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David James (cell Biologist)
David Ernest James (born in Sydney in 1958) is a cell biologist who discovered the glucose transporter GLUT4. He has also been responsible for the molecular dissection of the intracellular trafficking pathways that regulate GLUT4 translocation to the cell surface, the topological mapping of the insulin signal transduction pathway, the creation of a method for studying ''in vivo'' metabolism in small animals, and the use of this method to gain insights into whole-animal fuel metabolism and homeostasis. In 1979 he graduated with a BSc (Hons) from the University of New South Wales, and gained his Ph.D. at the Garvan Institute of Medical Research in 1985. Subsequently he pursued postdoc research at Boston University and Washington University in St. Louis in the USA. In 1993 he returned to Australia, first to Brisbane and then once again at the Garvan Institute. In 2014 he moved to the University of Sydney. He currently holds joint appointments as the Leonard P Ullmann Chair in Mo ...
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Cell Biology
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. Cell biology is the study of structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation. These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fields such ...
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Australian Laureate Fellowship
The Australian Laureate Fellowship is an Australian professorial research fellowship awarded by the Australian Research Council. Up to 17 fellows are chosen each year for five-year awards. Kathleen Fitzpatrick and Georgina Sweet fellowships In 2010, the Australian Research Council created the Kathleen Fitzpatrick and Georgina Sweet Australian Laureate Fellowships. The Kathleen Fitzpatrick fellowship is named for Kathleen Fitzpatrick and honours a woman candidate in a humanities Humanities are academic disciplines that study aspects of human society and culture. In the Renaissance, the term contrasted with divinity and referred to what is now called classics, the main area of secular study in universities at t ... field. The Georgina Sweet fellowship is named for Georgina Sweet and honours a woman in a science or technology discipline. In addition to the funding from the standard Australian laureate fellowship, both of these named fellowships include an additional $2 ...
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Garvan Institute Of Medical Research Alumni
Garvan may refer to: People *Francis Patrick Garvan (1875–1937), American lawyer, president of the Chemical Foundation *Genevieve Garvan Brady (1880–1938), American philanthropist and Papal duchess * Garvan McCarthy (born 1981), retired Irish sportsperson * Gerry Garvan, former Irish footballer and coach who played as a midfielder * John Garvan Murtha (born 1941), United States federal judge * Liz Garvan, camogie player *Noel Garvan, Gaelic football player from Laois in Ireland * Owen Garvan (born 1988), Irish footballer Places * Garvan, Gabrovo Province, village in Gabrovo Province, Bulgaria * Garvan, Silistra Province, village in Sitovo Municipality, Silistra Province, Bulgaria * Garvan, Iran, a village in Sistan and Baluchestan Province, Iran *Garvan, a village in the Konče municipality in eastern North Macedonia *Garvăn, a village in Jijila Commune, Tulcea County, Romania *Garvan, a village in Highland, Scotland * Garvan Woodland Gardens 210 acres of botanical garden by t ...
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University Of Sydney Faculty
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university ...
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Fellows Of The Australian Academy Of Science
The Fellowship of the Australian Academy of Science is made up of about 500 Australian scientists. Scientists judged by their peers to have made an exceptional contribution to knowledge in their field may be elected to Fellowship of the Academy. Fellow A fellow is a concept whose exact meaning depends on context. In learned or professional societies, it refers to a privileged member who is specially elected in recognition of their work and achievements. Within the context of higher education ...s are often denoted using the post-nominal FAA (Fellow of the Australian Academy of Science). A small number of distinguished foreign scientists with substantial connections to Australian science are elected as Corresponding Members. Fellows are appointed for life; this table also contains deceased fellows. Fellows Corresponding Members References *Australian Academy of ScienceFellowship list External links *http://www.asap.unimelb.edu.au/asap_inf.htm – Australian Scien ...
