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Karl Adolph Von Basedow
Carl Adolph von Basedow (28 March 1799 – 11 April 1854) was a Germans, German physician most famous for reporting the symptoms of what could later be dubbed Graves-Basedow disease, now technically known as exophthalmic goiter. Biography Basedow was born in Dessau. He graduated from Halle University. He subsequently began general practice in Merseburg in 1822. He married early and became the town's chief medical officer, a position he would hold for the rest of his life. In 1840, Basedow reported on the conditions of what is now called Graves-Basedow disease. He died in Merseburg in 1854 after contracting spotted fever from a corpse he was dissection, dissecting. Medical work Basedow has three eponymous medical conditions: Basedow's coma, a thyreotoxic coma; Basedow's ocular syndromes, the unilateral retraction of the upper lid in Basedow’s syndrome; and, Graves-Basedow disease, a disorder characterized by the "Merseburger triad": tachycardia, goitre, and exophthalmos. Th ...
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Germans
, native_name_lang = de , region1 = , pop1 = 72,650,269 , region2 = , pop2 = 534,000 , region3 = , pop3 = 157,000 3,322,405 , region4 = , pop4 = 21,000 3,000,000 , region5 = , pop5 = 125,000 982,226 , region6 = , pop6 = 900,000 , region7 = , pop7 = 142,000 840,000 , region8 = , pop8 = 9,000 500,000 , region9 = , pop9 = 357,000 , region10 = , pop10 = 310,000 , region11 = , pop11 = 36,000 250,000 , region12 = , pop12 = 25,000 200,000 , region13 = , pop13 = 233,000 , region14 = , pop14 = 211,000 , region15 = , pop15 = 203,000 , region16 = , pop16 = 201,000 , region17 = , pop17 = 101,000 148,00 ...
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Coma
A coma is a deep state of prolonged unconsciousness in which a person cannot be awakened, fails to respond normally to painful stimuli, light, or sound, lacks a normal wake-sleep cycle and does not initiate voluntary actions. Coma patients exhibit a complete absence of wakefulness and are unable to consciously feel, speak or move. Comas can be derived by natural causes, or can be medically induced. Clinically, a coma can be defined as the inability consistently to follow a one-step command. It can also be defined as a score of ≤ 8 on the Glasgow Coma Scale (GCS) lasting ≥ 6 hours. For a patient to maintain consciousness, the components of ''wakefulness'' and ''awareness'' must be maintained. Wakefulness describes the quantitative degree of consciousness, whereas awareness relates to the qualitative aspects of the functions mediated by the cortex, including cognitive abilities such as attention, sensory perception, explicit memory, language, the execution of tasks, temporal ...
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People From Dessau-Roßlau
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of ...
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1854 Deaths
Events January–March * January 4 – The McDonald Islands are discovered by Captain William McDonald aboard the ''Samarang''. * January 6 – The fictional detective Sherlock Holmes is perhaps born. * January 9 – The Teutonia Männerchor in Pittsburgh, U.S.A. is founded to promote German culture. * January 20 – The North Carolina General Assembly in the United States charters the Atlantic and North Carolina Railroad, to run from Goldsboro through New Bern, to the newly created seaport of Morehead City, near Beaufort. * January 21 – The iron clipper runs aground off the east coast of Ireland, on her maiden voyage out of Liverpool, bound for Australia, with the loss of at least 300 out of 650 on board. * February 11 – Major streets are lit by coal gas for the first time by the San Francisco Gas Company; 86 such lamps are turned on this evening in San Francisco, California. * February 13 – Mexican troops force William W ...
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1799 Births
Events January–June * January 9 – British Prime Minister William Pitt the Younger introduces an income tax of two shillings to the pound, to raise funds for Great Britain's war effort in the French Revolutionary Wars. * January 17 – Maltese patriot Dun Mikiel Xerri, along with a number of other patriots, is executed. * January 21 – The Parthenopean Republic is established in Naples by French General Jean Étienne Championnet; King Ferdinand I of the Two Sicilies flees. * February 9 – Quasi-War: In the single-ship action of USS ''Constellation'' vs ''L'Insurgente'' in the Caribbean, the American ship is the victor. * February 28 – French Revolutionary Wars: Action of 28 February 1799 – British Royal Navy frigate HMS ''Sybille'' defeats the French frigate ''Forte'', off the mouth of the Hooghly River in the Bay of Bengal, but both captains are killed. * March 1 – Federalist James Ross becomes President pro tempore of the United States Sen ...
