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Lobotomy
A lobotomy, or leucotomy, is a form of neurosurgical treatment for psychiatric disorder or neurological disorder (e.g. epilepsy) that involves severing connections in the brain's prefrontal cortex. The surgery causes most of the connections to and from the prefrontal cortex, the anterior part of the frontal lobes of the brain, to be severed. In the past, this treatment was used for treating psychiatric disorders as a mainstream procedure in some countries. The procedure was controversial from its initial use, in part due to a lack of recognition of the severity and chronicity of severe and enduring psychiatric illnesses, so it was claimed to be an inappropriate treatment. Frontal lobe surgery, including lobotomy, is the second most common surgery for epilepsy to this day, and usually done on one side of the brain, unlike lobotomies for psychiatric disorder which were done on both sides of the brain. The originator of the procedure, Portuguese neurologist António Egas Mon ...
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Walter Jackson Freeman II
Walter Jackson Freeman II (November 14, 1895 – May 31, 1972) was an American physician who specialized in lobotomy. Early years Walter J. Freeman was born on November 14, 1895, and raised in Philadelphia, Pennsylvania, by his parents. Freeman's grandfather, William Williams Keen, was well known as a surgeon in the Civil War. His father was also a very successful doctor. Freeman attended Yale University beginning in 1912, and graduated in 1916. He then moved on to study neurology at the University of Pennsylvania Medical School. While attending medical school, he studied the work of William Spiller and idolized his groundbreaking work in the new field of the neurological sciences. Freeman applied for a coveted position working alongside Spiller in his home town of Philadelphia, but was rejected. Shortly afterward, in 1924, Freeman relocated to Washington, D.C., and started practicing as the first neurologist in the city. Upon his arrival in Washington, Freeman began work direc ...
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António Egas Moniz
António Caetano de Abreu Freire Egas Moniz (29 November 1874 – 13 December 1955), known as Egas Moniz (), was a Portuguese neurologist and the developer of cerebral angiography. He is regarded as one of the founders of modern psychosurgery, having developed the surgical procedure ''leucotomy''better known today as ''lobotomy''for which he became the first Portuguese national to receive a Nobel Prize in 1949 (shared with Walter Rudolf Hess). He held academic positions, wrote many medical articles and also served in several legislative and diplomatic posts in the Portuguese government. In 1911, he became professor of neurology in Lisbon until his retirement in 1944. Early life and training Moniz was born in Avanca, Estarreja, Portugal, as António Caetano de Abreu Freire de Resende. He attended Escola do Padre José Ramos and the Jesuit-run College of Saint Fidelis and studied medicine at the University of Coimbra, graduating in 1899. For the next 12 years, he served as a ...
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Neurosurgery
Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the medical specialty concerned with the surgical treatment of disorders which affect any portion of the nervous system including the brain, spinal cord and peripheral nervous system. Education and context In different countries, there are different requirements for an individual to legally practice neurosurgery, and there are varying methods through which they must be educated. In most countries, neurosurgeon training requires a minimum period of seven years after graduating from medical school. United States In the United States, a neurosurgeon must generally complete four years of undergraduate education, four years of medical school, and seven years of residency (PGY-1-7). Most, but not all, residency programs have some component of basic science or clinical research. Neurosurgeons may pursue additional training in the form of a fellowship after residency, or, in some cases, as a senior res ...
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Frontal Lobe
The frontal lobe is the largest of the four major lobes of the brain in mammals, and is located at the front of each cerebral hemisphere (in front of the parietal lobe and the temporal lobe). It is parted from the parietal lobe by a groove between tissues called the central sulcus and from the temporal lobe by a deeper groove called the lateral sulcus (Sylvian fissure). The most anterior rounded part of the frontal lobe (though not well-defined) is known as the frontal pole, one of the three poles of the cerebrum. The frontal lobe is covered by the frontal cortex. The frontal cortex includes the premotor cortex, and the primary motor cortex – parts of the motor cortex. The front part of the frontal cortex is covered by the prefrontal cortex. There are four principal gyri in the frontal lobe. The precentral gyrus is directly anterior to the central sulcus, running parallel to it and contains the primary motor cortex, which controls voluntary movements of specific body par ...
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Nobel Prize For Physiology Or Medicine
The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according to Alfred Nobel's 1895 will, are awarded "to those who, during the preceding year, have conferred the greatest benefit to humankind". Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace. The Nobel Prize is presented annually on the anniversary of Alfred Nobel's death, 10 December. As of 2022, 114 Nobel Prizes in Physiology or Medicine have been awarded to 226 laureates, 214 men and 12 women. The first one was awarded in 1901 to the German physiologist, Emil von Behring, for his work on serum therapy and the development of a vaccine against diphtheria. The first woman to receive the Nobel Prize in Physiology or Medicine, Gerty Cori, received it in 1947 for her role in elucidating the ...
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Mental Disorders
A mental disorder, also referred to as a mental illness or psychiatric disorder, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning. Such features may be persistent, relapsing and remitting, or occur as single episodes. Many disorders have been described, with signs and symptoms that vary widely between specific disorders. Such disorders may be diagnosed by a mental health professional, usually a clinical psychologist or psychiatrist. The causes of mental disorders are often unclear. Theories may incorporate findings from a range of fields. Mental disorders are usually defined by a combination of how a person behaves, feels, perceives, or thinks. This may be associated with particular regions or functions of the brain, often in a social context. A mental disorder is one aspect of mental health. Cultural and religious beliefs, as well as social norms, should be taken into account when making a diagnosis. Services ...
