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Malignant (other)
Malignant refers to malignancy, the tendency of a medical condition to become progressively worse. Malignant may also refer to: *Malignant (2013 film), ''Malignant'' (2013 film), an American horror film directed by Brian Avenet-Bradley *Malignant (2021 film), ''Malignant'' (2021 film), an American horror film directed by James Wan *Malignant (Law & Order: Criminal Intent), "Malignant" (''Law & Order: Criminal Intent''), an episode of ''Law & Order: Criminal Intent'' *''Malignant: How Cancer Becomes Us'', a 2013 book by S. Lochlann Jain See also *Cancer (other) *Tumor {{disambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malignant
Malignancy () is the tendency of a medical condition to become progressively worse. Malignancy is most familiar as a characterization of cancer. A ''malignant'' tumor contrasts with a non-cancerous ''benign'' tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues, and may be capable of spreading to distant tissues. A benign tumor has none of those properties. Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis. Malignant tumors are also characterized by genome instability, so that cancers, as assessed by whole genome sequencing, frequently have between 10,000 and 100,000 mutations in their entire genomes. Cancers usually show tumour heterogeneity, containing multiple subclones. They also frequently have reduced expression of DNA repair enzymes due to epigenetic methylation of DNA repair genes or altered microRNAs that control DNA repair gene expression. Tumours can be detected through the visual ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |