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Cantharidin
Cantharidin is an odorless, colorless fatty substance of the terpenoid class, which is secreted by many species of blister beetles. It is a burn agent or a poison in large doses, but preparations containing it were historically used as aphrodisiacs (Spanish fly). In its natural form, cantharidin is secreted by the male blister beetle and given to the female as a copulatory gift during mating. Afterwards, the female beetle covers her eggs with it as a defense against predators. Poisoning from cantharidin is a significant veterinary concern, especially in horses, but it can also be poisonous to humans if taken internally (where the source is usually experimental self-exposure). Externally, cantharidin is a potent vesicant (blistering agent), exposure to which can cause severe chemical burns. Properly dosed and applied, the same properties have also been used therapeutically, for instance for treatment of skin conditions such as molluscum contagiosum infection of the skin. Cantharidi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cantharidin Biosynthesis2
Cantharidin is an odorless, colorless fatty substance of the terpenoid class, which is secreted by many species of blister beetles. It is a burn agent or a poison in large doses, but preparations containing it were historically used as aphrodisiacs (Spanish fly). In its natural form, cantharidin is secreted by the male blister beetle and given to the female as a copulatory gift during mating. Afterwards, the female beetle covers her eggs with it as a defense against predators. Poisoning from cantharidin is a significant veterinary concern, especially in horses, but it can also be poisonous to humans if taken internally (where the source is usually experimental self-exposure). Externally, cantharidin is a potent vesicant (blistering agent), exposure to which can cause severe chemical burns. Properly dosed and applied, the same properties have also been used therapeutically, for instance for treatment of skin conditions such as molluscum contagiosum infection of the skin. Cantharidi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lytta Vesicatoria
The Spanish fly (''Lytta vesicatoria'') is an aposematic emerald-green beetle in the blister beetle family (Meloidae). It is distributed across Eurasia. The species and others in its family were used in traditional apothecary preparations as "Cantharides". The insect is the source of the terpenoid cantharidin, a toxic blistering agent once used as an exfoliating agent, anti-rheumatic drug and an aphrodisiac. The substance has also found culinary use in some blends of the North African spice mix ''ras el hanout''. Its various supposed benefits have been responsible for accidental poisonings. Etymology and taxonomy The generic name is from the Greek λύττα (''lytta''), meaning martial rage, raging madness, Bacchic frenzy, or rabies. The specific name is derived from Latin ''vesica'', blister. ''Lytta vesicatoria'' was formerly named ''Cantharis vesicatoria'', although the genus ''Cantharis'' is in an unrelated family, Cantharidae, the soldier beetles. It was class ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spanish Fly
The Spanish fly (''Lytta vesicatoria'') is an aposematic emerald-green beetle in the blister beetle family (Meloidae). It is distributed across Eurasia. The species and others in its family were used in traditional apothecary preparations as "Cantharides". The insect is the source of the terpenoid cantharidin, a toxic blistering agent once used as an exfoliating agent, anti-rheumatic drug and an aphrodisiac. The substance has also found culinary use in some blends of the North African spice mix ''ras el hanout''. Its various supposed benefits have been responsible for accidental poisonings. Etymology and taxonomy The generic name is from the Greek λύττα (''lytta''), meaning martial rage, raging madness, Bacchic frenzy, or rabies. The specific name is derived from Latin ''vesica'', blister. ''Lytta vesicatoria'' was formerly named ''Cantharis vesicatoria'', although the genus ''Cantharis'' is in an unrelated family, Cantharidae, the soldier beetles. It was class ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blister Beetle
Blister beetles are beetles of the family Meloidae, so called for their defensive secretion of a blistering agent, cantharidin. About 7,500 species are known worldwide. Many are conspicuous and some are aposematically colored, announcing their toxicity to would-be predators. Description Blister beetles are hypermetamorphic, going through several larval stages, the first of which is typically a mobile triungulin. The larvae are insectivorous, mainly attacking bees, though a few feed on grasshopper eggs. While sometimes considered parasitoids, in general, the meloid larva apparently consumes the immature host along with its provisions, and can often survive on the provisions alone; thus it is not an obligatory parasitoid, but rather a facultative parasitoid, or simply a kleptoparasite. The adults sometimes feed on flowers and leaves of plants of such diverse families as the Amaranthaceae, Asteraceae, Fabaceae, and Solanaceae. Cantharidin, a poisonous chemical that causes bl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vesicant
A blister agent (or vesicant), is a chemical compound that causes severe skin, eye and mucosal pain and irritation. They are named for their ability to cause severe chemical burns, resulting in painful water blisters on the bodies of those affected. Although the term is often used in connection with large-scale burns caused by chemical spills or chemical warfare agents, some naturally occurring substances such as are also blister-producing agents (vesicants). [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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