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Epizootic Hemorrhagic Disease Virus
''Epizootic hemorrhagic disease virus'', often abbreviated to EHDV, is a species of the genus ''Orbivirus'', a member of the family ''Reoviridae''. It is the causative agent of epizootic hemorrhagic disease, an acute, infectious, and often fatal disease of wild ruminants. In North America, the most severely affected ruminant is the white-tailed deer (''Odocoileus virginianus''), although it may also infect mule deer, black-tailed deer, elk, bighorn sheep, and pronghorn antelope. It is often mistakenly referred to as “bluetongue virus” (BTV), another ''Orbivirus'' that like EHDV causes the host to develop a characteristic blue tongue due to systemic hemorrhaging and lack of oxygen in the blood. Despite showing clinical similarities, these two viruses are genetically distinct. Worldwide, eight serotypes of EHDV have been identified. Historically, only serotypes EHDV-1 and EHDV-2 have been found in North America, but recent research has discovered at least one more in the Midwe ...
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Orbivirus
''Orbivirus'' is a genus of double-stranded RNA viruses in the family ''Reoviridae'' and subfamily '' Sedoreovirinae''. Unlike other reoviruses, orbiviruses are arboviruses. They can infect and replicate within a wide range of arthropod and vertebrate hosts. Orbiviruses are named after their characteristic doughnut-shaped capsomers (''orbis'' in Latin means ring). Many orbiviruses are transmitted by ticks or haematophagus insect vectors (''Culicoides'', mosquitoes and sand flies) and have a wide host range that includes cattle, goats and sheep, wild ruminants, equids, camelids, marsupials, sloths, bats, birds, large canine and feline carnivores, and humans. The three economically most important orbiviruses are ''Bluetongue virus'', '' African horse sickness virus'', and '' Epizootic hemorrhagic disease virus'', all of which are transmitted by ''Culicoides'' species. The genus contains 22 species and at least 130 different serotypes. History In 1719, African horse sickne ...
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Reoviridae
''Reoviridae'' is a family of double-stranded RNA viruses. Member viruses have a wide host range, including vertebrates, invertebrates, plants, protists and fungi. They lack lipid envelopes and package their segmented genome within multi-layered capsids. Lack of a lipid envelope has allowed three-dimensional structures of these large complex viruses (diameter ∼60–100 nm) to be obtained, revealing a structural and likely evolutionary relationship to the cystovirus family of bacteriophage. There are currently 97 species in this family, divided among 15 genera in two subfamilies. Reoviruses can affect the gastrointestinal system (such as rotaviruses) and respiratory tract. The name "reo-" is an acronym for "''r''espiratory ''e''nteric ''o''rphan" viruses''.'' The term " orphan virus" refers to the fact that some of these viruses have been observed not associated with any known disease. Even though viruses in the family ''Reoviridae'' have more recently been identified with ...
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Epizootic Hemorrhagic Disease
Epizootic hemorrhagic disease (EHD) is a hemorrhagic disease of white-tailed deer (''Odocoileus virginianus'') caused by an infection of a virus from the genus ''Orbivirus'' subsequently called ''Epizootic hemorrhagic disease virus'' (EHDV). It is an infectious, and sometimes fatal, virus that is characterized by extensive hemorrhages, and is found throughout the United States. Large-scale outbreaks in wild ruminants affect livestock and the production industry. EHD has been found in some domestic ruminants and many species of deer including white-tailed deer, mule deer, elk, and pronghorn antelope.Center for Food Security and Public Health. 2006. Diseases Caused by the Epizootic Hemorrhagic Disease Virus Serogroup. Institute for International Cooperation in Animal Biologics. http://www.cfsph.iastate.edu/Factsheets/pdfs/epizootic_hemorrhagic_disease.pdf Seropositive black-tailed deer, fallow deer, red deer, wapiti, and roe deer have also been found, which essentially means that the ...
