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Heterosubtypic Immunity
"Heterosubtypic immunity (HSI) is defined as cross-protection to infection with an influenza A virus serotype other than the one used for primary infection." In layman's terms: an 'infection with "seasonal" influenza A viruses could induce immunity against unrelated sub-strains.'Leicester Mercury The ''Leicester Mercury'' is a British regional newspaper for the city of Leicester and the neighbouring counties of Leicestershire and Rutland. The paper began in the 19th century as the ''Leicester Daily Mercury'' and later changed to its pre ... ''Winter flu could help protect kids'', 30 October 2009 References {{DEFAULTSORT:Influenza A Virus Immunology Influenza vaccines Influenza A virus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Influenza A Virus
''Influenza A virus'' (''Alphainfluenzavirus influenzae'') or IAV is the only species of the genus ''Alphainfluenzavirus'' of the virus family '' Orthomyxoviridae''. It is a pathogen with strains that infect birds and some mammals, as well as causing seasonal flu in humans. Mammals in which different strains of IAV circulate with sustained transmission are bats, pigs, horses and dogs; other mammals can occasionally become infected. IAV is an enveloped negative-sense RNA virus, with a segmented genome. Through a combination of mutation and genetic reassortment the virus can evolve to acquire new characteristics, enabling it to evade host immunity and occasionally to jump from one species of host to another. Subtypes of IAV are defined by the combination of the antigenic H and N proteins in the viral envelope; for example, "H1N1" designates an IAV subtype that has a type-1 hemagglutinin (H) protein and a type-1 neuraminidase (N) protein. Almost all possible combinations of H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serotype
A serotype or serovar is a distinct variation within a species of bacteria or virus or among immune cells of different individuals. These microorganisms, viruses, or Cell (biology), cells are classified together based on their shared reactivity between their surface antigens and a particular antiserum, allowing the classification of organisms to a Infraspecific name, level below the species. A group of serovars with common antigens is called a serogroup or sometimes ''serocomplex''. Serotyping often plays an essential role in determining species and subspecies. The ''Salmonella'' genus of bacteria, for example, has been determined to have over 2600 serotypes. ''Vibrio cholerae'', the species of bacteria that causes cholera, has over 200 serotypes, based on cell antigens. Only two of them have been observed to produce the potent enterotoxin that results in cholera: O1 and O139. Serotypes were discovered in hemolytic streptococci by the American microbiologist Rebecca Lancefield i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Primary Infection
infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune systems. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Treatment for infections depends on the type of pathogen involved. Common medications include: * Antibiotics for bacterial infections. * Antivirals for viral infections. * Antifungals for fungal infections. * Antiprotozoals for protozoan infections. * Antihelminthics for infections caused by parasitic worms. Infectious diseases remain a significant global health concern, causing approximately 9.2 million deaths in 20 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Virology
The ''Journal of Virology'' is a biweekly peer-reviewed scientific journal that covers research concerning all aspects of virology. It was established in 1967 and is published by the American Society for Microbiology. Research papers are available free online 6 months after print publication. The current editors-in-chief are Felicia Goodrum (University of Arizona) and Stacey Schultz-Cherry ( St. Jude Children's Research Hospital). Past editors-in-chief include Rozanne M. Sandri-Goldin (University of California, Irvine, California) (2012-2022), Lynn W. Enquist (2002–2012), Thomas Shenk (1994–2002), and Arnold J. Levine (1984–1994).American Society for Microbiology: ASM Announces Appointments of New Editors In Chief for CMR and JVI [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Layman's Terms
Plain English (also referred to as layman's terms) is a mode of writing or speaking the English language intended to be easy to understand regardless of one's familiarity with a given topic. It usually avoids the use of rare words and uncommon euphemisms to explain the subject. Plain English wording is intended to be suitable for almost anyone, and it allows for good understanding to help readers know a topic. It is considered a part of plain language. Etymology The term derives from the 16th-century idiom "in plain English", meaning "in clear, straightforward language" as well as the Latin ''planus'' ("flat"). Another name for the term, layman's terms, is derived from the idiom " in layman's terms" which refers to language phrased simply enough that a layman, or common person without expertise on the subject, can understand. History United Kingdom In 1946, writer George Orwell wrote an essay titled, "Politics and the English Language", where he criticized the dangers of "ugly and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunity (medical)
In biology, immunity is the state of being insusceptible or resistant to a noxious agent or process, especially a pathogen or infectious disease. Immunity may occur naturally or be produced by prior exposure or immunization. Innate and adaptive The immune system has Innate immune system, innate and Adaptive immune system, adaptive components. Innate immunity is present in all metazoans, immune responses: inflammation, inflammatory responses and phagocytosis. The adaptive component, on the other hand, involves more advanced lymphocyte, lymphatic cells that can distinguish between specific "non-self" substances in the presence of "self". The reaction to foreign substances is etymologically described as inflammation while the non-reaction to self substances is described as immunity. The two components of the immune system create a dynamic biological environment where "health" can be seen as a physical state where the self is immunologically spared, and what is foreign is inflammat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leicester Mercury
The ''Leicester Mercury'' is a British regional newspaper for the city of Leicester and the neighbouring counties of Leicestershire and Rutland. The paper began in the 19th century as the ''Leicester Daily Mercury'' and later changed to its present title. Early history The paper was founded by James Thompson, already proprietor of the ''Leicester Chronicle'' which he had merged with the ''Leicestershire Mercury'' ten years earlier. The ''Leicester Daily Mercury'' was an evening paper, the first to be published in Leicester, and provided support to the Liberal Party in the general election. The first issue was published on 31 January 1874 from the paper's offices at 3 St Martin's, consisting of four pages of five columns each. The paper had a staff of 25 and a circulation of 5,000. Recent history The ''Leicester Mercury'' has experienced declining circulation, similar to other regional British newspapers. The paper had an average circulation of 69,069 per day in the first half ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunology
Immunology is a branch of biology and medicine that covers the study of Immune system, immune systems in all Organism, organisms. Immunology charts, measures, and contextualizes the Physiology, physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders (such as Autoimmune disease, autoimmune diseases, Hypersensitivity, hypersensitivities, immune deficiency, and transplant rejection); and the physical, chemical, and physiological characteristics of the components of the immune system ''in vitro'', ''In situ#Biology and biomedical engineering, in situ'', and ''in vivo''. Immunology has applications in numerous disciplines of medicine, particularly in the fields of organ transplantation, oncology, rheumatology, virology, bacteriology, parasitology, psychiatry, and dermatology. The term was coined by Russian biologist Ilya Ilyich Mechnikov, who advanced studies on immunology and received the Nob ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Influenza Vaccines
Influenza vaccines, colloquially known as flu shots or the flu jab, are vaccines that protect against infection by influenza viruses. New versions of the vaccines are developed twice a year, as the influenza virus rapidly changes. While their effectiveness varies from year to year, most provide modest to high protection against influenza. Vaccination against influenza began in the 1930s, with large-scale availability in the United States beginning in 1945. Both the World Health Organization and the US Centers for Disease Control and Prevention (CDC) recommend yearly vaccination for nearly all people over the age of six months, especially those at high risk, and the influenza vaccine is on the World Health Organization's List of Essential Medicines. The European Centre for Disease Prevention and Control (ECDC) also recommends yearly vaccination of high-risk groups, particularly pregnant women, the elderly, children between six months and five years, and those with certain hea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
