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Diethyl Phthalate
Diethyl phthalate (DEP) is a phthalate ester. It is a colourless liquid without significant odour but with a bitter disagreeable taste. Synthesis and applications Diethyl phthalate is produced by the reaction of ethanol with phthalic anhydride, in the presence of a strong acid catalyst: It finds some use as a specialist plasticiser in PVC, it has also been used as a blender and fixative in perfume. Biodegradation Biodegradation by microorganisms Biodegradation of DEP in soil occurs by sequential hydrolysis of the two diethyl chains of the phthalate to produce monoethyl phthalate, followed by phthalic acid. This reaction occurs very slowly in an abiotic environment. Thus there exists an alternative pathway of biodegradation which includes transesterification or demethylation by microorganisms, if the soil is also contaminated with methanol, that would produce another three intermediate compounds, ethyl methyl phthalate, dimethyl phthalate and monomethyl phthalate. This bio ...
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Phthalate
Phthalates ( ), or phthalate esters, are esters of phthalic acid. They are mainly used as plasticizers, i.e., substances added to plastics to increase their flexibility, transparency, durability, and longevity. They are used primarily to soften polyvinyl chloride (PVC). While phthalates are commonly used as plasticizers, not all plasticizers are phthalates. The two terms are specific, unique, and not used interchangeably. Lower-molecular-weight phthalates are typically replaced in many products in the United States, Canada, and European Union over health concerns. They are being replaced by higher molecular-weight phthalates as well as non-phthalic plasticizers. Phthalates are commonly ingested in small quantities via the diet. One of the most commonly known phthalates is bis(2-ethylhexyl) phthalate (DEHP). In many countries, DEHP is regulated as a toxin, and is banned from use in broad categories of consumer goods, such as cosmetics, children's toys, medical devices, and fo ...
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Germ Cell
A germ cell is any cell that gives rise to the gametes of an organism that reproduces sexually. In many animals, the germ cells originate in the primitive streak and migrate via the gut of an embryo to the developing gonads. There, they undergo meiosis, followed by cellular differentiation into mature gametes, either eggs or sperm. Unlike animals, plants do not have germ cells designated in early development. Instead, germ cells can arise from somatic cells in the adult, such as the floral meristem of flowering plants. Introduction Multicellular eukaryotes are made of two fundamental cell types: germ and somatic cells. Germ cells produce gametes and are the only cells that can undergo meiosis as well as mitosis. Somatic cells are all the other cells that form the building blocks of the body and they only divide by mitosis. The lineage of germ cells is called the germline. Germ cell specification begins during cleavage in many animals or in the epiblast during gastr ...
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Ethyl Esters
Ethyl may refer to: Arts and entertainment *Ethyl Sinclair, a character in the ''Dinosaurs'' television show Science and technology * Ethyl group, an organic chemistry moiety * Ethyl alcohol (or ethanol) * Ethyl Corporation, a fuel additive company ** Tetraethyllead Tetraethyllead (commonly styled tetraethyl lead), abbreviated TEL, is an organolead compound with the formula lead, Pb(ethyl group, C2H5)4. It was widely used as a fuel additive for much of the 20th century, first being mixed with gasoline begi ...-treated gasoline See also * Ethel (other) {{disambiguation ...
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Bone Resorption
Bone resorption is resorption of bone tissue, that is, the process by which osteoclasts break down the tissue in bones and release the minerals, resulting in a transfer of calcium from bone tissue to the blood. The osteoclasts are multi-nucleated cells that contain numerous mitochondria and lysosomes. These are the cells responsible for the resorption of bone. Osteoblasts are generally present on the outer layer of bone, just beneath the periosteum. Attachment of the osteoclast to the osteon begins the process. The osteoclast then induces an infolding of its cell membrane and secretes collagenase and other enzymes important in the resorption process. High levels of calcium, magnesium, phosphate and products of collagen will be released into the extracellular fluid as the osteoclasts tunnel into the mineralized bone. Osteoclasts are prominent in the tissue destruction found in psoriatic arthritis and rheumatological disorders. The human body is in a constant state of bone re ...
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Royal Netherlands Institute For Sea Research
The Royal Netherlands Institute for Sea Research, also known as NIOZ, in Dutch the Nederlands Instituut voor Onderzoek der Zee, is the Dutch national oceanographic institute. It is located on the island of Texel, and in Yerseke, in the Netherlands. The institute was founded in 1876 as the Zoological Station and in 1960 it was renamed to its current name. NIOZ carries out marine research in the waters of the Netherlands and overseas; it also plays a role in educating students, and it offers research facilities to marine scientists from the Netherlands and other countries worldwide. NIOZ has a longstanding collaboration with Utrecht University, for instance in an interdisciplinary Master’s programme Marine Sciences. NIOZ is part of the institutes organization of the Dutch Research Council The Dutch Research Council (NWO, Dutch: Nederlandse Organisatie voor Wetenschappelijk Onderzoek) is the national research council of the Netherlands. NWO funds thousands of top researchers at ...
