DCMP Deaminase

	DCMP Deaminase dCMP deaminase (, ''deoxycytidylate deaminase'', ''deoxy-CMP-deaminase'', ''deoxycytidylate aminohydrolase'', ''deoxycytidine monophosphate deaminase'', ''deoxycytidine-5'-phosphate deaminase'', ''deoxycytidine-5'-monophosphate aminohydrolase'') is an enzyme which converts deoxycytidylic acid to deoxyuridylic acid. Image:DCMP chemical structure.png, Deoxycytidine monophosphate Image:DUMP chemical structure.png, Deoxyuridine monophosphate References External links * {{Portal bar, Biology, border=no EC 3.5.4 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Deoxycytidylic Acid Deoxycytidine monophosphate (dCMP), also known as deoxycytidylic acid or deoxycytidylate in its conjugate acid and conjugate base forms, respectively, is a deoxynucleotide and one of the four monomers that make up DNA. In a DNA double helix, it will base pair with deoxyguanosine monophosphate. Medical use Deoxycytidine monophosphate is a molecule of interest in treating genetic disorders such as thymidine kinase 2 (''TK2'') deficiency. In the case of ''TK2'' deficiency, dCMP in conjunction with deoxythymidine monophosphate (dTMP) to bypass the deficiency in the ''TK2'' enzyme. Additionally dCMP is an indicator of several metabolite deficiency pathways such as UMP synthase deficiency or orotic aciduria. See also * Cytidine monophosphate Cytidine monophosphate, also known as 5'-cytidylic acid or simply cytidylate, and abbreviated CMP, is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid with the nucleoside cytidine. CMP consists of the phosphate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Deoxyuridylic Acid Deoxyuridine monophosphate (dUMP), also known as deoxyuridylic acid or deoxyuridylate in its conjugate acid and conjugate base forms, respectively, is a deoxynucleotide. It is an intermediate in the metabolism of deoxyribonucleotides. Biosynthesis Deoxyuridine monophosphate (dUMP) is the deoxygenated form of uridine monophosphate (UMP), and is the precursor to deoxythymidine monophosphate (dTMP), a component of DNA nucleotide biosynthesis. By replacing the hydroxyl group at the 2' carbon of ribose with a hydrogen, UMP becomes deoxygenated to dUMP. The synthesis of deoxyuridine monophosphate (dUMP) is a multi-step process that begins with uridine monophosphate (UMP), the product of pyrimidine biosynthesis. The enzyme nucleoside monophosphate kinase converts UMP and ATP to uridine diphosphate (UDP) and ADP. In the presence of excess ATP, the enzyme ribonucleotide reductase initiates a chain reaction with UDP, which catalyzes the formation of deoxyuridine diphosphate (dUDP), w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Deoxycytidine Monophosphate Deoxycytidine monophosphate (dCMP), also known as deoxycytidylic acid or deoxycytidylate in its conjugate acid and conjugate base forms, respectively, is a deoxynucleotide and one of the four monomers that make up DNA. In a DNA double helix, it will base pair with deoxyguanosine monophosphate. Medical use Deoxycytidine monophosphate is a molecule of interest in treating genetic disorders such as thymidine kinase 2 (''TK2'') deficiency. In the case of ''TK2'' deficiency, dCMP in conjunction with deoxythymidine monophosphate (dTMP) to bypass the deficiency in the ''TK2'' enzyme. Additionally dCMP is an indicator of several metabolite deficiency pathways such as UMP synthase deficiency or orotic aciduria. See also * Cytidine monophosphate Cytidine monophosphate, also known as 5'-cytidylic acid or simply cytidylate, and abbreviated CMP, is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid with the nucleoside cytidine. CMP consists of the phosphate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Deoxyuridine Monophosphate Deoxyuridine monophosphate (dUMP), also known as deoxyuridylic acid or deoxyuridylate in its conjugate acid and conjugate base forms, respectively, is a deoxynucleotide. It is an intermediate in the metabolism of deoxyribonucleotides. Biosynthesis Deoxyuridine monophosphate (dUMP) is the deoxygenated form of uridine monophosphate (UMP), and is the precursor to deoxythymidine monophosphate (dTMP), a component of DNA nucleotide biosynthesis. By replacing the hydroxyl group at the 2' carbon of ribose with a hydrogen, UMP becomes deoxygenated to dUMP. The synthesis of deoxyuridine monophosphate (dUMP) is a multi-step process that begins with uridine monophosphate (UMP), the product of pyrimidine biosynthesis. The enzyme nucleoside monophosphate kinase converts UMP and ATP to uridine diphosphate (UDP) and ADP. In the presence of excess ATP, the enzyme ribonucleotide reductase initiates a chain reaction with UDP, which catalyzes the formation of deoxyuridine diphosphate (dUDP), ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]