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White-tailed Deer
The white-tailed deer (''Odocoileus virginianus''), also known as the whitetail or Virginia deer, is a medium-sized deer native to North America, Central America, and South America as far south as Peru and Bolivia. It has also been introduced to New Zealand, all the Greater Antilles in the Caribbean (Cuba, Jamaica, Hispaniola, and Puerto Rico), and some countries in Europe, such as the Czech Republic, Finland, France, Germany, Romania and Serbia. In the Americas, it is the most widely distributed wild ungulate. In North America, the species is widely distributed east of the Rocky Mountains as well as in southwestern Arizona and most of Mexico, except Lower California. It is mostly displaced by the black-tailed or mule deer (''Odocoileus hemionus'') from that point west except for mixed deciduous riparian corridors, river valley bottomlands, and lower foothills of the northern Rocky Mountain region from Wyoming west to eastern Washington and eastern Oregon and north to nort ...
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Mule Deer
The mule deer (''Odocoileus hemionus'') is a deer indigenous to western North America; it is named for its ears, which are large like those of the mule. Two subspecies of mule deer are grouped into the black-tailed deer. Unlike the related white-tailed deer (''Odocoileus virginianus''), which is found throughout most of North America east of the Rocky Mountains and in the valleys of the Rocky Mountains from Idaho and Wyoming northward, mule deer are only found on the western Great Plains, in the Rocky Mountains, in the southwest United States, and on the west coast of North America. Mule deer have also been introduced to Argentina and Kauai, Hawaii. Taxonomy Mule deer can be divided into two main groups: the mule deer (''sensu stricto'') and the black-tailed deer. The first group includes all subspecies, except ''O. h. columbianus'' and '' O. h. sitkensis'', which are in the black-tailed deer group. The two main groups have been treated as separate species, but they hybridiz ...
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Black-tailed Deer
Two forms of black-tailed deer or blacktail deer that occupy coastal woodlands in the Pacific Northwest of North America are subspecies of the mule deer (''Odocoileus hemionus''). They have sometimes been treated as a species, but virtually all recent authorities maintain they are subspecies.Novak, R. M. (1999). ''Walker's Mammals of the World.'' 6th edition. Heffelfinger, J. (version 2 March 2011). Tails with a dark side: The truth about whitetail – mule deer hybrids.''Reid, F. A. (2006). ''Mammals of North America.'' 4th edition. Geist, V. (1998). ''Deer of the world: their evolution, behaviour, and ecology.'' Feldhamer, G. A., B. C. Thompson, and J. A. Chapman, editors (2003). Wild mammals of North America: biology, management, and conservation'' 2nd edition. The Columbian black-tailed deer (''Odocoileus hemionus columbianus'') is found in western North America, from Northern California into the Pacific Northwest of the United States and coastal British Columbia in Canada.B ...
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Bighorn Sheep
The bighorn sheep (''Ovis canadensis'') is a species of sheep native to North America. It is named for its large horns. A pair of horns might weigh up to ; the sheep typically weigh up to . Recent genetic testing indicates three distinct subspecies of ''Ovis canadensis'', one of which is endangered: ''O. c. sierrae''. Sheep originally crossed to North America over the Bering Land Bridge from Siberia; the population in North America peaked in the millions, and the bighorn sheep entered into the mythology of Native Americans. By 1900, the population had crashed to several thousand, due to diseases introduced through European livestock and overhunting. Taxonomy and genetics ''Ovis canadensis'' is one of two species of mountain sheep in North America; the other species being ''O. dalli'', the Dall sheep. Wild sheep crossed the Bering land bridge from Siberia into Alaska during the Pleistocene (about 750,000 years ago) and subsequently spread through western North America as far s ...
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Pronghorn
The pronghorn (, ) (''Antilocapra americana'') is a species of artiodactyl (even-toed, hoofed) mammal indigenous to interior western and central North America. Though not an antelope, it is known colloquially in North America as the American antelope, prong buck, pronghorn antelope and prairie antelope, because it closely resembles the antelopes of the Old World and fills a similar ecological niche due to parallel evolution. It is the only surviving member of the family Antilocapridae. During the Pleistocene epoch, about 11 other antilocaprid species existed in North America.Smithsonian Institution. North American MammalsPronghorn ''Antilocapra americana''/ref> Three other genera (''Capromeryx'', ''Stockoceros'' and ''Tetrameryx'') existed when humans entered North America but are now extinct. As a member of the superfamily Giraffoidea, the pronghorn's closest living relatives are the giraffe and okapi. See Fig. S10 in Supplementary Information. The Giraffoidea are in ...