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Moulting
In biology, moulting (British English), or molting (American English), also known as sloughing, shedding, or in many invertebrates, ecdysis, is a process by which an animal casts off parts of its body to serve some beneficial purpose, either at specific times of the year, or at specific points in its life cycle. In medieval times, it was also known as "mewing" (from the French verb "muer", to moult), a term that lives on in the name of Britain's Royal Mews where the King's hawks used to be kept during moulting time before becoming horse stables after Tudor times. Moulting can involve shedding the Epidermis (skin), epidermis (skin), pelage (hair, feathers, fur, wool), or other external layer. In some groups, other body parts may be shed, for example, the entire exoskeleton in arthropods, including the wings in some insects. Examples In birds In birds, moulting is the periodic replacement of feathers by shedding old feathers while producing new ones. Feathers are dead struct ...
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Exoskeleton
An exoskeleton () . is a skeleton that is on the exterior of an animal in the form of hardened integument, which both supports the body's shape and protects the internal organs, in contrast to an internal endoskeleton (e.g. human skeleton, that of a human) which is enclosed underneath other soft tissues. Some large, hard and non-flexible protective exoskeletons are known as mollusc shell, shell or armour (anatomy), armour. Examples of exoskeletons in animals include the arthropod exoskeleton, cuticle skeletons shared by arthropods (insects, chelicerates, myriapods and crustaceans) and tardigrades, as well as the corallite, skeletal cups formed by hardened secretion of stony corals, the test (biology), test/tunic of sea squirts and sea urchins, and the prominent mollusc shell shared by snails, bivalvia, clams, tusk shells, chitons and nautilus. Some vertebrate animals, such as the turtle, have both an endoskeleton and a turtle shell, protective exoskeleton. Role Exoskeletons c ...
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Chitin
Chitin (carbon, C8hydrogen, H13oxygen, O5nitrogen, N)n ( ) is a long-chain polymer of N-Acetylglucosamine, ''N''-acetylglucosamine, an amide derivative of glucose. Chitin is the second most abundant polysaccharide in nature (behind only cellulose); an estimated 1 billion tons of chitin are produced each year in the biosphere. It is a primary component of cell walls in fungi (especially filamentous and mushroom-forming fungi), the exoskeletons of arthropods such as crustaceans and insects, the radulae, cephalopod beaks and Gladius (cephalopod), gladii of molluscs and in some nematodes and diatoms. It is also synthesised by at least some fish and lissamphibians. Commercially, chitin is extracted from the shells of crabs, shrimps, shellfish and lobsters, which are major by-products of the seafood industry. The structure of chitin is comparable to cellulose, forming crystalline nanofibrils or whiskers. It is functionally comparable to the protein keratin. Chitin has proved useful ...
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Hepatopancreas
The hepatopancreas, digestive gland or midgut gland is an organ of the digestive tract of arthropods and molluscs. It provides the functions which in mammals are provided separately by the liver and pancreas, including the production of digestive enzymes, and absorption of digested food. Arthropods Arthropods, especially detritivores in the Order Isopoda, Suborder Oniscidea (woodlice), have been shown to be able to store heavy metals in their hepatopancreas. This could lead to bioaccumulation through the food chain and implications for food web destruction, if the accumulation gets high enough in polluted areas; for example, high metal concentrations are seen in spiders of the genus '' Dysdera'' which feed on woodlice, including their hepatopancreas, the major metal storage organ of isopods in polluted sites. Molluscs The hepatopancreas is a centre for lipid metabolism and for storage of lipids in gastropods Gastropods (), commonly known as slugs and snails, belong to a ...
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Toxicological Sciences
''Toxicological Sciences'' is a monthly peer-reviewed scientific journal which covers all aspects of research on toxicology. It is published by Oxford University Press on behalf of the Society of Toxicology. It was established in 1981 as ''Fundamental and Applied Toxicology'' and obtained its current name in 1998. The current editor-in-chief is Jeffrey M. Peters, a professor of molecular toxicology and carcinogenesis at The Pennsylvania State University, and the Managing Editor is Virginia F. Hawkins. The editorial staff also includes Associate Editors in subject areas and an editorial board of topic experts. While its ISO 4 abbreviation is ''Toxicol. Sci.'' it is commonly referred to as ''ToxSci''. Abstracting and indexing The journal is abstracted and indexed in Biological Abstracts, BIOSIS, CAB International, Chemical Abstracts Service, Current Contents, EMBASE, Health & Safety Science Abstracts, Science Citation Index, and Toxicology Abstracts. According to the ''Jou ...
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Toxicology And Applied Pharmacology
''Toxicology and Applied Pharmacology'' is a semi-monthly peer-reviewed scientific journal covering research pertaining to the action of chemicals, drugs, or natural products on animals or humans. The journal covers mechanistic approaches to the physiological, biochemical, cellular, or molecular understanding of toxicologic and pathologic lesions and to methods used to describe these responses. Abstracting and indexing The journal is abstracted and indexed in Index Medicus/MEDLINE/PubMed. According to the ''Journal Citation Reports'', the journal has a 2023 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 3.3. References External links * {{DEFAULTSORT:Toxicology And Applied Pharmacology Semi-monthly journals Elsevier academic journals English-language j ...
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