Richard J. Roberts
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Richard J. Roberts
Sir Richard John Roberts (born 6 September 1943) is a British biochemist and molecular biology, molecular biologist. He was awarded the 1993 Nobel Prize in Physiology or Medicine with Phillip Allen Sharp for the discovery of introns in eukaryote, eukaryotic DNA and the mechanism of Genetic engineering, gene-splicing. He currently works at New England Biolabs. Early life and education Roberts was born in Derby, the son of Edna (Allsop) and John Roberts, an auto mechanic. When he was four, Roberts' family moved to Bath, Somerset, Bath. In Bath, he attended City of Bath Boys' School. As a child he at first wanted to be a detective and then, when given a chemistry set, a chemist. In 1965 he graduated from the University of Sheffield with a Bachelor of Science degree in Chemistry followed by a PhD in 1969. His thesis involved phytochemical studies of neoflavonoids and isoflavonoids.Richard J. Roberts Career and research During 1969–1972, he did postdoctoral research at Harvard U ...
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Oxford University Press
Oxford University Press (OUP) is the university press of the University of Oxford. It is the largest university press in the world, and its printing history dates back to the 1480s. Having been officially granted the legal right to print books by decree in 1586, it is the second oldest university press after Cambridge University Press. It is a department of the University of Oxford and is governed by a group of 15 academics known as the Delegates of the Press, who are appointed by the vice-chancellor of the University of Oxford. The Delegates of the Press are led by the Secretary to the Delegates, who serves as OUP's chief executive and as its major representative on other university bodies. Oxford University Press has had a similar governance structure since the 17th century. The press is located on Walton Street, Oxford, opposite Somerville College, in the inner suburb of Jericho. For the last 500 years, OUP has primarily focused on the publication of pedagogical texts and ...
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Nobel Prize In Physiology Or Medicine
The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according to Alfred Nobel's 1895 will, are awarded "to those who, during the preceding year, have conferred the greatest benefit to humankind". Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace. The Nobel Prize is presented annually on the anniversary of Alfred Nobel's death, 10 December. As of 2022, 114 Nobel Prizes in Physiology or Medicine have been awarded to 226 laureates, 214 men and 12 women. The first one was awarded in 1901 to the German physiologist, Emil von Behring, for his work on serum therapy and the development of a vaccine against diphtheria. The first woman to receive the Nobel Prize in Physiology or Medicine, Gerty Cori, received it in 1947 for her role in elucidati ...
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Detective
A detective is an investigator, usually a member of a law enforcement agency. They often collect information to solve crimes by talking to witnesses and informants, collecting physical evidence, or searching records in databases. This leads them to arrest criminals and enable them to be convicted in court. A detective may work for the police or privately. Overview Informally, and primarily in fiction, a detective is a licensed or unlicensed person who solves crimes, including historical crimes, by examining and evaluating clues and personal records in order to uncover the identity and/or whereabouts of criminals. In some police departments, a detective position is achieved by passing a written test after a person completes the requirements for being a police officer. In many other police systems, detectives are college graduates who join directly from civilian life without first serving as uniformed officers. Some argue that detectives do a completely different job and th ...
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City Of Bath Boys' School
Beechen Cliff School is a boys' secondary school in Bath, Somerset, England, with about 1,150 pupils. Its earliest predecessor school was founded in 1896. There are around 930 boys in years 7 to 11 and a co-educational sixth form of 402 pupils. The school offers the option of state boarding. It is located just south of the city centre near Alexandra Park, up a hill from Bear Flat on the A367, a major route from the south of the city into Bath. History The school began in 1896 as Bath City Secondary School in the Guildhall. It moved from the Guildhall Technical College to its present site at Beechen Cliff in 1932 when it was renamed the City of Bath Boys' School. It changed to its present name in 1970 when the City of Bath reorganised secondary education. The grammar school was amalgamated with Oldfield Boys' School, a local secondary modern school founded in 1903, to form a comprehensive school. On 7 August 1988, on a school climbing expedition in the Briançon region o ...
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Bath, Somerset
Bath () is a city in the Bath and North East Somerset unitary area in the county of Somerset, England, known for and named after its Roman-built baths. At the 2021 Census, the population was 101,557. Bath is in the valley of the River Avon, west of London and southeast of Bristol. The city became a World Heritage Site in 1987, and was later added to the transnational World Heritage Site known as the "Great Spa Towns of Europe" in 2021. Bath is also the largest city and settlement in Somerset. The city became a spa with the Latin name ' ("the waters of Sulis") 60 AD when the Romans built baths and a temple in the valley of the River Avon, although hot springs were known even before then. Bath Abbey was founded in the 7th century and became a religious centre; the building was rebuilt in the 12th and 16th centuries. In the 17th century, claims were made for the curative properties of water from the springs, and Bath became popular as a spa town in the Georgian era. ...