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Culicoides Variipennis
''Culicoides variipennis'' is a long biting midge. It is a part of the subgenus ''Monoculicoides'' and has many subspecies. Found in North America, ''C. variipennis'' transmits Bluetongue virus, African horse sickness virus, akabane virus, and epizootic hemorrhagic disease. Anatomy The ''C. variipennis'' is less than long, which makes it difficult to keep from livestock. The wings of ''C. variipennis'' are spotted and narrow with few veins; the wings fold over the abdomen while the ''C. variipennis'' is at rest. The max flight range for male ''C. variipennis'' is and for females , while the mean flight range is . Flight activity is dependent on the light intensity and temperature; most flight, and thus most bites, occur around dawn and dusk. A distinction between male and female ''C. variipennis'' is that females have different mouthparts that allow them to blood feed. Life cycle The life cycle of the ''C. variipennis'' is from half a year to three years. The larva, found ty ...
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Rotavirus
''Rotavirus'' is a genus of double-stranded RNA viruses in the family ''Reoviridae''. Rotaviruses are the most common cause of diarrhoeal disease among infants and young children. Nearly every child in the world is infected with a rotavirus at least once by the age of five. Immunity develops with each infection, so subsequent infections are less severe. Adults are rarely affected. There are nine species of the genus, referred to as A, B, C, D, F, G, H, I and J. ''Rotavirus A'', the most common species, causes more than 90% of rotavirus infections in humans. The virus is transmitted by the faecal-oral route. It infects and damages the cells that line the small intestine and causes gastroenteritis (which is often called "stomach flu" despite having no relation to influenza). Although rotavirus was discovered in 1973 by Ruth Bishop and her colleagues by electron micrograph images and accounts for approximately one third of hospitalisations for severe diarrhoea in infants an ...
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Coltivirus
Coltivirus is a genus of viruses (belonging to the ''Reoviridae'' family) that infects vertebrates and invertebrates. It includes the causative agent of Colorado tick fever. Colorado tick fever virus can cause a fever, chills, headache, photophobia, myalgia, arthralgia, and lethargy. Children, in particular, may develop a hemorrhagic disease. Leukopenia with both lymphocytes and neutrophils is very common for Colorado tick fever virus. In either case, the infection can lead to encephalitis or meningitis. Virology ''Coltivirus'' is a genus of viruses. Viruses are intracellular parasites that do not have the necessary means to reproduce on their own, so they have instead to hijack the machinery of a host cell. Only then can they synthesize their viral proteins and create progeny. There are two types of viruses, distinguished by their type of genetic material. DNA viruses have genomes consisting of deoxyribonucleic acid (or DNA), while RNA viruses, like ''Coltivirus'', have an R ...
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Equine Encephalosis Virus
''Equine encephalosis virus'' (''EEV'') is a species of virus the ''Orbivirus'' genus, and a member of the ''Reoviridae'' family, related to '' African horse sickness virus'' (AHSV) and ''Bluetongue virus'' (BTV). First described in South Africa over a hundred years ago by Arnold Theiler, EEV is the causative agent of equine encephalosis (EE), an arthropod-borne disease transmitted by the ''Culicoides spp.'' midges affecting all equids. Since then the disease has become both widespread and prevalent, taking on epidemic proportions in certain parts of the country. Serological studies estimated a presence of anti-EEV antibodies in over 75% of all South African horses. Prior to 2008, ''Equine encephalosis virus'' had been identified and isolated only in South Africa, where seven antigenetically distinct serotypes, EEV1-7, have been characterised. In 2009, the outbreak of a febrile horse disease across Israel, later diagnosed as EEV, caused great concern primarily due to the s ...
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