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1958 Births
Events January * January 1 – The European Economic Community (EEC) comes into being. * January 3 – The West Indies Federation is formed. * January 4 ** Edmund Hillary's Commonwealth Trans-Antarctic Expedition completes the third overland journey to the South Pole, the first to use powered vehicles. ** Sputnik 1 (launched on October 4, 1957) falls to Earth from its orbit, and burns up. * January 13 – Battle of Edchera: The Moroccan Army of Liberation ambushes a Spanish patrol. * January 27 – A Soviet-American executive agreement on cultural, educational and scientific exchanges, also known as the "Lacy-Zarubin Agreement, Lacy–Zarubin Agreement", is signed in Washington, D.C. * January 31 – The first successful American satellite, Explorer 1, is launched into orbit. February * February 1 – Egypt and Syria unite, to form the United Arab Republic. * February 6 – Seven Manchester United F.C., Manchester United footballers are among the 21 people killed i ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Australian Biologists
Australian(s) may refer to: Australia * Australia, a country * Australians, citizens of the Commonwealth of Australia ** European Australians ** Anglo-Celtic Australians, Australians descended principally from British colonists ** Aboriginal Australians, indigenous peoples of Australia as identified and defined within Australian law * Australia (continent) ** Indigenous Australians * Australian English, the dialect of the English language spoken in Australia * Australian Aboriginal languages * ''The Australian'', a newspaper * Australiana, things of Australian origins Other uses * Australian (horse), a racehorse * Australian, British Columbia, an unincorporated community in Canada See also * The Australian (other) * Australia (other) * * * Austrian (other) Austrian may refer to: * Austrians, someone from Austria or of Austrian descent ** Someone who is considered an Austrian citizen, see Austrian nationality law * Austrian German dialect * Somet ...
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Charles Perkins Centre
The Charles Perkins Centre (CPC) is an Australian medical research institute, clinic and education hub that primarily focuses on diabetes, cardiovascular disease and obesity, as well as other related conditions. The centre is affiliated with the University of Sydney and is located within the Royal Prince Alfred Hospital health precinct at the campus of the university in Sydney, New South Wales. The centre is named in honour of alumnus Charles Perkins, the first man of Aboriginal descent to graduate from an Australian university. The centre's academic director is Professor Stephen Simpson. Designed by Francis-Jones Morehen Thorp with Building Studio, construction of the 385 million Centre began in 2012 and was officially opened in June 2014. Completed in the Modernist Australian architectural style, the centre was shortlisted for the World's Best Building award in the Higher Education and Research category at the 2015 World Architecture Festival. Many professorial chairs ...
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GLUT 4
Glucose transporter type 4 (GLUT4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the ''SLC2A4'' gene. GLUT4 is the insulin-regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac). The first evidence for this distinct glucose transport protein was provided by David James in 1988. The gene that encodes GLUT4 was cloned and mapped in 1989. At the cell surface, GLUT4 permits the facilitated diffusion of circulating glucose down its concentration gradient into muscle and fat cells. Once within cells, glucose is rapidly phosphorylated by glucokinase in the liver and hexokinase in other tissues to form glucose-6-phosphate, which then enters glycolysis or is polymerized into glycogen. Glucose-6-phosphate cannot diffuse back out of cells, which also serves to maintain the concentration gradient for glucose to passively enter cells. Structure Like all proteins, ...
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Australian Academy Of Science
The Australian Academy of Science was founded in 1954 by a group of distinguished Australians, including Australian Fellows of the Royal Society of London. The first president was Sir Mark Oliphant. The academy is modelled after the Royal Society and operates under a Royal Charter; as such, it is an independent body, but it has government endorsement. The Academy Secretariat is in Canberra, at the Shine Dome. The objectives of the academy are to promote science and science education through a wide range of activities. It has defined four major program areas: :* Recognition of outstanding contributions to science :* Education and public awareness :* Science policy :* International relations The academy also runs the 22 National Committees for Science which provide a forum to discuss issues relevant to all the scientific disciplines in Australia. Origins The Australian National Research Council (ANRC) was established in 1919 for the purpose of representing Australia on the I ...
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GLUT4
Glucose transporter type 4 (GLUT4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the ''SLC2A4'' gene. GLUT4 is the insulin-regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac). The first evidence for this distinct glucose transport protein was provided by David James in 1988. The gene that encodes GLUT4 was cloned and mapped in 1989. At the cell surface, GLUT4 permits the facilitated diffusion of circulating glucose down its concentration gradient into muscle and fat cells. Once within cells, glucose is rapidly phosphorylated by glucokinase in the liver and hexokinase in other tissues to form glucose-6-phosphate, which then enters glycolysis or is polymerized into glycogen. Glucose-6-phosphate cannot diffuse back out of cells, which also serves to maintain the concentration gradient for glucose to passively enter cells. Structure Like all protein ...
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