Roland Griffiths
Roland Redmond Griffiths (July 19, 1946 – October 16, 2023) was an American psychopharmacologist. At Johns Hopkins University School of Medicine, he was professor of neuroscience, psychiatry, and Behavioural sciences, behavioral science, and he was the director of the Center for Psychedelic therapy, Psychedelic and Consciousness Research. Life and career Griffiths was born in Glen Cove, New York, on July 19, 1946. His mother was a homemaker, and his father, a psychologist, became a professor at the University of California, Berkeley; Griffiths grew up in El Cerrito, California. He earned his undergraduate degree from Occidental College and his Doctor of Philosophy from the University of Minnesota in psychopharmacology, in 1972. After completing his doctorate, Griffiths joined the faculty of Johns Hopkins University. In 1994, he published research demonstrating the addictive nature of caffeine as well as its drug withdrawal, withdrawal syndrome. Griffiths began studying psych ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Glen Cove, New York
Glen Cove is a city in Nassau County, New York, United States, on the North Shore of Long Island. At the 2020 United States Census, the city population was 28,365 as of the 2020 census. The city was considered part of the early 20th century Gold Coast of the North Shore, as the areas along the waterfront were developed as large country estates by wealthy entrepreneurs and businessmen such as J.P. Morgan, Phipps, Pratt, and Prybil. Glen Cove also had manufacturing and a diverse population that worked in industry, local agriculture and retail businesses. Of Nassau County's five municipalities, Glen Cove is one of the two municipalities that is a city, rather than a town, the other being Long Beach on the South Shore. The city was the location of several successful manufacturing facilities in the 20th century. It attracted numerous immigrants from Ireland, Italy, and eastern Europe. More recently, it has been settled by immigrants of later migrations, from Central and South Am ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Johns Hopkins University
Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hemisphere. It consistently ranks among the most prestigious universities in the United States and the world. The university was named for its first benefactor, the American entrepreneur and Quaker philanthropist Johns Hopkins. Hopkins' $7 million bequest to establish the university was the largest philanthropic gift in U.S. history up to that time. Daniel Coit Gilman, who was inaugurated as Johns Hopkins's first president on February 22, 1876, led the university to revolutionize higher education in the U.S. by integrating teaching and research. In 1900, Johns Hopkins became a founding member of the American Association of Universities. The university has led all U.S. universities in annual research expenditures over the past three decades. Johns Hopkins is ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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2023 Deaths
The following notable deaths occurred in 2023. Names are reported under the date of death, in alphabetical order. A typical entry reports information in the following sequence: * Name, age, country of citizenship at birth, subsequent nationality (if applicable), what subject was noted for, cause of death (if known), and reference. January 18 17 * Jay Briscoe, 38, American professional wrestler (ROH, CZW, NJPW), traffic collision. *Teodor Corban, 65, Romanian actor ('' 12:08 East of Bucharest'', ''4 Months, 3 Weeks and 2 Days'', '' Tales from the Golden Age''). *Manana Doijashvili, 75, Georgian pianist. *Leon Dubinsky, 81, Canadian actor ('' Life Classes'', '' Pit Pony''), theatre director and composer (" Rise Again"). * Renée Geyer, 69, Australian singer (" Say I Love You", " Heading in the Right Direction", " Stares and Whispers"), complications from hip surgery. *, 89, Italian choreographer and television and theatre director. *, 90, Iranian voice actor. * Larry Morr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1946 Births
Events January * January 6 - The first general election ever in Vietnam is held. * January 7 – The Allies recognize the Austrian republic with its 1937 borders, and divide the country into four occupation zones. * January 10 ** The first meeting of the United Nations is held, at Methodist Central Hall Westminster in London. ** ''Project Diana'' bounces radar waves off the Moon, measuring the exact distance between the Earth and the Moon, and proves that communication is possible between Earth and outer space, effectively opening the Space Age. * January 11 - Enver Hoxha declares the People's Republic of Albania, with himself as prime minister. * January 16 – Charles de Gaulle resigns as head of the French provisional government. * January 17 - The United Nations Security Council holds its first session, at Church House, Westminster in London. * January 19 ** The Bell XS-1 is test flown for the first time (unpowered), with Bell's chief test pilot Jack Woolams at the c ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Colon Cancer
