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Gentiana Olivieri
''Gentiana olivieri'' (Chinese: xie wan que qin jiao) is a species of flowering plant in the family ''Gentianaceae Gentianaceae is a family of flowering plants of 105 genera and about 1600 species. Etymology The family takes its name from the genus ''Gentiana'', named after the Illyrian king Gentius. Distribution Distribution is cosmopolitan (species), cosm ...'' found in Asia. Bioassay-directed fractionation techniques led to isolation of isoorientin as the main hypoglycemic component in ''G. olivieri''.Hypoglycaemic activity of Gentiana olivieri and isolation of the active constituent through bioassay- directed fractionation techniques. Ekrem Sezik, Mustafa Aslan, Erdem Yesilada, Shigeru Ito, Life Sciences, 28 January 2005, Volume 76, Issue 11, Pages 1223–1238, References olivieri Flora of China Plants described in 1838 Taxa named by August Grisebach {{Gentianales-stub ...
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August Grisebach
August Heinrich Rudolf Grisebach (; 17 April 18149 May 1879) was a German botanist and phytogeographer. Biography Grisebach studied at the Lyceum in Hanover, the cloister-school at Ilfeld, and the University of Göttingen. He graduated in medicine from the University of Berlin in 1836. He undertook expeditions to Provence, Turkey, the Balkans, and Norway. In 1837 he became associate professor and in 1847 full professor at the medical faculty in Göttingen and was named director of the botanical garden there in 1875. While his main fields of interest were phytogeography and systematics, especially the Gentianaceae and Malpighiaceae, he considered his ''Flora of the British West Indian Islands'' his most important work. Much of his collection, especially the types of species described by him, are housed at the Göttingen University Herbarium. His taxonomic classification is set out in his ''Grundriss der systematischen Botanik'' (1854). His son Eduard was an author, lawyer a ...
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Flowering Plant
Flowering plants are plants that bear flowers and fruits, and form the clade Angiospermae (). The term angiosperm is derived from the Ancient Greek, Greek words (; 'container, vessel') and (; 'seed'), meaning that the seeds are enclosed within a fruit. The group was formerly called Magnoliophyta. Angiosperms are by far the most diverse group of Embryophyte, land plants with 64 Order (biology), orders, 416 Family (biology), families, approximately 13,000 known Genus, genera and 300,000 known species. They include all forbs (flowering plants without a woody Plant stem, stem), grasses and grass-like plants, a vast majority of broad-leaved trees, shrubs and vines, and most aquatic plants. Angiosperms are distinguished from the other major seed plant clade, the gymnosperms, by having flowers, xylem consisting of vessel elements instead of tracheids, endosperm within their seeds, and fruits that completely envelop the seeds. The ancestors of flowering plants diverged from the commo ...
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Gentianaceae
Gentianaceae is a family of flowering plants of 105 genera and about 1600 species. Etymology The family takes its name from the genus ''Gentiana'', named after the Illyrian king Gentius. Distribution Distribution is cosmopolitan (species), cosmopolitan. Characteristics The family consists of trees, shrubs and herbs showing a wide range of colours and floral patterns. Flowers are actinomorphic and bisexual with fused sepals and petals. The stamens are attached to the inside of the petals (Stamens#Sexual reproduction in plants, epipetalous) and alternate with the corolla lobes. There is a glandular disk at the base of the gynoecium, and flowers have parietal placentation. The inflorescence is cymose, with simple or complex Cyme (botany), cymes. The fruits are dehiscent septicidal capsules splitting into two halves, rarely some species have a berry (botany), berry. Seeds are small with copiously oily endosperms and a straight embryo. The habit varies from small trees, pachycaul sh ...
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Bioassay-directed Fractionation
Fractionation is a separation process in which a certain quantity of a mixture (of gasses, solids, liquids, enzymes, or isotopes, or a suspension) is divided during a phase transition, into a number of smaller quantities (fractions) in which the composition varies according to a gradient. Fractions are collected based on differences in a specific property of the individual components. A common trait in fractionations is the need to find an optimum between the amount of fractions collected and the desired purity in each fraction. Fractionation makes it possible to isolate more than two components in a mixture in a single run. This property sets it apart from other separation techniques. Fractionation is widely employed in many branches of science and technology. Mixtures of liquids and gasses are separated by fractional distillation by difference in boiling point. Fractionation of components also takes place in column chromatography by a difference in affinity between stationar ...
