Carcinogenic Parasite
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Carcinogenic Parasite
Carcinogenic parasites are parasitic organisms that depend on other organisms (called hosts) for their survival, and cause cancer in such hosts. Three species of flukes (trematodes) are medically-proven carcinogenic parasites, namely the urinary blood fluke (''Schistosoma haematobium''), the Southeast Asian liver fluke (''Opisthorchis viverrini'') and the Chinese liver fluke (''Clonorchis sinensis''). ''S. haematobium'' is prevalent in Africa and the Middle East, and is the leading cause of bladder cancer (only next to tobacco smoking). ''O. viverrini'' and ''C. sinensis'' are both found in eastern and southeastern Asia, and are responsible for cholangiocarcinoma (cancer of the bile ducts). The International Agency for Research on Cancer declared them in 2009 as a Group 1 biological carcinogens in humans. Other parasites are also linked to various cancers. Among protozoan parasites, ''Toxoplasma gondii'', ''Cryptosporidium parvum'', ''Trichomonas vaginalis'' and ''Theileria'' ar ...
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Parasitism
Parasitism is a close relationship between species, where one organism, the parasite, lives on or inside another organism, the host, causing it some harm, and is adapted structurally to this way of life. The entomologist E. O. Wilson has characterised parasites as "predators that eat prey in units of less than one". Parasites include single-celled protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the broomrapes. There are six major parasitic strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism (by contact), trophicallytransmitted parasitism (by being eaten), vector-transmitted parasitism, parasitoidism, and micropredation. One major axis of classification concerns invasiveness: an endoparasite lives inside the hos ...
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Strongyloides Stercoralis
''Strongyloides stercoralis'' is a human pathogenic parasitism, parasitic nematode, roundworm causing the disease strongyloidiasis. Its common name in the US is threadworm. In the UK and Australia, however, the term ''threadworm'' can also refer to nematodes of the genus ''Enterobius'', otherwise known as Pinworm (parasite), pinworms. The ''Strongyloides stercoralis'' nematode can parasitize humans. The adult parasitic stage lives in tunnels in the mucosa of the small intestine. The genus ''Strongyloides'' contains 53 species, and ''S. stercoralis'' is the type species. ''S. stercoralis'' has been reported in other mammals, including cats and dogs. However, it seems that the species in dogs is typically not ''S. stercoralis'', but the related species ''S. canis''. Non-human primates are more commonly infected with ''S. fuelleborni'' and ''S. cebus'', although ''S. stercoralis'' has been reported in captive primates. Other species of ''Strongyloides'' that are naturally parasitic ...
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Calcification
Calcification is the accumulation of calcium salts in a body tissue. It normally occurs in the formation of bone, but calcium can be deposited abnormally in soft tissue,Miller, J. D. Cardiovascular calcification: Orbicular origins. ''Nature Materials'' 12, 476-478 (2013). causing it to harden. Calcifications may be classified on whether there is mineral balance or not, and the location of the calcification. Calcification may also refer to the processes of normal mineral deposition in biological systems, such as the formation of stromatolites or mollusc shells (see Biomineralization). Signs and symptoms Calcification can manifest itself in many ways in the body depending on the location. In the pulpal structure of a tooth, calcification often presents asymptomatically, and is diagnosed as an incidental finding during radiographic interpretation. Individual teeth with calcified pulp will typically respond negatively to vitality testing; teeth with calcified pulp often lack se ...
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Haematuria
Hematuria or haematuria is defined as the presence of blood or red blood cells in the urine. “Gross hematuria” occurs when urine appears red, brown, or tea-colored due to the presence of blood. Hematuria may also be subtle and only detectable with a microscope or laboratory test. Blood that enters and mixes with the urine can come from any location within the urinary system, including the kidney, ureter, urinary bladder, urethra, and in men, the prostate. Common causes of hematuria include urinary tract infection (UTI), kidney stones, viral illness, trauma, bladder cancer, and exercise. These causes are grouped into glomerular and non-glomerular causes, depending on the involvement of the glomerulus of the kidney. But not all red urine is hematuria. Other substances such as certain medications and foods (e.g. blackberries, beets, food dyes) can cause urine to appear red. Menstruation in women may also cause the appearance of hematuria and may result in a positive urine dipstick ...
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Urinary Bladder
The urinary bladder, or simply bladder, is a hollow organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination. In humans the bladder is a distensible organ that sits on the pelvic floor. Urine enters the bladder via the ureters and exits via the urethra. The typical adult human bladder will hold between 300 and (10.14 and ) before the urge to empty occurs, but can hold considerably more. The Latin phrase for "urinary bladder" is ''vesica urinaria'', and the term ''vesical'' or prefix ''vesico -'' appear in connection with associated structures such as vesical veins. The modern Latin word for "bladder" – ''cystis'' – appears in associated terms such as cystitis (inflammation of the bladder). Structure In humans, the bladder is a hollow muscular organ situated at the base of the pelvis. In gross anatomy, the bladder can be divided into a broad , a body, an apex, and a neck. The apex (also called the vertex) is directed fo ...
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Venous Plexus
In vertebrates, a venous plexus is a normal congregation anywhere in the body of multiple veins. A list of venous plexuses: * Basilar plexus * Batson venous plexus * Internal vertebral venous plexuses * Pterygoid plexus * Submucosal venous plexus of the nose * Uterine venous plexus * Vaginal venous plexus * Venous plexus of hypoglossal canal * Vesical venous plexus * Soleal venous plexus * Pampiniform venous plexus * Prostatic venous plexus * Rectal venous plexus The rectal venous plexus (or hemorrhoidal plexus) surrounds the rectum, and communicates in front with the vesical venous plexus in the male, and the vaginal venous plexus in the female. A free communication between the portal and systemic venous ... References Veins {{Circulatory-stub ...
