trade. It was founded in 1837 in Boston by Charles Little and James Brown. They formed the partnership "for the purpose of Publishing, Importing, and Selling Books". It can trace its roots before that to 1784 to a bookshop owned by Ebenezer Battelle on Marlborough Street. They published works of Benjamin Franklin and George Washington, and specialized in legal publishing and importing titles. The company was the most extensive law publisher in the United States, and also the largest importer of standard English law an ...
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Harmala Alkaloid
Harmala alkaloids are several alkaloids that act as monoamine oxidase inhibitors (MAOIs). These alkaloids are found in the seeds of ''Peganum harmala'' (also known as harmal or Syrian rue), as well as ''Banisteriopsis caapi'' (ayahuasca), leaves of tobacco and coffee beans. The alkaloids include harmine, harmaline, harmalol, and their derivatives, which have similar chemical structures, hence the name "harmala alkaloids". These alkaloids are of interest for their use in Amazonian shamanism, where they are derived from other plants. Harmine, once known as telepathine and banisterine, is a naturally occurring substituted β-carboline, β-carboline alkaloid that is structurally related to harmaline, and also found in the vine ''Banisteriopsis caapi''. Tetrahydroharmine is also found in ''B. caapi'' and ''P. harmala''. Dr. Alexander Shulgin has suggested that harmine may be a breakdown product of harmaline. Harmine and harmaline are reversible inhibitors of monoamine oxidase A (RIMA ...
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Nicotine
Nicotine is a natural product, naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and ''Duboisia hopwoodii'') and is widely used recreational drug use, recreationally as a stimulant and anxiolytic. As a pharmaceutical drug, it is used for smoking cessation to relieve drug withdrawal, withdrawal symptoms. Nicotine acts as a receptor agonist at most nicotinic acetylcholine receptors (nAChRs), except at two nicotinic receptor subunits (nAChRα9 and nAChRα10) where it acts as a receptor antagonist. Nicotine constitutes approximately 0.6–3.0% of the dry weight of tobacco. Nicotine is also present at Parts-per notation, ppb concentrations in edible plants in the family Solanaceae, including potatoes, tomatoes, and eggplants, though sources disagree on whether this has any biological significance to human consumers. It functions as an plant defense against herbivory, antiherbivore toxin; consequently, nicotine was widely used as an insecti ...
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Stimulant
Stimulants (also known as central nervous system stimulants, or psychostimulants, or colloquially as uppers) are a class of drugs that increase alertness. They are used for various purposes, such as enhancing attention, motivation, cognition, Mood disorder, mood, and physical activity, physical performance. Some stimulants occur naturally, while others are exclusively synthetic. Common stimulants include caffeine, nicotine, amphetamines, cocaine, methylphenidate, and modafinil. Stimulants may be subject to varying forms of regulation, or outright prohibition, depending on jurisdiction. Stimulants increase activity in the sympathetic nervous system, either directly or indirectly. Prototypical stimulants increase synaptic concentrations of neurotransmitter, excitatory neurotransmitters, particularly norepinephrine and dopamine (e.g., methylphenidate). Other stimulants work by binding to the Receptor (biochemistry), receptors of excitatory neurotransmitters (e.g., nicotine) or by ...
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Snus
Snus (, ; ) is a Swedish smokeless tobacco, tobacco product. It is consumed by placing a pouch of powdered tobacco leaves under the lip for nicotine to be absorbed through the Mucous membrane, oral mucosa. Snus, not to be confused with Nicotine pouch, nicotine pouches, consists of ground up tobacco leaves, salt, an alkalizer (e.g. sodium carbonate, sodium bicarbonate) and (optionally) flavorings. The final product is sold as both loose tobacco, and in portions with the tobacco mixture contained in a small teabag-like pouch. The manufacturing process of snus differs from that of other oral tobacco products. Snus tobacco is heated and pasteurized rather than cured or fermented, resulting in a less harmful product which contains a lower concentration of TSNA carcinogens in comparison to other traditional tobacco products. Though research on the connection between snus and disease such as cancer is not conclusive, and some studies find no associations between snus consumptio ...
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Dipping Tobacco
Dipping tobacco is a type of finely ground or shredded, moistened smokeless tobacco product. It is commonly and idiomatically known as ''dip''. Dipping tobacco is used by placing a pinch, or "dip", of tobacco between the lip and the gum (sublabial administration). The act of using it is called ''dipping''. Dipping tobacco is colloquially called ''chaw'', ''snuff'', ''rub'', or ''fresh leaf'' among other terms; because of this, it is sometimes confused with other tobacco products—namely dry snuff. Using dipping tobacco can cause various harmful effects such as oral, oesophageal, and pancreatic cancers, coronary heart disease, as well as negative reproductive effects including stillbirth, premature birth and low birth weight. Dipping tobacco poses a lower health risk than traditional combusted products, however, it is not a healthy alternative to cigarette smoking. The level of risk varies between different types of products and producing regions. There is no safe level of d ...
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