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Isoorientin
Isoorientin (homoorientin) is a flavone, a chemical flavonoid-like compound. It is the luteolin-6-''C''-glucoside. Natural occurrence Isoorientin can be isolated from the passion flower, '' Vitex negundo'', '' Terminalia myriocarpa'', the Açaí palm, and ''Swertia japonica''. Potential pharmacology Isoorientin has been studied for its potential pharmacological activity. Bioassay-directed fractionation techniques led to isolation of isoorientin as the main hypoglycaemic component in ''Gentiana olivieri''. Studies also showed that isoorientin is a potential neuroprotective compound against Alzheimer's disease. Metabolism * Isoorientin 3'-O-methyltransferase See also * Orientin, the 8-C glucoside A glucoside is a glycoside that is chemically derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes. Th ... of luteolin. Referenc ...
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Hypoglycemic Agent
Drugs used in diabetes treat types of diabetes mellitus by decreasing glucose levels in the blood. With the exception of insulin, most GLP-1 receptor agonists ( liraglutide, exenatide, and others), and pramlintide, all diabetes medications are administered orally and are thus called oral hypoglycemic agents or oral antihyperglycemic agents. There are different classes of hypoglycemic drugs, and selection of the appropriate agent depends on the nature of diabetes, age, and situation of the person, as well as other patient factors. Type 1 diabetes or Diabetes mellitus is an endocrine disorder characterized by hyperglycemia due to autoimmune destruction of insulin-secreting pancreatic beta cells or from variable degrees of insulin resistance and deficiency. Chronic hyperglycemia of diabetes can lead to multiorgan damage, resulting in renal, neurologic, cardiovascular, and other serious complications. The treatment for Type 1 diabetes is insulin injection. Type 2 diabetes is t ...
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Gentiana
''Gentiana'' () is a genus of flowering plants belonging to the gentian family (Gentianaceae), the tribe Gentianeae, and the monophyletic subtribe Gentianinae. With over 300 species, it is considered a large genus. Gentians are notable for their mostly large trumpet-shaped flowers, which are often of an intense blue hue. The genus name is a tribute to Gentius, an Illyrian king who may have discovered tonic properties in gentians. Habitat This is a cosmopolitan genus, occurring in alpine habitats in temperate regions of Asia, Europe and the Americas. Some species also occur in northwestern Africa, eastern Australia, and New Zealand. They are annual, biennial, and perennial plants. Some are evergreen, others are not. Many gentians are difficult to grow outside their wild habitat, but several species are available in cultivation. Gentians are fully hardy and can grow in full sun or partial shade. They grow in well-drained, neutral-to-acid soils rich in humus. They are popular ...
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Flora Of China
The flora of China consists of a diverse range of plant species including over 39,000 vascular plants, 27,000 species of fungi and 3000 species of bryophytes.Wu, Z. Y., P. H. Raven & D. Y. Hong, eds. 2006. Flora of China. Vol. 22 (Poaceae). Science Press, Beijing, and Missouri Botanical Garden Press, St. Louis - http://www.efloras.org/volume_page.aspx?volume_id=2022&flora_id=2 More than 30,000 plant species are native to China, representing nearly one-eighth of the world's total plant species, including thousands found nowhere else on Earth. China's land, extending over 9.6 million km, contains a variety of ecosystems and climates for plants to grow in. Some of the main climates include shores, tropical and subtropical forests, deserts, elevated plateaus and mountains. The events of the continental drift and early Paleozoic Caledonian movement also play a part in creating climatic and geographical diversity resulting in high levels of endemic vascular flora. These landscapes prov ...
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Plants Described In 1838
Plants are the eukaryotes that form the kingdom Plantae; they are predominantly photosynthetic. This means that they obtain their energy from sunlight, using chloroplasts derived from endosymbiosis with cyanobacteria to produce sugars from carbon dioxide and water, using the green pigment chlorophyll. Exceptions are parasitic plants that have lost the genes for chlorophyll and photosynthesis, and obtain their energy from other plants or fungi. Most plants are multicellular, except for some green algae. Historically, as in Aristotle's biology, the plant kingdom encompassed all living things that were not animals, and included algae and fungi. Definitions have narrowed since then; current definitions exclude fungi and some of the algae. By the definition used in this article, plants form the clade Viridiplantae (green plants), which consists of the green algae and the embryophytes or land plants ( hornworts, liverworts, mosses, lycophytes, ferns, conifers and other gymn ...
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