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Georg Hirsch
Georg may refer to: * ''Georg'' (film), 1997 *Georg (musical), Estonian musical * Georg (given name) * Georg (surname) * , a Kriegsmarine coastal tanker See also * George (other) George may refer to: People * George (given name) * George (surname) * George (singer), American-Canadian singer George Nozuka, known by the mononym George * George Washington, First President of the United States * George W. Bush, 43rd Preside ...
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Basedow’s Disease
Graves' disease (german: Morbus Basedow), also known as toxic diffuse goiter, is an autoimmune disease that affects the thyroid. It frequently results in and is the most common cause of hyperthyroidism. It also often results in an enlarged thyroid. Signs and symptoms of hyperthyroidism may include irritability, muscle weakness, sleeping problems, a fast heartbeat, poor tolerance of heat, diarrhea and unintentional weight loss. Other symptoms may include thickening of the skin on the shins, known as pretibial myxedema, and eye bulging, a condition caused by Graves' ophthalmopathy. About 25 to 30% of people with the condition develop eye problems. The exact cause of the disease is unclear; however, it is believed to involve a combination of genetic and environmental factors. A person is more likely to be affected if they have a family member with the disease. If one twin is affected, a 30% chance exists that the other twin will also have the disease. The onset of disease may be ...
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Exophthalmos
Exophthalmos (also called exophthalmus, exophthalmia, proptosis, or exorbitism) is a bulging of the eye anteriorly out of the orbit. Exophthalmos can be either bilateral (as is often seen in Graves' disease) or unilateral (as is often seen in an orbital tumor). Complete or partial dislocation from the orbit is also possible from trauma or swelling of surrounding tissue resulting from trauma. In the case of Graves' disease, the displacement of the eye results from abnormal connective tissue deposition in the orbit and extraocular muscles, which can be visualized by CT or MRI. If left untreated, exophthalmos can cause the eyelids to fail to close during sleep, leading to corneal dryness and damage. Another possible complication is a form of redness or irritation called superior limbic keratoconjunctivitis, in which the area above the cornea becomes inflamed as a result of increased friction when blinking. The process that is causing the displacement of the eye may also compre ...
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Goitre
A goitre, or goiter, is a swelling in the neck resulting from an enlarged thyroid gland. A goitre can be associated with a thyroid that is not functioning properly. Worldwide, over 90% of goitre cases are caused by iodine deficiency. The term is from the Latin ''gutturia'', meaning throat. Most goitres are not cancerous ( benign), though they may be potentially harmful. Signs and symptoms A goitre can present as a palpable or visible enlargement of the thyroid gland at the base of the neck. A goitre, if associated with hypothyroidism or hyperthyroidism, may be present with symptoms of the underlying disorder. For hyperthyroidism, the most common symptoms are associated with adrenergic stimulation: tachycardia (increased heart rate), palpitations, nervousness, tremor, increased blood pressure and heat intolerance. Clinical manifestations are often related to hypermetabolism, (increased metabolism), excessive thyroid hormone, an increase in oxygen consumption, metabolic changes in ...
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Tachycardia
Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate. In general, a resting heart rate over 100 beats per minute is accepted as tachycardia in adults. Heart rates above the resting rate may be normal (such as with exercise) or abnormal (such as with electrical problems within the heart). Complications Tachycardia can lead to fainting. When the rate of blood flow becomes too rapid, or fast blood flow passes on damaged endothelium, it increases the friction within vessels resulting in turbulence and other disturbances. According to the Virchow's triad, this is one of the three conditions that can lead to thrombosis (i.e., blood clots within vessels). Causes Some causes of tachycardia include: * Adrenergic storm * Anaemia * Anxiety * Atrial fibrillation * Atrial flutter * Atrial tachycardia * Atrioventricular reentrant tachycardia * AV nodal reentrant tachycardia * Brugada syndrome * Circulatory shock and its various causes ( ...
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Basedow’s Syndrome
Graves' disease (german: Morbus Basedow), also known as toxic diffuse goiter, is an autoimmune disease that affects the thyroid. It frequently results in and is the most common cause of hyperthyroidism. It also often results in an enlarged thyroid. Signs and symptoms of hyperthyroidism may include irritability, muscle weakness, sleeping problems, a fast heartbeat, poor tolerance of heat, diarrhea and unintentional weight loss. Other symptoms may include thickening of the skin on the shins, known as pretibial myxedema, and eye bulging, a condition caused by Graves' ophthalmopathy. About 25 to 30% of people with the condition develop eye problems. The exact cause of the disease is unclear; however, it is believed to involve a combination of genetic and environmental factors. A person is more likely to be affected if they have a family member with the disease. If one twin is affected, a 30% chance exists that the other twin will also have the disease. The onset of disease may be ...
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