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CADUCEUS (expert System)
CADUCEUS was a medical expert system finished in the mid-1980s (first begun in the 1970s- it took a long time to build the knowledge base) by Harry Pople (of the University of Pittsburgh), building on Pople's years of interviews with Dr. Jack Meyers, one of the top internal medicine diagnosticians and a professor at the University of Pittsburgh. Their motivation was to improve on MYCIN (which focused on blood-borne infectious bacteria) to focus on more comprehensive issues than a narrow field like blood poisoning (though it would do it in a similar manner); instead embracing all internal medicine. CADUCEUS eventually could diagnose up to 1000 different diseases. While CADUCEUS worked using an inference engine similar to MYCIN's, it made a number of changes (like incorporating abductive reasoning) to deal with the additional complexity of internal disease- there can be a number of simultaneous diseases, and data is generally flawed and scarce. CADUCEUS has been described as the ...
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Expert System
In artificial intelligence, an expert system is a computer system emulating the decision-making ability of a human expert. Expert systems are designed to solve complex problems by reasoning through bodies of knowledge, represented mainly as if–then rules rather than through conventional procedural code. The first expert systems were created in the 1970s and then proliferated in the 1980s. Expert systems were among the first truly successful forms of artificial intelligence (AI) software. An expert system is divided into two subsystems: the inference engine and the knowledge base. The knowledge base represents facts and rules. The inference engine applies the rules to the known facts to deduce new facts. Inference engines can also include explanation and debugging abilities. History Early development Soon after the dawn of modern computers in the late 1940s and early 1950s, researchers started realizing the immense potential these machines had for modern society. One ...
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Abductive Reasoning
Abductive reasoning (also called abduction,For example: abductive inference, or retroduction) is a form of logical inference formulated and advanced by American philosopher Charles Sanders Peirce beginning in the last third of the 19th century. It starts with an observation or set of observations and then seeks the simplest and most likely conclusion from the observations. This process, unlike deductive reasoning, yields a plausible conclusion but does not positively verify it. Abductive conclusions are thus qualified as having a remnant of uncertainty or doubt, which is expressed in retreat terms such as "best available" or "most likely". One can understand abductive reasoning as inference to the best explanation, although not all usages of the terms ''abduction'' and ''inference to the best explanation'' are exactly equivalent. In the 1990s, as computing power grew, the fields of law, computer science, and artificial intelligence researchFor examples, seeAbductive Inference i ...
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Medical Expert Systems
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an anci ...
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Karen A
Karen may refer to: * Karen (name), a given name and surname * Karen (slang), a term and meme for a demanding woman displaying certain behaviors People * Karen people, an ethnic group in Myanmar and Thailand ** Karen languages or Karenic languages * House of Karen, a historical feudal family of Tabaristan, Iran * Karen (singer), Danish R&B singer Places * Karen, Kenya, a suburb of Nairobi * Karen City or Hualien City, Taiwan * Karen Hills or Karen Hills, Myanmar * Karen State, a state in Myanmar Film and television * ''Karen'' (1964 TV series), an American sitcom * ''Karen'' (1975 TV series), an American sitcom * ''Karen'' (film), a 2021 American crime thriller Other uses * Karen (orangutan), the first to have open heart surgery * AS-10 Karen or Kh-25, a Soviet air-to-ground missile * Kiwi Advanced Research and Education Network * Tropical Storm Karen (other) See also * Karren (name) * Karyn (given name) * Keren, Eritrea a city * Caren (disam ...
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Patrick Winston
Patrick Henry Winston (February 5, 1943 – July 19, 2019) was an American computer scientist and professor at the Massachusetts Institute of Technology. Winston was director of the MIT Artificial Intelligence Laboratory from 1972 to 1997, succeeding Marvin Minsky, who left to help found the MIT Media Lab. Winston was succeeded as director by Rodney Brooks. Winston received his undergraduate degree from MIT in 1965, where he was a member of Phi Delta Theta fraternity, and went on to complete his Masters and PhD there as well, finalizing his PhD in 1970. His research interests included machine learning and human intelligence. Winston was known within the MIT community for his excellent teaching and strong commitment to supporting MIT undergraduate culture. At MIT, Winston taught 6.034: Artificial Intelligence and 6.803/6.833: Human Intelligence Enterprise. Winston's ''How to Speak'' talk was an MIT tradition for over 40 years. "Offered every January, the talk is intended to i ...
