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Sarah Murnaghan Lung Transplant Controversy
The Sarah Murnaghan lung transplant controversy began in late May 2013, when the parents of a ten-year-old Philadelphia area girl with cystic fibrosis, Sarah Murnaghan, launched a campaign to change the under-12 policy of the United Network for Organ Sharing (UNOS), which they asserted was age discrimination. Her plight received considerable media attention, particularly because Kathleen Sebelius, Secretary of Health and Human Services, refused to intervene to grant an exception to the rule. Background The system organizing lung transplants in the United States was overhauled in 2004 and again in 2008. The system gives those over the age of twelve a lung allocation score, which is used to prioritize patients for transplant based partially on the urgency of their need. However, children under twelve are granted lungs on a first-come, first-served basis. In addition, there are far fewer donor lungs available for children under the age of twelve than there are for adults between 10 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philadelphia
Philadelphia, often called Philly, is the List of municipalities in Pennsylvania#Municipalities, largest city in the Commonwealth (U.S. state), Commonwealth of Pennsylvania, the List of United States cities by population, sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic (United States), Mid-Atlantic regions after New York City. Act of Consolidation, 1854, Since 1854, the city has been coextensive with Philadelphia County, Pennsylvania, Philadelphia County, the List of counties in Pennsylvania, most populous county in Pennsylvania and the urban core of the Delaware Valley, the Metropolitan statistical area, nation's seventh-largest and one of List of largest cities, world's largest metropolitan regions, with 6.245 million residents . The city's population at the 2020 United States census, 2020 census was 1,603,797, and over 56 million people live within of Philadelphia. Philadelphia was founded in 1682 by William Penn, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organ Procurement And Transplantation Network
The United Network for Organ Sharing (UNOS) is a non-profit, scientific and educational organization that administers the only Organ Procurement and Transplantation Network (OPTN) in the United States, established () by the U.S. Congress in 1984 by Gene A. Pierce, founder of United Network for Organ Sharing. Located in Richmond, Virginia, the organization's headquarters are situated near the intersection of Interstate 95 and Interstate 64 in the Virginia BioTechnology Research Park. Activities United Network for Organ Sharing is involved in many aspects of the organ transplant and donation process: * Managing the national transplant waiting list, matching donors to recipients. * Maintaining the database that contains all organ transplant data for every transplant event that occurs in the U.S. * Bringing together members to develop policies that make the best use of the limited supply of organs and give all patients a fair chance at receiving the organ they need, regardless of age ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2013 In Pennsylvania
Thirteen or 13 may refer to: * 13 (number), the natural number following 12 and preceding 14 * One of the years 13 BC, AD 13, 1913, 2013 Music * 13AD (band), an Indian classic and hard rock band Albums * ''13'' (Black Sabbath album), 2013 * ''13'' (Blur album), 1999 * ''13'' (Borgeous album), 2016 * ''13'' (Brian Setzer album), 2006 * ''13'' (Die Ärzte album), 1998 * ''13'' (The Doors album), 1970 * ''13'' (Havoc album), 2013 * ''13'' (HLAH album), 1993 * ''13'' (Indochine album), 2017 * ''13'' (Marta Savić album), 2011 * ''13'' (Norman Westberg album), 2015 * ''13'' (Ozark Mountain Daredevils album), 1997 * ''13'' (Six Feet Under album), 2005 * ''13'' (Suicidal Tendencies album), 2013 * ''13'' (Solace album), 2003 * ''13'' (Second Coming album), 2003 * ''13'' (Ces Cru EP), 2012 * ''13'' (Denzel Curry EP), 2017 * ''Thirteen'' (CJ & The Satellites album), 2007 * ''Thirteen'' (Emmylou Harris album), 1986 * ''Thirteen'' (Harem Scarem album), 2014 * ''Thirt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lung
The lungs are the primary organs of the respiratory system in humans and most other animals, including some snails and a small number of fish. In mammals and most other vertebrates, two lungs are located near the backbone on either side of the heart. Their function in the respiratory system is to extract oxygen from the air and transfer it into the bloodstream, and to release carbon dioxide from the bloodstream into the atmosphere, in a process of gas exchange. Respiration is driven by different muscular systems in different species. Mammals, reptiles and birds use their different muscles to support and foster breathing. In earlier tetrapods, air was driven into the lungs by the pharyngeal muscles via buccal pumping, a mechanism still seen in amphibians. In humans, the main muscle of respiration that drives breathing is the diaphragm. The lungs also provide airflow that makes vocal sounds including human speech possible. Humans have two lungs, one on the left an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organ Transplantation
Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The donor and recipient may be at the same location, or organs may be transported from a donor site to another location. Organs and/or tissues that are transplanted within the same person's body are called autografts. Transplants that are recently performed between two subjects of the same species are called allografts. Allografts can either be from a living or cadaveric source. Organs that have been successfully transplanted include the heart, kidneys, liver, lungs, pancreas, intestine, thymus and uterus. Tissues include bones, tendons (both referred to as musculoskeletal grafts), corneae, skin, heart valves, nerves and veins. Worldwide, the kidneys are the most commonly transplanted organs, followed by the liver and then the heart. Corneae and musculoskeletal grafts are the most commonly transplanted tissue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cystic Fibrosis
Cystic fibrosis (CF) is a rare genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections. Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males. Different people may have different degrees of symptoms. Cystic fibrosis is inherited in an autosomal recessive manner. It is caused by the presence of mutations in both copies of the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Those with a single working copy are carriers and otherwise mostly healthy. CFTR is involved in the production of sweat, digestive fluids, and mucus. When the CFTR is not functional, secretions which are usually thin instead become thick. The condition is diagnosed by a sweat test and genetic testing. Screening of infants at birth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Minimum Ages
