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Electrotonic Potential
In physiology, electrotonus refers to the passive spread of charge inside a neuron and between cardiac muscle cells or smooth muscle cells. ''Passive'' means that voltage-dependent changes in membrane conductance do not contribute. Neurons and other excitable cells produce two types of electrical potential: * ''Electrotonic'' potential (or graded potential), a non-propagated local potential, resulting from a local change in ionic conductance (e.g. synaptic or sensory that engenders a local current). When it spreads along a stretch of membrane, it becomes exponentially smaller (decrement). * ''Action'' potential, a propagated impulse. Electrotonic potentials represent changes to the neuron's membrane potential that do not lead to the generation of new current by action potentials. However, all action potentials are begun by electrotonic potentials depolarizing the membrane above the threshold potential which converts the electrotonic potential into an action potential. Neurons which ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1223 Graded Potentials-02
1 (one, unit, unity) is a number, numeral, and glyph. It is the first and smallest positive integer of the infinite sequence of natural numbers. This fundamental property has led to its unique uses in other fields, ranging from science to sports, where it commonly denotes the first, leading, or top thing in a group. 1 is the unit of counting or measurement, a determiner for singular nouns, and a gender-neutral pronoun. Historically, the representation of 1 evolved from ancient Sumerian and Babylonian symbols to the modern Arabic numeral. In mathematics, 1 is the multiplicative identity, meaning that any number multiplied by 1 equals the same number. 1 is by convention not considered a prime number. In digital technology, 1 represents the "on" state in binary code, the foundation of computing. Philosophically, 1 symbolizes the ultimate reality or source of existence in various traditions. In mathematics The number 1 is the first natural number after 0. Each natural numbe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sodium
Sodium is a chemical element; it has Symbol (chemistry), symbol Na (from Neo-Latin ) and atomic number 11. It is a soft, silvery-white, highly reactive metal. Sodium is an alkali metal, being in group 1 element, group 1 of the periodic table. Its only stable isotope is 23Na. The free metal does not occur in nature and must be prepared from compounds. Sodium is the Abundance of elements in Earth's crust, sixth most abundant element in the Earth's crust and exists in numerous minerals such as feldspars, sodalite, and halite (NaCl). Many salts of sodium are highly water-soluble: sodium ions have been Leaching (chemistry), leached by the action of water from the Earth, Earth's minerals over eons, and thus sodium and chlorine are the most common dissolved elements by weight in the oceans. Sodium was first isolated by Humphry Davy in 1807 by the electrolysis of sodium hydroxide. Among many other useful sodium compounds, sodium hydroxide (lye) is used in Soap, soap manufac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ribbon Synapse
The ribbon synapse is a type of neuronal synapse characterized by the presence of an electron-dense structure, the synaptic ribbon, that holds vesicles close to the active zone. It is characterized by a tight vesicle-calcium channel coupling that promotes rapid neurotransmitter release and sustained signal transmission. Ribbon synapses undergo a cycle of exocytosis and endocytosis in response to graded changes of membrane potential. It has been proposed that most ribbon synapses undergo a special type of exocytosis based on coordinated multivesicular release. This interpretation has recently been questioned at the inner hair cell ribbon synapse, where it has been instead proposed that exocytosis is described by uniquantal (i.e., univesicular) release shaped by a flickering vesicle fusion pore. These unique features specialize the ribbon synapse to enable extremely fast, precise and sustained neurotransmission, which is critical for the perception of complex senses such as vision ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Action Potential
An action potential (also known as a nerve impulse or "spike" when in a neuron) is a series of quick changes in voltage across a cell membrane. An action potential occurs when the membrane potential of a specific Cell (biology), cell rapidly rises and falls. This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of Membrane potential#Cell excitability, excitable cells, which include animal cells like neurons and myocyte, muscle cells, as well as some plant cells. Certain endocrine cells such as pancreatic beta cells, and certain cells of the anterior pituitary gland are also excitable cells. In neurons, action potentials play a central role in cell–cell interaction, cell–cell communication by providing for—or with regard to saltatory conduction, assisting—the propagation of signals along the neuron's axon toward axon terminal, synaptic boutons situated at the ends of an axon; these signals can then connect wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Partial Differential Equation
In mathematics, a partial differential equation (PDE) is an equation which involves a multivariable function and one or more of its partial derivatives. The function is often thought of as an "unknown" that solves the equation, similar to how is thought of as an unknown number solving, e.g., an algebraic equation like . However, it is usually impossible to write down explicit formulae for solutions of partial differential equations. There is correspondingly a vast amount of modern mathematical and scientific research on methods to numerically approximate solutions of certain partial differential equations using computers. Partial differential equations also occupy a large sector of pure mathematical research, in which the usual questions are, broadly speaking, on the identification of general qualitative features of solutions of various partial differential equations, such as existence, uniqueness, regularity and stability. Among the many open questions are the existence ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alan Lloyd Hodgkin
