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Ommaya Reservoir
An Ommaya reservoir is an intraventricular catheter system that can be used for the aspiration of cerebrospinal fluid or for the delivery of drugs (e.g. chemotherapy) into the cerebrospinal fluid. It consists of a catheter in one lateral ventricle attached to a reservoir implanted under the scalp. It is used to treat brain tumors, leukemia/lymphoma or leptomeningeal disease by intrathecal drug administration. In the palliative care of terminal cancer, an Ommaya reservoir can be inserted for intracerebroventricular injection (ICV) of morphine. It was originally invented in 1963 by Ayub K. Ommaya, a South-Asian-American neurosurgeon. In January 2017, researchers at University of Texas Southwestern Medical Centre used an Ommaya reservoir to measure the intracranial pressure that is regularly observed in astronauts in zero-gravity Weightlessness is the complete or near-complete absence of the sensation of weight. It is also termed zero gravity, zero G-force, or zero-G. Wei ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Catheter
In medicine, a catheter (/ˈkæθətər/) is a thin tubing (material), tube made from medical grade materials serving a broad range of functions. Catheters are medical devices that can be inserted in the body to treat diseases or perform a surgical procedure. Catheters are manufactured for specific applications, such as cardiovascular, urological, gastrointestinal, neurovascular and ophthalmic procedures. The process of inserting a catheter is ''catheterization''. In most uses, a catheter is a thin, flexible tube (''soft'' catheter) though catheters are available in varying levels of stiffness depending on the application. A catheter left inside the body, either temporarily or permanently, may be referred to as an "indwelling catheter" (for example, a peripherally inserted central catheter). A permanently inserted catheter may be referred to as a "permcath" (originally a trademark). Catheters can be inserted into a body cavity, duct, or vessel, brain, skin or adipose tissue. Fun ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurosurgeon
Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the medical specialty concerned with the surgical treatment of disorders which affect any portion of the nervous system including the brain, spinal cord and peripheral nervous system. Education and context In different countries, there are different requirements for an individual to legally practice neurosurgery, and there are varying methods through which they must be educated. In most countries, neurosurgeon training requires a minimum period of seven years after graduating from medical school. United States In the United States, a neurosurgeon must generally complete four years of undergraduate education, four years of medical school, and seven years of residency (PGY-1-7). Most, but not all, residency programs have some component of basic science or clinical research. Neurosurgeons may pursue additional training in the form of a fellowship after residency, or, in some cases, as a senior resid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pakistani Inventions
This article lists inventions and discoveries made by scientists with Pakistani nationality within Pakistan and outside the country, as well as those made in the territorial area of what is now Pakistan prior to the independence of Pakistan in 1947. Bronze Age Indus Valley civilisation *Proto-writing:Indus script was a Bronze Age script developed along Indus river, in modern day's Pakistan. * Button, ornamental: Buttons—made from seashell—were used in the Indus Valley civilization for ornamental purposes by 2000 BCE.Hesse, Rayner W. & Hesse (Jr.), Rayner W. (2007). ''Jewelrymaking Through History: An Encyclopedia''. Greenwood Publishing Group. 35. . Some buttons were carved into geometric shapes and had holes pieced into them so that they could attached to clothing by using a thread. Ian McNeil (1990) holds that: "The button, in fact, was originally used more as an ornament than as a fastening, the earliest known being found at Mohenjo-daro in the Indus Valley. It is ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Delivery Devices
A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via inhalation, injection, smoking, ingestion, absorption via a patch on the skin, suppository, or dissolution under the tongue. In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect. A pharmaceutical drug, also called a medication or medicine, is a chemical substance used to treat, cure, prevent, or diagnose a disease or to promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used for a limited duration, or on a regular basis for chronic disorders. Pharmaceutical drugs are often classified into drug classes—groups of relate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Equipment
A medical device is any device intended to be used for medical purposes. Significant potential for hazards are inherent when using a device for medical purposes and thus medical devices must be proved safe and effective with reasonable assurance before regulating governments allow marketing of the device in their country. As a general rule, as the associated risk of the device increases the amount of testing required to establish safety and efficacy also increases. Further, as associated risk increases the potential benefit to the patient must also increase. Discovery of what would be considered a medical device by modern standards dates as far back as c. 7000 BC in Baluchistan where Neolithic dentists used flint-tipped drills and bowstrings. Study of archeology and Roman medical literature also indicate that many types of medical devices were in widespread use during the time of ancient Rome. In the United States it wasn't until the Federal Food, Drug, and Cosmetic Act (FD&C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science And Technology In Pakistan
Science and technology is a growing field in Pakistan and has played an important role in the country's development since its founding. Pakistan has a large pool of scientists, engineers, doctors, and technicians assuming an active role in science and technology. The real growth in science in Pakistan occurred after the establishment of the Higher education Commission in 2002 which supported science in a big way and also became the major sponsor of the Pakistan Academy of Sciences under the leadership of Prof. Atta-ur-Rahman. The emphasis was placed on quality rather than numbers during this period. The quality measures introduced by Prof. Atta-ur-Rahman as Founding Chairman HEC included:1) All Ph.D. thesis were evaluated by eminent foreign scientists,2) All PhD theses and research papers were checked for plagiarism 3) Some 11,000 students were sent abroad to leading universities for PhD level training and absorbed on their return, 4) Appointments at faculty positions were ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Weightlessness