In mathematical analysis, the maxima and minima (the respective plurals of maximum and minimum) of a function, known collectively as extrema (the plural of extremum), are the largest and smallest value of the function, either within a given range (the ''local'' or ''relative'' extrema), or on the entire domain (the ''global'' or ''absolute'' extrema). Pierre de Fermat was one of the first mathematicians to propose a general technique, adequality, for finding the maxima and minima of functions. As defined in set theory, the maximum and minimum of a set are the greatest and least elements in the set, respectively. Unbounded infinite sets, such as the set of real numbers, have no minimum or maximum. Definition A real-valued function ''f'' defined on a domain ''X'' has a global (or absolute) maximum point at ''x''∗, if for all ''x'' in ''X''. Similarly, the function has a global (or absolute) minimum point at ''x''∗, if for all ''x'' in ''X''. The value of the function at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioethics
Bioethics is both a field of study and professional practice, interested in ethical issues related to health (primarily focused on the human, but also increasingly includes animal ethics), including those emerging from advances in biology, medicine and technologies. It proposes the discussion about moral discernment in society (what decisions are "good" or "bad" and why) and it is often related to medical policy and practice, but also to broader questions as environment, well-being and public health. Bioethics is concerned with the ethical questions that arise in the relationships among life sciences, biotechnology, medicine, politics, law, theology and philosophy. It includes the study of values relating to primary care, other branches of medicine ( "the ethics of the ordinary"), ethical education in science, animal, and environmental ethics, and public health. Etymology The term ''Bioethics'' (Greek , life; , behavior) was coined in 1927 by Fritz Jahr in an article about ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Compression Fracture
A compression fracture is a collapse of a vertebra. It may be due to trauma or due to a weakening of the vertebra (compare with burst fracture). This weakening is seen in patients with osteoporosis or osteogenesis imperfecta, lytic lesions from metastatic or primary tumors, or infection. In healthy patients, it is most often seen in individuals suffering extreme vertical shocks, such as ejecting from an ejection seat. Seen in lateral views in plain x-ray films, compression fractures of the spine characteristically appear as ''wedge deformities'', with greater loss of height anteriorly than posteriorly and intact pedicles in the anteroposterior view. Signs and symptoms Acute fractures will cause severe back pain. Compression fractures which develop gradually, such as in osteoporosis, may initially not cause any symptoms, but will later often lead to back pain and loss of height. Diagnosis Compression fractures are usually diagnosed on spinal radiographs, where a wedge-shaped ve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Children's Hospital Of Philadelphia
The Children's Hospital of Philadelphia (CHOP) is a children's hospital in Philadelphia, Pennsylvania, with its primary campus located in the University City neighborhood of West Philadelphia in the campus of the University of Pennsylvania. The hospital has 594 beds and more than 1 million outpatient and inpatient visits each year. It is one of the largest and oldest children's hospitals in the world, and United States' first hospital dedicated to the healthcare of children. CHOP has been ranked as the best children's hospital in the United States by '' U.S. News & World Report'' and ''Parents Magazine'' in recent years. As of 2020, it was ranked number one in the nation by U.S. News for three out of ten specialties. The hospital treats infants, children, teens, and young adults aged 0–21. The hospital also treats adults that would benefit from advanced pediatric care. The hospital is located next to the University of Pennsylvania and its physicians serve as the pediatrics dep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nissen Fundoplication
A Nissen fundoplication, or laparoscopic Nissen fundoplication when performed via laparoscopic surgery, is a surgical procedure to treat gastroesophageal reflux disease (GERD) and hiatal hernia. In GERD, it is usually performed when medical therapy has failed; but, with a Type II (paraesophageal) hiatus hernia, it is the first-line procedure. The Nissen fundoplication is total (360°), but partial fundoplications known as Thal (270° anterior), Belsey (270° anterior transthoracic), Dor (anterior 180–200°), Lind (300° posterior), and Toupet fundoplications (posterior 270°) are alternative procedures with somewhat different indications and outcomes. History Dr. Rudolph Nissen (1896–1981) first performed the procedure in 1955 and published the results of two cases in a 1956 ''Swiss Medical Weekly''. In 1961 he published a more detailed overview of the procedure. Nissen originally called the surgery "gastroplication". The procedure has borne his name since it gained popula ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diaphragm Plication
Congenital diaphragmatic hernia (CDH) is a birth defect of the diaphragm. The most common type of CDH is a Bochdalek hernia; other types include Morgagni hernia, diaphragm eventration and central tendon defects of the diaphragm. Malformation of the diaphragm allows the abdominal organs to push into the chest cavity, hindering proper lung formation. CDH is a life-threatening pathology in infants and a major cause of death due to two complications: pulmonary hypoplasia and pulmonary hypertension. Experts disagree on the relative importance of these two conditions, with some focusing on hypoplasia, others on hypertension. Newborns with CDH often have severe respiratory distress which can be life-threatening unless treated appropriately. Classification Bochdalek hernia The Bochdalek hernia, also known as a postero-lateral diaphragmatic hernia, is the most common manifestation of CDH, accounting for more than 95% of cases. In this instance the diaphragm abnormality is characte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