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Internist-I
{{Short description, Computer-assisted diagnostic software tool INTERNIST-I was a broad-based computer-assisted diagnostic tool developed in the early 1970s at the University of Pittsburgh as an educational experiment. The system was designed to capture the expertise of just one man, Jack D. Myers, MD, chairman of internal medicine in the University of Pittsburgh School of Medicine. The Division of Research Resources and the National Library of Medicine funded INTERNIST-I. Other major collaborators on the project included Randolph A. Miller and Harry E. Pople. Development INTERNIST-I is the successor of the DIALOG system. For ten years, INTERNIST-I was the centerpiece of a Pittsburgh course entitled “The Logic of Problem-Solving in Clinical Diagnosis.” In consultation with faculty experts, much responsibility for data entry and updating of the system fell to the fourth-year medical students enrolled in the course. These students encoded the findings of standard clinicopatholog ...
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Pamela McCorduck
Pamela Ann McCorduck (October 27, 1940 – October 18, 2021) was a British-born American author of books about the history and philosophical significance of artificial intelligence, the future of engineering, and the role of women and technology. She also wrote three novels. She contributed to '' Omni'', ''The New York Times'', ''Daedalus'', and the ''Michigan Quarterly Review'', and was a contributing editor of ''Wired''. She was a former vice president of the PEN American Center. She was married to computer scientist and academic Joseph F. Traub. Early life McCorduck was born on October 27, 1940, in Liverpool, United Kingdom, to Hilda (née Bond) and William J. "Jack" McCorduck. The city was being bombed by the German Luftwaffe at the time of her birth. Her mother was a beautician and teacher, while her father owned beauty colleges, including the one where her mother taught. She was the eldest of three siblings, with the younger two being twins. She moved to Stamford, Conne ...
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Edward A
Edward is an English given name. It is derived from the Anglo-Saxon name ''Ēadweard'', composed of the elements '' ēad'' "wealth, fortune; prosperous" and '' weard'' "guardian, protector”. History The name Edward was very popular in Anglo-Saxon England, but the rule of the Norman and Plantagenet dynasties had effectively ended its use amongst the upper classes. The popularity of the name was revived when Henry III named his firstborn son, the future Edward I, as part of his efforts to promote a cult around Edward the Confessor, for whom Henry had a deep admiration. Variant forms The name has been adopted in the Iberian peninsula since the 15th century, due to Edward, King of Portugal, whose mother was English. The Spanish/Portuguese forms of the name are Eduardo and Duarte. Other variant forms include French Édouard, Italian Edoardo and Odoardo, German, Dutch, Czech and Romanian Eduard and Scandinavian Edvard. Short forms include Ed, Eddy, Eddie, Ted, Teddy and ...
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Inference Engine
In the field of artificial intelligence, an inference engine is a component of the system that applies logical rules to the knowledge base to deduce new information. The first inference engines were components of expert systems. The typical expert system consisted of a knowledge base and an inference engine. The knowledge base stored facts about the world. The inference engine applies logical rules to the knowledge base and deduced new knowledge. This process would iterate as each new fact in the knowledge base could trigger additional rules in the inference engine. Inference engines work primarily in one of two modes either special rule or facts: forward chaining and backward chaining. Forward chaining starts with the known facts and asserts new facts. Backward chaining starts with goals, and works backward to determine what facts must be asserted so that the goals can be achieved. Architecture The logic that an inference engine uses is typically represented as IF-THEN rules. The ...
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Knowledge Base
A knowledge base (KB) is a technology used to store complex structured and unstructured information used by a computer system. The initial use of the term was in connection with expert systems, which were the first knowledge-based systems. Original usage of the term The original use of the term knowledge base was to describe one of the two sub-systems of an expert system. A knowledge-based system consists of a knowledge-base representing facts about the world and ways of reasoning about those facts to deduce new facts or highlight inconsistencies. Properties The term "knowledge-base" was coined to distinguish this form of knowledge store from the more common and widely used term '' database''. During the 1970s, virtually all large management information systems stored their data in some type of hierarchical or relational database. At this point in the history of information technology, the distinction between a database and a knowledge-base was clear and unambiguou ...
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Bacteremia
Bloodstream infections (BSIs), which include bacteremias when the infections are bacterial and fungemias when the infections are fungal, are infections present in the blood. Blood is normally a sterile environment, so the detection of microbes in the blood (most commonly accomplished by blood cultures) is always abnormal. A bloodstream infection is different from sepsis, which is the host response to bacteria. Bacteria can enter the bloodstream as a severe complication of infections (like pneumonia or meningitis), during surgery (especially when involving mucous membranes such as the gastrointestinal tract), or due to catheters and other foreign bodies entering the arteries or veins (including during intravenous drug abuse). Transient bacteremia can result after dental procedures or brushing of teeth. Bacteremia can have several important health consequences. The immune response to the bacteria can cause sepsis and septic shock, which has a high mortality rate. Bacter ...
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Bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, Hot spring, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria are vital in many stages of the nutrient cycle by recycling nutrients such as the nitrogen fixation, fixation of nitrogen from the Earth's atmosphere, atmosphere. The nutrient cycle includes the decomposition of cadaver, dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulp ...
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