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Endoscopic Optical Coherence Tomography Imaging
Endoscopic optical coherence tomography, also intravascular optical coherence tomography is a catheter-based imaging application of optical coherence tomography (OCT). It is capable of acquiring high-resolution images from inside a blood vessel using optical fibers and laser technology. One of its main applications is for coronary arteries, which are often treated by endoscopic, minimally invasive surgical procedures. Other applications for peripheral arteries and for neurovascular procedures have been proposed and are being investigated. Neurovascular applications required significant technological developments, due to the highly tortuous anatomy of the cerebrovasculature. Intravascular OCT rapidly creates three-dimensional images at a resolution of approximately 15 micrometers, an improved resolution with respect to intravascular ultrasound and coronary angiogram, the other imaging techniques. This offers additional information that can be used to optimize the treatment an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atherosclerotic Plaque
An atheroma, or atheromatous plaque, is an abnormal accumulation of material in the inner layer of an arterial wall. The material consists of mostly macrophage cells, or debris, containing lipids, calcium and a variable amount of fibrous connective tissue. The accumulated material forms a swelling in the artery wall, which may intrude into the lumen of the artery, narrowing it and restricting blood flow. Atheroma is the pathological basis for the disease entity atherosclerosis, a subtype of arteriosclerosis. Signs and symptoms For most people, the first symptoms result from atheroma progression within the heart arteries, most commonly resulting in a heart attack and ensuing debility. The heart arteries are difficult to track because they are small (from about 5 mm down to microscopic), they are hidden deep within the chest and they never stop moving. Additionally, all mass-applied clinical strategies focus on both minimal cost and the overall safety of the procedure. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Interferometry
Interferometry is a technique which uses the ''interference (wave propagation), interference'' of Superposition principle, superimposed waves to extract information. Interferometry typically uses electromagnetic waves and is an important investigative technique in the fields of astronomy, Optical fiber, fiber optics, engineering metrology, optical metrology, oceanography, seismology, spectroscopy (and its applications to chemistry), quantum mechanics, Nuclear physics, nuclear and particle physics, plasma physics, interactome, biomolecular interactions, surface profiling, microfluidics, mechanical stress/strain measurement, velocimetry, optometry, and making holograms. Interferometers are devices that extract information from interference. They are widely used in science and industry for the measurement of microscopic displacements, refractive index changes and surface irregularities. In the case with most interferometers, light from a single source is split into two beams that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vascular Procedures , the transport system in plants
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Vascular can refer to: * blood vessels, the vascular system in animals * vascular tissue Vascular tissue is a complex transporting tissue, formed of more than one cell type, found in vascular plants. The primary components of vascular tissue are the xylem and phloem. These two tissues transport fluid and nutrients internally. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intravascular Fluorescence
Intravascular fluorescence is a catheter-based molecular imaging technique that uses near-infrared fluorescence to detect artery wall autofluorescence (NIRAF) or fluorescence generated by molecular agents injected intravenously (NIRF) . No commercial systems based on intravascular fluorescence are currently on the market, however, significant steps forwards in intravascular fluorescence imaging technology have been made between 2010-2016. It is typically used to detect functional state of artery wall including some known high-risk features of atherosclerosis (e.g., inflammation). It is usually combined with structural imaging modalities such as Intravascular ultrasound and/or Intracoronary optical coherence tomography, to provide functional information in a morphological context. Methods Intravascular fluorescence typically used laser-induced fluorescence to stimulate fluorescence emission of particular vessel wall and plaque components or previously injected molecular agents (i.e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fractional Flow Reserve
Fractional flow reserve (FFR) is a diagnostic technique used in coronary catheterization. FFR measures pressure differences across a coronary artery stenosis (narrowing, usually due to atherosclerosis) to determine the likelihood that the stenosis impedes oxygen delivery to the heart muscle (myocardial ischemia). Fractional flow reserve is defined as the pressure after (distal to) a stenosis relative to the pressure before the stenosis. The result is an absolute number; an FFR of 0.80 means that a given stenosis causes a 20% drop in blood pressure. In other words, FFR expresses the maximal flow down a vessel in the presence of a stenosis compared to the maximal flow in the hypothetical absence of the stenosis. Procedure During coronary catheterization, a catheter is inserted into the femoral (groin) or radial arteries (wrist) using a sheath and guidewire. FFR uses a small sensor on the tip of the wire (commonly a transducer) to measure pressure, temperature and flow to determin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lumen (anatomy)
In biology, a lumen (: lumina) is the inside space of a tubular structure, such as an artery or intestine. It comes . It can refer to: *the interior of a vessel, such as the central space in an artery, vein or capillary through which blood flows *the interior of the gastrointestinal tract *the pathways of the bronchi in the lungs *the interior of renal tubules and urinary collecting ducts *the pathways of the female genital tract, starting with a single pathway of the vagina, splitting up in two lumina in the uterus, both of which continue through the fallopian tubes *the fluid-filled cavity forming in the blastocyst during pre-implantation development called the blastocoel In cell biology, lumen is a membrane-defined space that is found inside several organelles, cellular components, or structures, including thylakoid, endoplasmic reticulum, Golgi apparatus, lysosome, mitochondrion, and microtubule. Transluminal procedures ''Transluminal procedures'' are procedures occur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intravascular Imaging
