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History Of Cancer
The history of cancer describes the development of the field of oncology and its role in the history of medicine. Early diagnosis The earliest known descriptions of cancer appear in several papyri from Ancient Egypt. The Edwin Smith Papyrus was written around 1600 BC (possibly a fragmentary copy of a text from 2500 BC) and contains a description of cancer, as well as a procedure to remove breast tumours by cauterization, wryly stating that the disease has no treatment. However, incidents of cancer were rare. In a study by the University of Manchester, only one case was found "in the investigation of hundreds of Egyptian mummies, with few references to cancer in literary evidence." Hippocrates ( – ) described several kinds of cancer, referring to them by the term ''καρκινος'' (''carcinos''), the Greek word for crab or crayfish, as well as ''carcinoma''. This comes from the appearance of the cut surface of a solid malignant tumour, with "the veins stretched on all sides ...
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Clara Jacobi-Tumor
Clara may refer to: Organizations * CLARA, Latin American academic computer network organization * Clara.Net, a European ISP * Consolidated Land and Rail Australia, a property development consortium People * Clara (given name), a feminine given name (includes a list of people and fictional characters with this name) * Saint Clara or Clare of Assisi ; Surname * Florian Clara (born 1988), Italian luger * Roland Clara (born 1982), Italian cross country skier Places France * Clara, Pyrénées-Orientales, a commune of the Pyrénées-Orientales ''département'' in southwestern France Ireland * Clara, County Kilkenny, a parish * Clara, County Offaly, a town in Ireland ** Clara Bog, a wetland near the town of Clara, County Offaly * Clara, County Wicklow, sometimes referred to as the "smallest village in Ireland" United Kingdom * Clara Vale, a village in Tyne and Wear, England United States * Clara, Florida, area on the border of Taylor County and Dixie County * Clara City, Minneso ...
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Lymph
Lymph (from Latin, , meaning "water") is the fluid that flows through the lymphatic system, a system composed of lymph vessels (channels) and intervening lymph nodes whose function, like the venous system, is to return fluid from the tissues to be recirculated. At the origin of the fluid-return process, interstitial fluid—the fluid between the cells in all body tissues—enters the lymph capillaries. This lymphatic fluid is then transported via progressively larger lymphatic vessels through lymph nodes, where substances are removed by tissue lymphocytes and circulating lymphocytes are added to the fluid, before emptying ultimately into the right or the left subclavian vein, where it mixes with central venous blood. Because it is derived from interstitial fluid, with which blood and surrounding cells continually exchange substances, lymph undergoes continual change in composition. It is generally similar to blood plasma, which is the fluid component of blood. Lymph return ...
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William Coley
William Bradley Coley (January 12, 1862 – April 16, 1936) was an American bone surgeon and cancer researcher best known for his early contributions to the study of cancer immunotherapy. Although his work was not proven effective in his lifetime, modern discoveries and research in immunology have led to a greater appreciation for his work in cancer immunotherapy and his targeted therapy, Coley's toxins. Today, Coley is recognized as the ''Father of Cancer Immunotherapy'' for his contributions to the science. Early life and career Education William Coley was born on January 12, 1862, in Saugatuck, a neighborhood of Westport, Connecticut. His parents were Horace Bradley Coley and Clarina B. Wakeman. He received his bachelor's degree in Classics from Yale University and his medical degree from Harvard Medical School in 1888. After his schooling, Coley began working at New York Hospital, now Weill Cornell Medical Center, as a surgical intern. Early sarcoma patients In 1890, Coley b ...
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Cancer Survivor
A cancer survivor is a person with cancer of any type who is still living. Whether a person becomes a survivor at the time of diagnosis or after completing treatment, whether people who are actively dying are considered survivors, and whether healthy friends and family members of the cancer patient are also considered survivors, varies from group to group. Some people who have been diagnosed with cancer reject the term ''survivor'' or disagree with some definitions of it. How many people are cancer survivors depends on the definition used. Nearly 65% of adults diagnosed with cancer in the developed world are expected to live at least five years after the cancer is discovered. In the U.S. for example, about 11 million Americans alive today—one in 30 people–are either currently undergoing treatment for cancer or have done so in the past. Many cancer survivors describe the process of living with and beating cancer as a life-changing experience. It is not uncommon for survivo ...
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Asepsis
Asepsis is the state of being free from disease-causing micro-organisms (such as pathogenic bacteria, viruses, pathogenic fungi, and parasites). There are two categories of asepsis: medical and surgical. The modern day notion of asepsis is derived from the older antiseptic techniques, a shift initiated by different individuals in the 19th century who introduced practices such as the sterilizing of surgical tools and the wearing of surgical gloves during operations. The goal of asepsis is to eliminate infection, not to achieve sterility. Ideally, a surgical field is sterile, meaning it is free of all biological contaminants (e.g. fungi, bacteria, viruses), not just those that can cause disease, putrefaction, or fermentation. Even in an aseptic state, a condition of sterile inflammation may develop. The term often refers to those practices used to promote or induce asepsis in an operative field of surgery or medicine to prevent infection. History The modern concept of asepsis evol ...
