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Cryo- is from the Ancient Greek κρύος (krúos, “ ice, icy cold, chill, frost”). Uses of the prefix Cryo- include: Physics and geology * Cryogenics, the study of the production and behaviour of materials at very low temperatures and the study of producing extremely low temperatures * Cryoelectronics, the study of superconductivity under cryogenic conditions and its applications * Cryosphere, those portions of Earth's surface where water ice naturally occurs * Cryotron, a switch that uses superconductivity * Cryovolcano, a theoretical type of volcano that erupts volatiles instead of molten rock Biology and medicine * Cryobiology, the branch of biology that studies the effects of low temperatures on living things * Cryonics, the low-temperature preservation of people who cannot be sustained by contemporary medicine * Cryoprecipitate, a blood-derived protein product used to treat some bleeding disorders * Cryotherapy, medical treatment using cold ** Cryoablation, tissue r ...
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Cryogenics
In physics, cryogenics is the production and behaviour of materials at very low temperatures. The 13th IIR International Congress of Refrigeration (held in Washington DC in 1971) endorsed a universal definition of “cryogenics” and “cryogenic” by accepting a threshold of 120 K (or –153 °C) to distinguish these terms from the conventional refrigeration. This is a logical dividing line, since the normal boiling points of the so-called permanent gases (such as helium, hydrogen, neon, nitrogen, oxygen, and normal air) lie below 120K while the Freon refrigerants, hydrocarbons, and other common refrigerants have boiling points above 120K. The U.S. National Institute of Standards and Technology considers the field of cryogenics as that involving temperatures below -153 Celsius (120K; -243.4 Fahrenheit) Discovery of superconducting materials with critical temperatures significantly above the boiling point of nitrogen has provided new interest in reliable, low cost meth ...
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Cryoelectronics
In electronics, cryoelectronics or cryolectronics is the study of superconductivity under cryogenic conditions and its applications. It is also described as the operation of power electronic devices at cryogenic temperatures. Practical applications of this field is quite broad, although it is particularly useful in areas where cryogenic environment exists such as superconducting technologies and spacecraft A spacecraft is a vehicle or machine designed to fly in outer space. A type of artificial satellite, spacecraft are used for a variety of purposes, including communications, Earth observation, meteorology, navigation, space colonization, p ... design. It also became a special branch of cryophysics and cryotechnics and plays a role in operations that require high resolution and precision measurements. Cryoelectronic devices include the SQUIDs or the superconducting quantum interference devices, which represent magnetic sensors of highest sensitivity. They serve as ...
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Cryosphere
] The cryosphere (from the Ancient Greek, Greek ''kryos'', "cold", "frost" or "ice" and ''sphaira'', "globe, ball") is an all-encompassing term for those portions of Earth's surface where water is in solid form, including sea ice, lake ice, river ice, snow cover, glaciers, ice caps, ice sheets, and frozen ground (which includes permafrost). Thus, there is a wide overlap with the hydrosphere. The cryosphere is an integral part of the global climate system with important linkages and feedbacks generated through its influence on surface energy and moisture fluxes, clouds, precipitation, hydrology, atmospheric and oceanic circulation. Through these feedback processes, the cryosphere plays a significant role in the global climate and in climate model response to global changes. Approximately 10% of the Earth's surface is covered by ice, but this is rapidly decreasing. The term ''deglaciation'' describes the retreat of cryospheric features. Cryology is the study of cryospheres. S ...
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Cryotron
The cryotron is a switch that operates using superconductivity. The cryotron works on the principle that magnetic fields destroy superconductivity. This simple device consists of two superconducting wires (e.g. tantalum and niobium) with different critical temperature (Tc). The cryotron was invented by Dudley Allen Buck of the Massachusetts Institute of Technology Lincoln Laboratory. As described by Buck, a straight wire of tantalum (having lower Tc) is wrapped around with a wire of niobium in a single layer coil. Both wires are electrically isolated from each other. When this device is immersed in a liquid helium bath both wires become superconducting and hence offer no resistance to the passage of electric current. Tantalum in superconducting state can carry large amount of current as compared to its normal state. Now when current is passed through the niobium coil (wrapped around tantalum) it produces a magnetic field, which in turn reduces (kills) the superconductivity of the ...
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Cryovolcano
A cryovolcano (sometimes informally called an ice volcano) is a type of volcano that erupts volatiles such as water, ammonia or methane into an extremely cold environment that is at or below their freezing point. The process of formation is known as cryovolcanism. Collectively referred to as cryomagma, cryolava or ice-volcanic melt, these substances are usually liquids and can form plumes, but can also be in vapour form. After the eruption, cryomagma is expected to condense to a solid form when exposed to the very low surrounding temperature. Cryovolcanoes may potentially form on icy moons and other objects with abundant water past the Solar System's snow line (such as Pluto). A number of features have been identified as possible cryovolcanoes on Pluto, Titan and Ceres, and a subset of domes on Europa may have cryovolcanic origins. In addition, although they are not known to form volcanoes, ice geysers have been observed on Enceladus and potentially Triton. One potential ene ...
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Cryobiology
Cryobiology is the branch of biology that studies the effects of low temperatures on living things within Earth's cryosphere or in science. The word cryobiology is derived from the Greek words κρῧος ryos "cold", βίος ios "life", and λόγος ogos "word". In practice, cryobiology is the study of biological material or systems at temperatures below normal. Materials or systems studied may include proteins, cells, tissues, organs, or whole organisms. Temperatures may range from moderately hypothermic conditions to cryogenic temperatures. Areas of study At least six major areas of cryobiology can be identified: 1) study of cold-adaptation of microorganisms, plants ( cold hardiness), and animals, both invertebrates and vertebrates (including hibernation), 2) cryopreservation of cells, tissues, gametes, and embryos of animal and human origin for (medical) purposes of long-term storage by cooling to temperatures below the freezing point of water. This usually requir ...