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Mental Disorder
A mental disorder, also referred to as a mental illness or psychiatric disorder, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning. Such features may be persistent, relapsing and remitting, or occur as single episodes. Many disorders have been described, with signs and symptoms that vary widely between specific disorders. Such disorders may be diagnosed by a mental health professional, usually a clinical psychologist or psychiatrist. The causes of mental disorders are often unclear. Theories may incorporate findings from a range of fields. Mental disorders are usually defined by a combination of how a person behaves, feels, perceives, or thinks. This may be associated with particular regions or functions of the brain, often in a social context. A mental disorder is one aspect of mental health. Cultural and religious beliefs, as well as social norms, should be taken into account when making a diagnosis. Service ...
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Heroic Measure
In medicine, heroic treatment or course of therapy is one which possesses a high risk of causing further damage to a patient's health, but is undertaken as a last resort with the understanding that any lesser treatment will surely result in failure. Heroic measures are often taken in cases of grave injury or illness, as a last-ditch attempt to save life, limb, or eyesight. Examples include emergency trauma surgery conducted outside the operating room (such as "on-scene" surgical amputation, cricothyroidotomy, or thoracotomy), or administration of medication (such as certain antibiotics and chemotherapy drugs) at dosage levels high enough to potentially cause serious or fatal side effects. Cardiopulmonary resuscitation is a particularly well-known heroic measure; vigorous chest compressions often result in fracturing one or more of the patient's ribs, but since the alternative is certain death, the technique is accepted as necessary. Patients with advanced AIDS and concomitant ...
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Therapeutic Nihilism
Therapeutic nihilism is a contention that it is impossible to cure people or societies of their ills through treatment. In medicine, it was connected to the idea that many "cures" do more harm than good, and that one should instead encourage the body to heal itself. Michel de Montaigne espoused this view in his ''Essais'' in 1580. This position was later popular, among other places, in France in the 1820s and 1830s, but has mostly faded away in the modern era due to the development of provably effective medicines such as antibiotics. History Around the late 19th century, therapeutic nihilism gained some prominence among medical professionals. Proponents of this view claimed that every man should be his own physician through democratization of knowledge. Cultural critic Matthew Arnold was quoted as saying that "the stream of tendency of modern medical thought was toward a therapeutic nihilism." The most preferred approach to medicine at the time was what was sometimes called ''a ...
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Electroconvulsive Therapy
Electroconvulsive therapy (ECT) is a psychiatric treatment where a generalized seizure (without muscular convulsions) is electrically induced to manage refractory mental disorders.Rudorfer, MV, Henry, ME, Sackeim, HA (2003)"Electroconvulsive therapy". In A Tasman, J Kay, JA Lieberman (eds) ''Psychiatry, Second Edition''. Chichester: John Wiley & Sons Ltd, 1865–1901. Typically, 70 to 120 volts are applied externally to the patient's head, resulting in approximately 800 milliamperes of direct current passing between the electrodes, for a duration of 100 milliseconds to 6 seconds, either from temple to temple (bilateral ECT) or from front to back of one side of the head (unilateral ECT). However, only about 1% of the electrical current crosses the bony skull into the brain because skull impedance is about 100 times higher than skin impedance. The ECT procedure was first conducted in 1938 by Italian psychiatrist Ugo Cerletti and rapidly replaced less safe and effective forms of ...
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Seizures
An epileptic seizure, informally known as a seizure, is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain. Outward effects vary from uncontrolled shaking movements involving much of the body with loss of consciousness ( tonic-clonic seizure), to shaking movements involving only part of the body with variable levels of consciousness ( focal seizure), to a subtle momentary loss of awareness ( absence seizure). Most of the time these episodes last less than two minutes and it takes some time to return to normal. Loss of bladder control may occur. Seizures may be provoked and unprovoked. Provoked seizures are due to a temporary event such as low blood sugar, alcohol withdrawal, abusing alcohol together with prescription medication, low blood sodium, fever, brain infection, or concussion. Unprovoked seizures occur without a known or fixable cause such that ongoing seizures are likely. Unprovoked seizures may be exacerbated by stress ...
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Ugo Cerletti
Ugo Cerletti (26 September 1877 – 25 July 1963) was an Italian neurologist who discovered the method of electroconvulsive therapy (ECT) used in psychiatry. Electroconvulsive therapy is a therapy in which electric current is used to provoke a seizure for a short duration. This therapy is used in an attempt to treat certain mental disorders, and may be useful when other possible treatments have not, or cannot, cure the person of their mental disorder. Life Ugo Cerletti was born in Conegliano, in the region of Veneto, Italy, on 26 September 1877. He studied Medicine at Rome and Turin, later specializing in neurology and neuropsychiatry. In his early scientific studies, Cerletti mainly focused on common issues in the fields of histology and histopathology. He demonstrated how the nervous tissue reacts to different pathogenic stimuli in its own ways, making the histopathology of nervous tissue an independent category in the study of medicine. As a student, he conducted some research un ...
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