Sir Alan Lloyd Hodgkin (5 February 1914 – 20 December 1998) was an English physiologist and biophysicist who shared the 1963 Nobel Prize in Physiology or Medicine with Andrew Huxley and John Eccles. Early life and education Hodgkin was born in Banbury, Oxfordshire, on 5 February 1914. He was the oldest of three sons of Quakers George Hodgkin and Mary Wilson Hodgkin. His father was the son of Thomas Hodgkin and had read for the Natural Science Tripos at Cambridge where he had befriended electrophysiologist Keith Lucas. Because of poor eyesight, he was unable to study medicine and eventually ended up working for a bank in Banbury. As members of the Society of Friends, George and Mary opposed the Military Service Act of 1916, which introduced conscription, and had to endure a great deal of abuse from their local community, including an attempt to throw George in one of the town canals. In 1916, George Hodgkin travelled to Armenia as part of an investigation of distress. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William Thomson, 1st Baron Kelvin
William Thomson, 1st Baron Kelvin (26 June 182417 December 1907), was a British mathematician, Mathematical physics, mathematical physicist and engineer. Born in Belfast, he was the Professor of Natural Philosophy (Glasgow), professor of Natural Philosophy at the University of Glasgow for 53 years, where he undertook significant research on the mathematical analysis of electricity, was instrumental in the formulation of the first and second laws of thermodynamics, and contributed significantly to unifying physics, which was then in its infancy of development as an emerging academic discipline. He received the Royal Society's Copley Medal in 1883 and served as its President of the Royal Society, president from 1890 to 1895. In 1892, he became the first scientist to be elevated to the House of Lords. Absolute temperatures are stated in units of kelvin in Lord Kelvin's honour. While the existence of a coldest possible temperature, absolute zero, was known before his work, Kelvin d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cable Theory
In neuroscience, classical cable theory uses mathematical models to calculate the electric current (and accompanying voltage) along passive neurites, particularly the dendrites that receive synaptic inputs at different sites and times. Estimates are made by modeling dendrites and axons as cylinders composed of segments with capacitances c_m and resistances r_m combined in parallel (see Fig. 1). The capacitance of a neuronal fiber comes about because electrostatic forces are acting through the very thin lipid bilayer (see Figure 2). The resistance in series along the fiber r_l is due to the axoplasm's significant resistance to movement of electric charge. History Cable theory in computational neuroscience has roots leading back to the 1850s, when Professor William Thomson (later known as Lord Kelvin) began developing mathematical models of signal decay in submarine (underwater) telegraphic cables. The models resembled the partial differential equations used by Fourier to d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cable Theory Neuron RC Circuit V3
Cable may refer to: Mechanical * Nautical cable, an assembly of three or more ropes woven against the weave of the ropes, rendering it virtually waterproof * Wire rope, a type of rope that consists of several strands of metal wire laid into a helix ** Arresting cable, part of a system used to rapidly decelerate an aircraft as it lands ** Bowden cable, a mechanical cable for transmitting forces * Rope generally, especially a thick, heavy ("cable laid") variety Transmission * Electrical cable, an assembly of one or more wires which may be insulated, used for transmission of electrical power or signals ** Coaxial cable, an electrical cable comprising an inner conductor surrounded by a flexible, tubular insulating layer, coated or surrounded by a tubular conducting shield ** Power cable, a cable used to transmit electrical power ** Submarine communications cable, a cable laid on the sea bed to carry telecommunication signals between land-based stations * Fiber-optic cable, a cable co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Potassium In Biology
Potassium is the main intracellular ion for all types of cells, while having a major role in maintenance of fluid and electrolyte balance. Potassium is necessary for the function of all living cells and is thus present in all plant and animal tissues. It is found in especially high concentrations within plant cells, and in a mixed diet, it is most highly concentrated in fruits. The high concentration of potassium in plants, associated with comparatively very low amounts of sodium there, historically resulted in potassium first being isolated from the ashes of plants (potash), which in turn gave the element its modern name. The high concentration of potassium in plants means that heavy crop production rapidly depletes soils of potassium, and agricultural fertilizers consume 93% of the potassium chemical production of the modern world economy. The functions of potassium and sodium in living organisms are quite different. Animals, in particular, employ sodium and potassium different ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chloride
The term chloride refers to a compound or molecule that contains either a chlorine anion (), which is a negatively charged chlorine atom, or a non-charged chlorine atom covalently bonded to the rest of the molecule by a single bond (). The pronunciation of the word "chloride" is . Chloride salts such as sodium chloride are often soluble in water.Green, John, and Sadru Damji. "Chapter 3." ''Chemistry''. Camberwell, Vic.: IBID, 2001. Print. It is an essential electrolyte located in all body fluids responsible for maintaining acid/base balance, transmitting nerve impulses and regulating liquid flow in and out of cells. Other examples of ionic chlorides include potassium chloride (), calcium chloride (), and ammonium chloride (). Examples of covalent chlorides include methyl chloride (), carbon tetrachloride (), sulfuryl chloride (), and monochloramine (). Electronic properties A chloride ion (diameter 167 pm) is much larger than a chlorine atom (diameter 99 pm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