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Cryonics
Cryonics (from el, κρύος ''kryos'' meaning 'cold') is the low-temperature freezing (usually at ) and storage of human remains, with the speculative hope that resurrection may be possible in the future. Cryonics is regarded with skepticism within the mainstream scientific community. It is generally viewed as a pseudoscience, and its practice has been characterized as quackery. Cryonics procedures can begin only after the "patients" are clinically and legally dead. Cryonics procedures may begin within minutes of death, and use cryoprotectants to prevent ice formation during cryopreservation. It is, however, not possible for a corpse to be reanimated after undergoing vitrification, as this causes damage to the brain including its neural circuits. The first corpse to be frozen was that of James Bedford in 1967. As of 2014, about 250 dead bodies had been cryopreserved in the United States, and 1,500 people had made arrangements for cryopreservation of their corpses. Critics ...
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Cryoprecipitate
Cryoprecipitate, also called cryo for short, is a frozen blood product prepared from blood plasma. To create cryoprecipitate, fresh frozen plasma thawed to 1–6 °C is then centrifuged and the precipitate is collected. The precipitate is resuspended in a small amount of residual plasma (generally 10–15 mL) and is then re-frozen for storage. It is often transfused to adults as two 5-unit pools instead of as a single product. One of the most important constituents is factor VIII (also called antihaemophilic factor or AHF), which is why cryoprecipitate is sometimes called cryoprecipitated antihaemophilic factor or cryoprecipitated AHF. In many clinical contexts, use of whole cryoprecipitate has been replaced with use of clotting factor concentrates made therefrom (where available), but the whole form is still routinely stocked by many, if not most, hospital blood banks. Cryo can be stored at −18 °C or colder for 12 months from the original collection date. After tha ...
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Cryotherapy
Cryotherapy, sometimes known as cold therapy, is the local or general use of low temperatures in medical therapy. Cryotherapy may be used to treat a variety of tissue lesions. The most prominent use of the term refers to the surgical treatment, specifically known as cryosurgery or cryoablation. Cryosurgery is the application of extremely low temperatures to destroy abnormal or diseased tissue and is used most commonly to treat skin conditions. Cryotherapy is used in an effort to relieve muscle pain, sprains and swelling after soft tissue damage or surgery. For decades, it has been commonly used to accelerate recovery in athletes after exercise. Cryotherapy decreases the temperature of tissue surface to minimize hypoxic cell death, edema accumulation, and muscle spasms, all of which ultimately alleviate discomfort and inflammation. It can be a range of treatments from the application of ice packs or immersion in ice baths (generally known as cold therapy), to the use of cold chamb ...
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Cryoablation
Cryoablation is a process that uses extreme cold to destroy tissue. Cryoablation is performed using hollow needles (cryoprobes) through which cooled, thermally conductive, fluids are circulated. Cryoprobes are positioned adjacent to the target in such a way that the freezing process will destroy the diseased tissue. Once the probes are in place, the attached cryogenic freezing unit removes heat from ("cools") the tip of the probe and by extension from the surrounding tissues. Ablation occurs in tissue that has been frozen by at least three mechanisms: # formation of ice crystals within cells thereby disrupting membranes, and interrupting cellular metabolism among other processes; # coagulation of blood thereby interrupting bloodflow to the tissue in turn causing ischemia and cell death; and # induction of apoptosis, the so-called programmed cell death cascade. The most common application of cryoablation is to ablate solid tumors found in the lung, liver, breast, kidney and prosta ...
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Cryosurgery
Cryosurgery is the use of extreme cold in surgery to destroy abnormal or diseased tissue; thus, it is the surgical application of cryoablation. The term comes from the Greek words cryo (κρύο) ("icy cold") and surgery (''cheirourgiki'' – χειρουργική) meaning "hand work" or "handiwork". Cryosurgery has been historically used to treat a number of diseases and disorders, especially a variety of benign and malignant skin conditions. Uses Warts, moles, skin tags, solar keratoses, molluscum, Morton's neuroma and small skin cancers are candidates for cryosurgical treatment. Several internal disorders are also treated with cryosurgery, including liver cancer, prostate cancer, lung cancer, oral cancers, cervical disorders and, more commonly in the past, hemorrhoids. Soft tissue conditions such as plantar fasciitis (jogger's heel) and fibroma (benign excrescence of connective tissue) can be treated with cryosurgery. Cryosurgery works by taking advantage of the des ...
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Cryo-electron Microscopy
Cryogenic electron microscopy (cryo-EM) is a cryomicroscopy technique applied on samples cooled to cryogenic temperatures. For biological specimens, the structure is preserved by embedding in an environment of vitreous ice. An aqueous sample solution is applied to a grid-mesh and plunge-frozen in liquid ethane or a mixture of liquid ethane and propane. While development of the technique began in the 1970s, recent advances in detector technology and software algorithms have allowed for the determination of biomolecular structures at near-atomic resolution. This has attracted wide attention to the approach as an alternative to X-ray crystallography or NMR spectroscopy for macromolecular structure determination without the need for crystallization. In 2017, the Nobel Prize in Chemistry was awarded to Jacques Dubochet, Joachim Frank, and Richard Henderson "for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution." ''Nature ...
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