Intravascular imaging is a catheter based system that allows physicians such as interventional cardiologists to acquire images of diseased vessels from inside the artery. Intravascular imaging provides detailed and accurate measurements of vessel lumen morphology, vessel size, extension of diseased artery segments, vessel size and plaque characteristics. Examples of intravascular imaging modalities are intravascular ultrasound (IVUS) and intracoronary optical coherence tomography (OCT or IVOCT). See also * Fractional flow reserve * Intracoronary Optical Coherence Tomography * intravascular ultrasound Intravascular ultrasound (IVUS) or intravascular echocardiography is a medical imaging methodology using a specially designed catheter with a miniaturized ultrasound probe attached to the distal end of the catheter. The proximal end of the cathe ... References {{Medicine, state=collapsed Vascular procedures Medical imaging ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science (journal)
''Science'' is the peer review, peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, is currently circulated weekly and has a subscriber base of around 130,000. Because institutional subscriptions and online access serve a larger audience, its estimated readership is over 400,000 people. ''Science'' is based in Washington, D.C., United States, with a second office in Cambridge, UK. Contents The major focus of the journal is publishing important original scientific research and research reviews, but ''Science'' also publishes science-related news, opinions on science policy and other matters of interest to scientists and others who are concerned with the wide implications of science and technology. Unlike most scientific journals, which focus on a specific field, ''Science'' and its rival ''Nature (journal), Nature'' cover the full range of List of academ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frequency Domain
In mathematics, physics, electronics, control systems engineering, and statistics, the frequency domain refers to the analysis of mathematical functions or signals with respect to frequency (and possibly phase), rather than time, as in time series. While a time-domain graph shows how a signal changes over time, a frequency-domain graph shows how the signal is distributed within different frequency bands over a range of frequencies. A complex valued frequency-domain representation consists of both the magnitude and the phase of a set of sinusoids (or other basis waveforms) at the frequency components of the signal. Although it is common to refer to the magnitude portion (the real valued frequency-domain) as the frequency response of a signal, the phase portion is required to uniquely define the signal. A given function or signal can be converted between the time and frequency domains with a pair of mathematical operators called transforms. An example is the Fourier transfo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Time Domain
In mathematics and signal processing, the time domain is a representation of how a signal, function, or data set varies with time. It is used for the analysis of mathematical functions, physical signals or time series of economic or environmental data. In the time domain, the independent variable is time, and the dependent variable is the value of the signal. This contrasts with the frequency domain, where the signal is represented by its constituent frequencies. For continuous-time signals, the value of the signal is defined for all real numbers representing time. For discrete-time signals, the value is known at discrete, often equally-spaced, time intervals. It is commonly visualized using a graph where the x-axis represents time and the y-axis represents the signal's value. An oscilloscope is a common tool used to visualize real-world signals in the time domain. Though most precisely referring to time in physics, the term ''time domain'' may occasionally informally ref ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ultrasound
Ultrasound is sound with frequency, frequencies greater than 20 Hertz, kilohertz. This frequency is the approximate upper audible hearing range, limit of human hearing in healthy young adults. The physical principles of acoustic waves apply to any frequency range, including ultrasound. Ultrasonic devices operate with frequencies from 20 kHz up to several gigahertz. Ultrasound is used in many different fields. Ultrasonic devices are used to detect objects and measure distances. Ultrasound imaging or sonography is often used in medicine. In the nondestructive testing of products and structures, ultrasound is used to detect invisible flaws. Industrially, ultrasound is used for cleaning, mixing, and accelerating chemical processes. Animals such as bats and porpoises use ultrasound for locating prey and obstacles. History Acoustics, the science of sound, starts as far back as Pythagoras in the 6th century BC, who wrote on the mathematical properties of String instrument ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Catheter
In medicine, a catheter ( ) is a thin tubing (material), tube made from medical grade materials serving a broad range of functions. Catheters are medical devices that can be inserted in the body to treat diseases or perform a surgical procedure. Catheters are manufactured for specific applications, such as cardiovascular, urological, gastrointestinal, neurovascular and ophthalmic procedures. The process of inserting a catheter is called ''catheterization''. In most uses, a catheter is a thin, flexible tube (''soft'' catheter) though catheters are available in varying levels of stiffness depending on the application. A catheter left inside the body, either temporarily or permanently, may be referred to as an "indwelling catheter" (for example, a peripherally inserted central catheter). A permanently inserted catheter may be referred to as a "permcath" (originally a trademark). Catheters can be inserted into a body cavity, duct, or vessel, brain, skin or adipose tissue. Functional ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