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Genetic Engineering
Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA is obtained by either isolating and copying the genetic material of interest using recombinant DNA methods or by artificially synthesising the DNA. A construct is usually created and used to insert this DNA into the host organism. The first recombinant DNA molecule was made by Paul Berg in 1972 by combining DNA from the monkey virus SV40 with the lambda virus. As well as inserting genes, the process can be used to remove, or "knock out", genes. The new DNA can be inserted randomly, or targeted to a specific part of the genome. An organism that is generated through genetic engineering is considered to be genetically modified (GM) an ...
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Eukaryote
Eukaryotes () are organisms whose cells have a nucleus. All animals, plants, fungi, and many unicellular organisms, are Eukaryotes. They belong to the group of organisms Eukaryota or Eukarya, which is one of the three domains of life. Bacteria and Archaea (both prokaryotes) make up the other two domains. The eukaryotes are usually now regarded as having emerged in the Archaea or as a sister of the Asgard archaea. This implies that there are only two domains of life, Bacteria and Archaea, with eukaryotes incorporated among archaea. Eukaryotes represent a small minority of the number of organisms, but, due to their generally much larger size, their collective global biomass is estimated to be about equal to that of prokaryotes. Eukaryotes emerged approximately 2.3–1.8 billion years ago, during the Proterozoic eon, likely as flagellated phagotrophs. Their name comes from the Greek εὖ (''eu'', "well" or "good") and κάρυον (''karyon'', "nut" or "kernel"). Euka ...
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Phillip Allen Sharp
Phillip Allen Sharp (born June 6, 1944) is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for "the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...s from the same DNA sequence". He has been selected to receive the 2015 Othmer Gold Medal. Research Sharp's current research focuses on small RNAs and other types of non-coding RNAs. His laboratory works to identify the target mRNAs of microRNAs (miRNAs), and has discovered a class of miRNAs that are produced from sequences ...
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Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ...
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Biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of "biological chemist." Biochemists also research how certain chemical reactions happen in cells and Tissue (biology), tissues and observe and record the effects of Product (chemistry), products in food additives and Medication, medicines. Biochemist researchers focus on playing and constructing research experiments, mainly for developing new products, updating existing products and analyzing said products. It is also the responsibility of a biochemist to present their research findings and create Grant writing, grant proposals to obtain Funding of science, funds for future research. Biochemists study aspects of the immune system, the expressions of genes, isolating, analyzing, and synthesizing different products, mutations that lead to ca ...
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Lomonosov Gold Medal
The Lomonosov Gold Medal (russian: Большая золотая медаль имени М. В. Ломоносова ''Bol'shaya zolotaya medal' imeni M. V. Lomonosova''), named after Russian scientist and polymath Mikhail Lomonosov, is awarded each year since 1959 for outstanding achievements in the natural sciences and the humanities by the USSR Academy of Sciences and later the Russian Academy of Sciences (RAS). Since 1967, two medals are awarded annually: one to a Russian and one to a foreign scientist. It is the Academy's highest accolade. Recipients of Lomonosov Gold Medal __NOTOC__ 1959 * Pyotr Leonidovich Kapitsa: cumulatively, for works in physics of low temperatures. 1961 * Aleksandr Nikolaevich Nesmeyanov: accumulatively for works in chemistry. 1963 * Sin-Itiro Tomonaga (member of the Japanese academy of Sciences, president of the Scientific Council of Japan): for substantial scientific contributions to the development of physics. * Hideki Yukawa (member of the ...
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Knight Bachelor
The title of Knight Bachelor is the basic rank granted to a man who has been knighted by the monarch but not inducted as a member of one of the organised orders of chivalry; it is a part of the British honours system. Knights Bachelor are the most ancient sort of British knight (the rank existed during the 13th-century reign of King Henry III), but Knights Bachelor rank below knights of chivalric orders. A man who is knighted is formally addressed as "Sir irst Name urname or "Sir irst Name and his wife as "Lady urname. Criteria Knighthood is usually conferred for public service; amongst its recipients are all male judges of His Majesty's High Court of Justice in England. It is possible to be a Knight Bachelor and a junior member of an order of chivalry without being a knight of that order; this situation has become rather common, especially among those recognized for achievements in entertainment. For instance, Sir Michael Gambon, Sir Derek Jacobi, Sir Anthony Hopkins, Sir ...
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