Symphytum Officinale
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Symphytum Officinale
''Symphytum officinale'' is a perennial flowering plant in the family Boraginaceae. Along with thirty four other species of ''Symphytum'', it is known as comfrey. To differentiate it from other members of the genus ''Symphytum'', this species is known as common comfrey or true comfrey. Other English names include Quaker comfrey, cultivated comfrey, boneset, knitbone, consound, and slippery-root. It is native to Europe, growing in damp, grassy places. It is locally frequent throughout Ireland and Britain on river banks and ditches. It occurs elsewhere, including North America, as an introduced species and sometimes a weed. The flowers are mostly visited by bumblebees. Internal or long-term topical use of comfrey is discouraged due to its strong potential to cause liver toxicity. History Over centuries, comfrey was cultivated in Asia, Europe, and the United Kingdom as a vegetable and herbal medicine. Its early common names, ''knitbone'' or ''boneset'', reflect its historical us ...
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Carl Linnaeus
Carl Linnaeus (; 23 May 1707 – 10 January 1778), also known after his Nobility#Ennoblement, ennoblement in 1761 as Carl von Linné#Blunt, Blunt (2004), p. 171. (), was a Swedish botanist, zoologist, taxonomist, and physician who formalised binomial nomenclature, the modern system of naming organisms. He is known as the "father of modern Taxonomy (biology), taxonomy". Many of his writings were in Latin; his name is rendered in Latin as and, after his 1761 ennoblement, as . Linnaeus was born in Råshult, the countryside of Småland, in southern Sweden. He received most of his higher education at Uppsala University and began giving lectures in botany there in 1730. He lived abroad between 1735 and 1738, where he studied and also published the first edition of his ' in the Netherlands. He then returned to Sweden where he became professor of medicine and botany at Uppsala. In the 1740s, he was sent on several journeys through Sweden to find and classify plants and animals. In ...
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Traditional Medicine
Traditional medicine (also known as indigenous medicine or folk medicine) comprises medical aspects of traditional knowledge that developed over generations within the folk beliefs of various societies, including indigenous peoples, before the era of modern medicine. The World Health Organization (WHO) defines traditional medicine as "the sum total of the knowledge, skills, and practices based on the theories, beliefs, and experiences indigenous to different cultures, whether explicable or not, used in the maintenance of health as well as in the prevention, diagnosis, improvement or treatment of physical and mental illness". Traditional medicine is often contrasted with scientific medicine. In some Asian and African countries, up to 80% of the population relies on traditional medicine for their primary health care needs. When adopted outside its traditional culture, traditional medicine is often considered a form of alternative medicine. Practices known as traditional medici ...
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Demulcents
A demulcent (derived from the la, demulcere "caress") is a Mucilage, mucilaginous or oleaginous preparation that forms a soothing protective film over a mucous membrane, relieving minor pain and inflammation of the membrane. However, they generally help for less than 30 minutes. Demulcents are sometimes referred to as mucoprotective agents. Demulcents such as pectin, glycerin, honey, and syrup are common ingredients in cough mixtures and cough drops. Examples Natural demulcents include Ulmus rubra, slippery elm, pectin, licorice-root and marsh-mallow. Synthetic demulcents include methylcellulose, propylene glycol, and glycerin. References Further reading External links

* Demulcents, {{Pharma-stub ...
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Symphytum
''Symphytum'' is a genus of flowering plants in the borage family, Boraginaceae, known by the common name comfrey (pronounced ). There are 59 recognized species.WFO (2022): Symphytum L. Published on the Internet; http://www.worldfloraonline.org/taxon/wfo-4000037231. Accessed on: 14 Dec 2022 Some species and hybrids, particularly '' S. officinale'', ''Symphytum grandiflorum'', and ''S.'' × ''uplandicum'', are used in gardening and herbal medicine. They are not to be confused with ''Andersonglossum virginianum'', known as wild comfrey, another member of the borage family. Species Species include: *''Symphytum asperum'' – prickly comfrey, rough comfrey *''Symphytum bulbosum'' – bulbous comfrey *''Symphytum brachycalyx'' - Palestine comfrey *'' Symphytum caucasicum'' – Caucasian comfrey *''Symphytum grandiflorum'' – creeping comfrey *''Symphytum ibericum'' – Iberian comfrey *'' Symphytum officinale'' – comfrey *''Symphytum orientale'' – white comfrey *''Symphytum ta ...
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Drug Development
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug. The entire process – from concept through preclinical testing in the laboratory to clinical trial development, including Phase I–III trials – to approved vaccine or drug typically takes more than a decade. New chemical entity development Broadly, the process of drug development can be divided into preclinical and clinical work. Pre-clinical New chemical entities (NCEs, also known as new molecular entities or NMEs) are compounds that emerge from the process of drug discovery. Th ...