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Schistosomiasis
Schistosomiasis, also known as snail fever, bilharzia, and Katayama fever, is a disease caused by parasitic flatworms called schistosomes. The urinary tract or the intestines may be infected. Symptoms include abdominal pain, diarrhea, bloody stool, or blood in the urine. Those who have been infected for a long time may experience liver damage, kidney failure, infertility, or bladder cancer. In children, it may cause poor growth and learning difficulty. The disease is spread by contact with fresh water contaminated with the parasites. These parasites are released from infected freshwater snails. The disease is especially common among children in developing countries, as they are more likely to play in contaminated water. Other high-risk groups include farmers, fishermen, and people using unclean water during daily living. It belongs to the group of helminth infections. Diagnosis is by finding eggs of the parasite in a person's urine or stool. It can also be confirmed ...
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Trematode
Trematoda is a class of flatworms known as flukes. They are obligate internal parasites with a complex life cycle requiring at least two hosts. The intermediate host, in which asexual reproduction occurs, is usually a snail. The definitive host, where the flukes sexually reproduce, is a vertebrate. Infection by trematodes can cause disease in all five traditional vertebrate classes: mammals, birds, amphibians, reptiles, and fish. Etymology Trematodes are commonly referred to as flukes. This term can be traced back to the Old English name for flounder, and refers to the flattened, rhomboidal shape of the organisms. Taxonomy There are 18,000 to 24,000 known species of trematodes, divided into two subclasses — the Aspidogastrea and the Digenea. Aspidogastrea is the smaller subclass, comprising 61 species. These flukes mainly infect bivalves and bony fishes.https://www.biotaxa.org/Zootaxa/article/view/zootaxa.3918.3.2 Digenea — which comprise the majority of trematodes ...
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Digenea
Digenea (Gr. ''Dis'' – double, ''Genos'' – race) is a class of trematodes in the Platyhelminthes phylum, consisting of parasitic flatworms (known as ''flukes'') with a syncytial tegument and, usually, two suckers, one ventral and one oral. Adults commonly live within the digestive tract, but occur throughout the organ systems of all classes of vertebrates. Once thought to be related to the Monogenea, it is now recognised that they are closest to the Aspidogastrea and that the Monogenea are more closely allied with the Cestoda. Around 6,000 species have been described to date. Morphology Key features Characteristic features of the Digenea include a syncytial tegument; that is, a tegument where the junctions between cells are broken down and a single continuous cytoplasm surrounds the entire animal. A similar tegument is found in other members of the Neodermata; a group of platyhelminths comprising the Digenea, Aspidogastrea, Monogenea and Cestoda. Digeneans possess a vermif ...
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Carcinoma
Carcinoma is a malignancy that develops from epithelial cells. Specifically, a carcinoma is a cancer that begins in a tissue that lines the inner or outer surfaces of the body, and that arises from cells originating in the endodermal, mesodermal or ectodermal germ layer during embryogenesis. Carcinomas occur when the DNA of a cell is damaged or altered and the cell begins to grow uncontrollably and become malignant. It is from the el, καρκίνωμα, translit=karkinoma, lit=sore, ulcer, cancer (itself derived from meaning ''crab''). Classification As of 2004, no simple and comprehensive classification system has been devised and accepted within the scientific community. Traditionally, however, malignancies have generally been classified into various types using a combination of criteria, including: The cell type from which they start; specifically: * Epithelial cells ⇨ carcinoma * Non-hematopoietic mesenchymal cells ⇨ sarcoma * Hematopoietic cells ** Bone mar ...
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Reginald Harrison
Reginald Harrison FRCS (24 August 1837 – 28 February 1908) was a British surgeon, sometime vice-president and Member of the Council of the Royal College of Surgeons and Consulting Surgeon to St Peter's Hospital. Life Harrison was educated at Rossall School, Lancashire, and after a short period of probation at the Stafford general hospital, he entered St. Bartholomew's Hospital, London, qualifying in 1859. In 1866 he returned to Lancashire to take up an appointment as assistant physician to the Liverpool Royal Infirmary becoming full surgeon in 1874, later to specialise in diseases of the male genito-urinary system.Reginald Harrison (1837–1908). Nature 140, 310–311 (1937). https://doi.org/10.1038/140310d0 In 1889 he returned to London as surgeon to St. Peter's Hospital for Stone and Other Urinary Diseases. He was the author of ''Surgical Disorders of the Urinary Organs'', which became a standard text-book, and ''The Use of the Ambulance in Civil Practice'', having take ...
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Robert Thomson Leiper
Robert Thomson Leiper (17 April 1881 – 21 May 1969) FRS CMG was a British parasitologist and helminthologist. Early life and education Leiper was born on 17 April 1881 in Witch Road, Kilmarnock, Scotland; the eldest of three children of John Leiper (died 1895), tailor, and his wife, Jessie Aird. The family moved to England shortly after he was born. He was educated at Warwick School, spending time at the Warwick Technical College to further his studies in science. He spent a year at Mason Science College (which later became the University of Birmingham), matriculating in physics, mathematics, English and Latin. He then entered the University of Glasgow to study medicine, at which he excelled, winning awards such as the John Hunter Medal and the Senior Arnott Prize in the field; graduating in 1904. Career From an early age Leiper was devoted to helminthology, the study of parasitic flatworms; while still an undergraduate, at the age of 21, he discovered an undocumented turbe ...
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