Weightlessness is the complete or near-complete absence of the sensation of weight. It is also termed zero gravity, zero G-force, or zero-G. Weight is a measurement of the force on an object at rest in a relatively strong gravitational field (such as on the surface of the Earth). These weight-sensations originate from contact with supporting floors, seats, beds, scales, and the like. A sensation of weight is also produced, even when the gravitational field is zero, when contact forces act upon and overcome a body's inertia by mechanical, non-gravitational forces- such as in a centrifuge, a rotating space station, or within an accelerating vehicle. When the gravitational field is non-uniform, a body in free fall experiences tidal effects and is not stress-free. Near a black hole, such tidal effects can be very strong. In the case of the Earth, the effects are minor, especially on objects of relatively small dimensions (such as the human body or a spacecraft) and the overa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intracranial Pressure
Intracranial pressure (ICP) is the pressure exerted by fluids such as cerebrospinal fluid (CSF) inside the skull and on the brain tissue. ICP is measured in millimeters of mercury ( mmHg) and at rest, is normally 7–15 mmHg for a supine adult. The body has various mechanisms by which it keeps the ICP stable, with CSF pressures varying by about 1 mmHg in normal adults through shifts in production and absorption of CSF. Changes in ICP are attributed to volume changes in one or more of the constituents contained in the cranium. CSF pressure has been shown to be influenced by abrupt changes in intrathoracic pressure during coughing (which is induced by contraction of the diaphragm and abdominal wall muscles, the latter of which also increases intra-abdominal pressure), the valsalva maneuver, and communication with the vasculature ( venous and arterial systems). Intracranial hypertension (IH), also called increased ICP (IICP) or raised intracranial pressure (RICP), is elevation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ayub K
Ayub (Arabic: ايّوب ''Ayūb'', commonly written ايوب) is the Arabic name of the Abrahamic prophet Job. Here it refers to the Islamic prophet which is mentioned in the Quran, see Job in Islam. The spread of the name among Muslims is partly due to the fame of Saladin, founder of the Ayyubid dynasty, whose name in Arabic is ''Salạ̄hu d-Dīn Yūsuf ibn Ayūb''. Other people with this given name * Abu Ayyub al-Ansari, a companion (''sahaba'') of Muhammad * Ayub Ali Master, early British-Bangladeshi social reformer, politician and entrepreneur * Ayub Shah Durrani, Afghan ruler * Ayub Khan (1907-1974), second President of Pakistan * Ayub Afridi, Pakistani drug lord turned politician * Ayub Ommaya (1930-2008), a Pakistani neurosurgeon * Ayub Shah Bukhari, Pakistani Sufi * Ayub Thakur (1948-2004), Kashmiri freedom activist * Master Ayub, a Pakistani teacher who runs an open air, free of cost, school in Islamabad since 1986 * Ayub Khan Din (born 1961), British-Pakistani actor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cerebrospinal Fluid
Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates. CSF is produced by specialised ependymal cells in the choroid plexus of the ventricles of the brain, and absorbed in the arachnoid granulations. There is about 125 mL of CSF at any one time, and about 500 mL is generated every day. CSF acts as a shock absorber, cushion or buffer, providing basic mechanical and immunological protection to the brain inside the skull. CSF also serves a vital function in the cerebral autoregulation of cerebral blood flow. CSF occupies the subarachnoid space (between the arachnoid mater and the pia mater) and the ventricular system around and inside the brain and spinal cord. It fills the ventricles of the brain, cisterns, and sulci, as well as the central canal of the spinal cord. There is also a connection from the subarachnoid space to the bony labyrinth of the inner ear via the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intracerebroventricular Injection
Intracerebroventricular injection (also called ICV injection, i.c.v. injection, or sometimes ICVI) is an invasive injection technique of substances directly into the cerebrospinal fluid in cerebral ventricles in order to bypass the bloodbrain barrier. Although this barrier effectively protects the brain, it can prevent important medications from entering the CNS. The technique is widely used in biomedical research to introduce drugs, therapeutic RNAs, plasmid DNAs, and viral vectors into the CNS of diseased mice models. It can also be used in human in cases of neurodegenerative disorders like spinal muscular atrophy (SMA), or administering chemotherapy in gliomas as well as delivering neurotrophic factors to CNS. It can be contrasted with intraperitoneal injection as an alternative choice of route of administration with differing pharmacokinetic and pharmacodynamic effects. The Ommaya reservoir is a catheter system invented by Ayub Ommaya Ayub Khan Ommaya MD, ScD (hc), FRC ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Palliative Care
Palliative care (derived from the Latin root , or 'to cloak') is an interdisciplinary medical caregiving approach aimed at optimizing quality of life and mitigating suffering among people with serious, complex, and often terminal illnesses. Within the published literature, many definitions of palliative care exist. The World Health Organization (WHO) describes palliative care as "an approach that improves the quality of life of patients and their families facing the problems associated with life-threatening illness, through the prevention and relief of suffering by means of early identification and impeccable assessment and treatment of pain and other problems, physical, psychosocial, and spiritual." In the past, palliative care was a disease specific approach, but today the WHO takes a more broad approach, that the principles of palliative care should be applied as early as possible to any chronic and ultimately fatal illness. Palliative care is appropriate for individuals with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