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Livestock
Livestock are the domesticated animals raised in an agricultural setting to provide labor and produce diversified products for consumption such as meat, eggs, milk, fur, leather, and wool. The term is sometimes used to refer solely to animals who are raised for consumption, and sometimes used to refer solely to farmed ruminants, such as cattle, sheep, goats and pigs. Horses are considered livestock in the United States. The USDA classifies pork, veal, beef, and lamb (mutton) as livestock, and all livestock as red meat. Poultry and fish are not included in the category. The breeding, maintenance, slaughter and general subjugation of livestock, called '' animal husbandry'', is a part of modern agriculture and has been practiced in many cultures since humanity's transition to farming from hunter-gatherer lifestyles. Animal husbandry practices have varied widely across cultures and time periods. It continues to play a major economic and cultural role in numerous communities. ...
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Federal Trade Commission
The Federal Trade Commission (FTC) is an independent agency of the United States government whose principal mission is the enforcement of civil (non-criminal) antitrust law and the promotion of consumer protection. The FTC shares jurisdiction over federal civil antitrust enforcement with the Department of Justice Antitrust Division. The agency is headquartered in the Federal Trade Commission Building in Washington, DC. The FTC was established in 1914 with the passage of the Federal Trade Commission Act, signed in response to the 19th-century monopolistic trust crisis. Since its inception, the FTC has enforced the provisions of the Clayton Act, a key antitrust statute, as well as the provisions of the FTC Act, et seq. Over time, the FTC has been delegated with the enforcement of additional business regulation statutes and has promulgated a number of regulations (codified in Title 16 of the Code of Federal Regulations). The broad statutory authority granted to the FTC prov ...
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Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not d ...
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Pyrrolizidine Alkaloid
Pyrrolizidine alkaloids (PAs), sometimes referred to as necine bases, are a group of naturally occurring alkaloids based on the structure of pyrrolizidine. Pyrrolizidine alkaloids are produced by plants as a defense mechanism against insect herbivores. More than 660 PAs and PA N-oxides have been identified in over 6,000 plants, and about half of them exhibit hepatotoxicity. They are found frequently in plants in the Boraginaceae, Asteraceae, Orchidaceae and Fabaceae families; less frequently in the Convolvulaceae and Poaceae, and in at least one species in the Lamiaceae. It has been estimated that 3% of the world’s flowering plants contain pyrrolizidine alkaloids. Honey can contain pyrrolizidine alkaloids, as can grains, milk, offal and eggs. To date (2011), there is no international regulation of PAs in food, unlike those for herbs and medicines. Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic veno-occlusive d ...
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Possett
A posset (also historically spelled poshote, poshotte) was originally a popular British hot drink made of milk curdled with wine or ale, often spiced, which was often used as a remedy. The original drink became extinct and the name was revived in the 19th century and applied to a cream, sugar and citrus-based confection, which is consumed today as a cold set dessert nearly indistinguishable from syllabub. Introduction To make the drink, milk was heated to a boil, then mixed with wine or ale, which curdled it, and the mixture was usually spiced with nutmeg and cinnamon. It was considered a specific remedy for some minor illnesses, such as a cold, and a general remedy for others, as even today people drink hot milk to help them get to sleep. History The OED traces the word to the 15th century: various Latin vocabularies translate ''balducta'', ''bedulta'', or ''casius'' as "poshet", "poshoote", "possyt", or "possot". Russell's ''Boke of Nurture'' (c. 1460) lists variou ...
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John Gerard
John Gerard (also John Gerarde, c. 1545–1612) was an English herbalist with a large garden in Holborn, now part of London. His 1,484-page illustrated ''Herball, or Generall Historie of Plantes'', first published in 1597, became a popular gardening and herbal book in English in the 17th century. Except for some added plants from his own garden and from North America, Gerard's ''Herbal'' is largely a plagiarized English translation of Rembert Dodoens's 1554 herbal, itself highly popular in Dutch, Latin, French and other English translations. Gerard's ''Herball'' drawings of plants and the printer's woodcuts are mainly derived from Continental European sources, but there is an original title page with a copperplate engraving by William Rogers. Two decades after Gerard's death, the book was corrected and expanded to about 1,700 pages. Life Early life and education Gerard was born at Nantwich, Cheshire, towards the end of 1545, receiving his only schooling at nearby Willaston, a ...
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Osteoarthritis
Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone which affects 1 in 7 adults in the United States. It is believed to be the fourth leading cause of disability in the world. The most common symptoms are joint pain and stiffness. Usually the symptoms progress slowly over years. Initially they may occur only after exercise but can become constant over time. Other symptoms may include joint swelling, decreased range of motion, and, when the back is affected, weakness or numbness of the arms and legs. The most commonly involved joints are the two near the ends of the fingers and the joint at the base of the thumbs; the knee and hip joints; and the joints of the neck and lower back. Joints on one side of the body are often more affected than those on the other. The symptoms can interfere with work and normal daily activities. Unlike some other types of arthritis, only the joints, not internal organs, are af ...
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