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Alexander Monro (primus)
Alexander Monro (19 September 169710 July 1767) was a Scottish surgeon and anatomist. His father, the surgeon John Monro, had been a prime mover in the foundation of the Edinburgh Medical School and had arranged Alexander's education in the hope that his son might become the first Professor of Anatomy in the new university medical school. After medical studies in Edinburgh, London, Paris and Leiden, Alexander Monro returned to Edinburgh, and pursued a career as a surgeon and anatomy teacher. With the support of his father and the patronage of the Edinburgh Lord Provost George Drummond, Alexander Monro was appointed foundation Professor of Anatomy at the University of Edinburgh. His lectures, delivered in English, rather than the conventional Latin, proved popular with students and his qualities as a teacher contributed to the success and reputation of the Edinburgh medical school. He is known as Alexander Monro Primus or Senior to distinguish him from his son Alexander Monro ...
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Surgery
Surgery ''cheirourgikē'' (composed of χείρ, "hand", and ἔργον, "work"), via la, chirurgiae, meaning "hand work". is a medical specialty that uses operative manual and instrumental techniques on a person to investigate or treat a pathological condition such as a disease or injury, to help improve bodily function, appearance, or to repair unwanted ruptured areas. The act of performing surgery may be called a surgical procedure, operation, or simply "surgery". In this context, the verb "operate" means to perform surgery. The adjective surgical means pertaining to surgery; e.g. surgical instruments or surgical nurse. The person or subject on which the surgery is performed can be a person or an animal. A surgeon is a person who practices surgery and a surgeon's assistant is a person who practices surgical assistance. A surgical team is made up of the surgeon, the surgeon's assistant, an anaesthetist, a circulating nurse and a surgical technologist. Surgery usually ...
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Campbell De Morgan
Campbell Greig De Morgan (22 November 1811 – 12 April 1876) was a British surgeon who first speculated that cancer arose locally and then spread, first to the lymph nodes and then more widely in the body. His name is used to describe the non cancerous Campbell de Morgan spot; bright red spots that may appear on the skin in later life and which he was the first to note in medical literature. Life He was born in 1811 at Clovelly near Bideford, Devon, England in 1811, youngest of three sons of Colonel John de Morgan (1772-1816), of the Indian Army, and Elizabeth (1776-1856), daughter of John Dodson and granddaughter of the mathematician James Dodson. The de Morgan family, of Huguenot origin, had a long association with the British East India Company. The mathematician Augustus De Morgan was an older brother. He trained at University College Hospital, London and went on to be a house surgeon at the Middlesex Hospital where he remained for the rest of his career. He was activel ...
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Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. The newly pathological sites, then, are metastases (mets). It is generally distinguished from cancer invasion, which is the direct extension and penetration by cancer cells into neighboring tissues. Cancer occurs after cells are genetically altered to proliferate rapidly and indefinitely. This uncontrolled proliferation by mitosis produces a primary heterogeneic tumour. The cells which constitute the tumor eventually undergo metaplasia, followed by dysplasia then anaplasia, resulting in a malignant phenotype. This malignancy allows for invasion into the circulation, followed by invasion to a second site for tumorigenesis. Some cancer cells known as circulating tumor cells acquire the ability to penetrate the walls of lymphatic or blood vessels, after which they are ...
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Chimney Sweep
A chimney sweep is a person who clears soot and creosote from chimneys. The chimney uses the pressure difference caused by a hot column of gas to create a draught and draw air over the hot coals or wood enabling continued combustion. Chimneys may be straight or contain many changes of direction. During normal operation, a layer of creosote builds up on the inside of the chimney, restricting the flow. The creosote can also catch fire, setting the chimney (and potentially the entire building) alight. The chimney must be swept to remove the soot. In Great Britain, master sweeps took apprentices, typically workhouse or orphan boys, and trained them to climb chimneys. In the German States, master sweeps belonged to trade guilds and did not use climbing boys. In Italy, Belgium, and France climbing boys were used. The occupation requires some dexterity, and carries health risks. History The Tudors in England had established the risk of chimneys and an ordnance was created in 15 ...
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Scrotum
The scrotum or scrotal sac is an anatomical male reproductive structure located at the base of the penis that consists of a suspended dual-chambered sac of skin and smooth muscle. It is present in most terrestrial male mammals. The scrotum contains the external spermatic fascia, testes, epididymis, and ductus deferens. It is a distention of the perineum and carries some abdominal tissues into its cavity including the testicular artery, testicular vein, and pampiniform plexus. The perineal raphe is a small, vertical, slightly raised ridge of scrotal skin under which is found the scrotal septum. It appears as a thin longitudinal line that runs front to back over the entire scrotum. In humans and some other mammals the scrotum becomes covered with pubic hair at puberty. The scrotum will usually tighten during penile erection and when exposed to cold temperatures. One testis is typically lower than the other to avoid compression in the event of an impact. The scrotum is biolo ...
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Percivall Pott
Percivall Pott (6 January 1714, in London – 22 December 1788) was an English surgeon, one of the founders of orthopaedics, and the first scientist to demonstrate that a cancer may be caused by an environmental carcinogen. Career He was the son of Percivall Pott senior. His father died when he was a child, but Joseph Wilcocks, Bishop of Rochester, who was a relative of his mother, paid for his education. He served his apprenticeship with Edward Nourse, assistant surgeon to St Bartholomew's Hospital, and in 1736 was admitted to the Barbers' Company and licensed to practice. He became assistant surgeon to St Bartholomew's in 1744 and full surgeon from 1749 till 1787. As the first surgeon of his day in England, excelling even his pupil, John Hunter, on the practical side, Pott introduced various important innovations in procedure, doing much to abolish the extensive use of escharotics and the cautery that was prevalent when he began his career. In 1756, Pott sustained a bro ...
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