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, and fatigue. Most colorectal cancers are due to old age and lifestyle factors, with only a small number of cases due to underlying genetic disorders. Risk factors include diet, obesity, smoking, and lack of physical activity. Dietary factors that increase the risk include red meat, processed meat, and alcohol. Another risk factor is inflammatory bowel disease, which includes Crohn's disease and ulcerative colitis. Some of the inherited genetic disorders that can cause colorectal cancer include familial adenomatous polyposis and hereditary non-polyposis colon cancer; however, these represent less than 5% of cases. It typically starts as a benign tumor, often in the form of a polyp, which over time becomes ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. The newly pathological sites, then, are metastases (mets). It is generally distinguished from cancer invasion, which is the direct extension and penetration by cancer cells into neighboring tissues. Cancer occurs after cells are genetically altered to proliferate rapidly and indefinitely. This uncontrolled proliferation by mitosis produces a primary heterogeneic tumour. The cells which constitute the tumor eventually undergo metaplasia, followed by dysplasia then anaplasia, resulting in a malignant phenotype. This malignancy allows for invasion into the circulation, followed by invasion to a second site for tumorigenesis. Some cancer cells known as circulating tumor cells acquire the ability to penetrate the walls of lymphatic or blood vessels, after which they a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Wayback Machine
The Wayback Machine is a digital archive of the World Wide Web founded by the Internet Archive, a nonprofit based in San Francisco, California. Created in 1996 and launched to the public in 2001, it allows the user to go "back in time" and see how websites looked in the past. Its founders, Brewster Kahle and Bruce Gilliat, developed the Wayback Machine to provide "universal access to all knowledge" by preserving archived copies of defunct web pages. Launched on May 10, 1996, the Wayback Machine had more than 38.2 million records at the end of 2009. , the Wayback Machine had saved more than 760 billion web pages. More than 350 million web pages are added daily. History The Wayback Machine began archiving cached web pages in 1996. One of the earliest known pages was saved on May 10, 1996, at 2:08p.m. Internet Archive founders Brewster Kahle and Bruce Gilliat launched the Wayback Machine in San Francisco, California, in October 2001, primarily to address the problem of we ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Discover (magazine)
''Discover'' is an American general audience science magazine launched in October 1980 by Time Inc. It has been owned by Kalmbach Publishing since 2010. History Founding ''Discover'' was created primarily through the efforts of ''Time'' magazine editor Leon Jaroff. He noticed that magazine sales jumped every time the cover featured a science topic. Jaroff interpreted this as a considerable public interest in science, and in 1971, he began agitating for the creation of a science-oriented magazine. This was difficult, as a former colleague noted, because "Selling science to people who graduated to be managers was very difficult".Hevesi, Dennis"Leon Jaroff, Editor at Time and Discover Magazines, Dies at 85" ''The New York Times'', 21 October 2012 Jaroff's persistence finally paid off, and ''Discover'' magazine published its first edition in 1980. ''Discover'' was originally launched into a burgeoning market for science magazines aimed at educated non-professionals, intended t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Anxiety Disorder
Anxiety disorders are a cluster of mental disorders characterized by significant and uncontrollable feelings of anxiety and fear such that a person's social, occupational, and personal function are significantly impaired. Anxiety may cause physical and cognitive symptoms, such as restlessness, irritability, easy fatiguability, difficulty concentrating, increased heart rate, chest pain, abdominal pain, and a variety of other symptoms that may vary based on the individual. In casual discourse, the words ''anxiety'' and ''fear'' are often used interchangeably. In clinical usage, they have distinct meanings: anxiety is defined as an unpleasant emotional state for which the cause is either not readily identified or perceived to be uncontrollable or unavoidable, whereas fear is an emotional and physiological response to a recognized external threat. The umbrella term ''anxiety disorder'' refers to a number of specific disorders that include fears (phobias) or anxiety symptoms. There a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Major Depressive Disorder
Major depressive disorder (MDD), also known as clinical depression, is a mental disorder characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, the term was adopted by the American Psychiatric Association for this symptom cluster under mood disorders in the 1980 version of the '' Diagnostic and Statistical Manual of Mental Disorders'' (DSM-III), and has become widely used since. The diagnosis of major depressive disorder is based on the person's reported experiences, behavior reported by relatives or friends, and a mental status examination. There is no laboratory test for the disorder, but testing may be done to rule out physical conditions that can cause similar symptoms. The most common time of onset is in a person's 20s, with females affected about twice as often as males. The course of the disorder varies widely, from one e ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Psilocybin
Psilocybin ( , ) is a naturally occurring psychedelic prodrug compound produced by more than 200 species of fungi. The most potent are members of the genus ''Psilocybe'', such as '' P. azurescens'', '' P. semilanceata'', and '' P. cyanescens'', but psilocybin has also been isolated from about a dozen other genera. Psilocybin is itself biologically inactive but is quickly converted by the body to psilocin, which has mind-altering effects similar, in some aspects, to those of LSD, mescaline, and DMT. In general, the effects include euphoria, visual and mental hallucinations, changes in perception, a distorted sense of time, and perceived spiritual experiences. It can also cause adverse reactions such as nausea and panic attacks. Imagery found on prehistoric murals and rock paintings of modern-day Spain and Algeria suggests that human usage of psilocybin mushrooms predates recorded history. In Mesoamerica, the mushrooms had long been consumed in spiritual ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |