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Phenomics
Phenomics is the systematic study of traits that make up an organisms phenotype, which changes over time, due to development and aging or through metamorphosis such as when a caterpillar changes into a butterfly. The term "phenomics" was coined by scientist Steven A. Garan, working at UC Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a public land-grant research university in Berkeley, California, United States. Founded in 1868 and named after the Anglo-Irish philosopher George Berkele ... and LBNL. As such, it is a transdisciplinary area of research that involves biology, data sciences, engineering and other fields. Phenomics is concerned with the measurement of the phenotype where a phenome is a set of Phenotypic trait, traits (physical and biochemical traits) that can be produced by a given organism over the course of development and in response to genetic mutation and environmental influences. An organism's phenotype c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenotype
In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology (physical form and structure), its developmental processes, its biochemical and physiological properties, and its behavior. An organism's phenotype results from two basic factors: the expression of an organism's genetic code (its genotype) and the influence of environmental factors. Both factors may interact, further affecting the phenotype. When two or more clearly different phenotypes exist in the same population of a species, the species is called polymorphic. A well-documented example of polymorphism is Labrador Retriever coloring; while the coat color depends on many genes, it is clearly seen in the environment as yellow, black, and brown. Richard Dawkins in 1978 and again in his 1982 book '' The Extended Phenotype'' suggested that one can regard bird nests and other built structures such as caddisfly larva cases and beaver dams ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenome
In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology (physical form and structure), its developmental processes, its biochemical and physiological properties, and its behavior. An organism's phenotype results from two basic factors: the expression of an organism's genetic code (its genotype) and the influence of environmental factors. Both factors may interact, further affecting the phenotype. When two or more clearly different phenotypes exist in the same population of a species, the species is called polymorphic. A well-documented example of polymorphism is Labrador Retriever coloring; while the coat color depends on many genes, it is clearly seen in the environment as yellow, black, and brown. Richard Dawkins in 1978 and again in his 1982 book ''The Extended Phenotype'' suggested that one can regard bird nests and other built structures such as caddisfly larva cases and beaver dams as "e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenotype Microarray
The phenotype microarray approach is a technology for high-throughput phenotyping of cells. A phenotype microarray system enables one to monitor simultaneously the phenotypic reaction of cells to environmental challenges or exogenous compounds in a high-throughput manner. The phenotypic reactions are recorded as either end-point measurements or respiration kinetics similar to growth curves. Usages High-throughput phenotypic testing is increasingly important for exploring the biology of bacteria, fungi, yeasts, and animal cell lines such as human cancer cells. Just as DNA microarrays and proteomic technologies have made it possible to assay the expression level of thousands of genes or proteins all a once, phenotype microarrays (PMs) make it possible to quantitatively measure thousands of cellular phenotypes simultaneously. The approach also offers potential for testing gene function and improving genome annotation. In contrast to many of the hitherto available molecular high- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PhenomicDB
PhenomicDB is a free phenotype oriented database. It contains data for some of the main model organisms such as ''Homo sapiens, Mus musculus, Drosophila melanogaster'', and others. PhenomicDB merges and structures phenotypic data from various public sources: WormBase WormBase is an online biological database about the biology and genome of the nematode model organism ''Caenorhabditis elegans'' and contains information about other related nematodes. WormBase is used by the ''C. elegans'' research community bo ..., FlyBase, NCBI Gene, MGI and ZFIN using clustering algorithms. The website is now offline. References Further reading * * * * * External links * Phenomics Biological databases {{bioinformatics-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agricultural Research
Agricultural science (or agriscience for short) is a broad multidisciplinary field of biology that encompasses the parts of exact, natural, economic and social sciences that are used in the practice and understanding of agriculture. Professionals of the agricultural science are called agricultural scientists or agriculturists. History In the 18th century, Johann Friedrich Mayer (agriculturist), Johann Friedrich Mayer conducted experiments on the use of gypsum (hydrated calcium sulfate) as a fertilizer.John Armstrong, Jesse Buel. ''A Treatise on Agriculture, The Present Condition of the Art Abroad and at Home, and the Theory and Practice of Husbandry. To which is Added, a Dissertation on the Kitchen and Garden.'' 1840. p. 45. In 1843, John Lawes, John Bennet Lawes and Joseph Henry Gilbert began a set of long-term field experiments at Rothamsted Research Station, Rothamsted Research in England, some of which are still running as of 2018. In the United States, a scientific revo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Phenotype Ontology
The Human Phenotype Ontology (HPO) is a formal ontology of human phenotypes. Developed as part of the Monarch Initiative in collaboration with members of the Open Biomedical Ontologies Foundry, HPO currently contains over 13,000 terms and over 156,000 annotations to hereditary diseases. Data from Online Mendelian Inheritance in Man and medical literature were used to generate the terms currently in the HPO. The ontology contains over 50,000 annotations between phenotypes and hereditary disease. Motivation The Human Phenotype Ontology (HPO) was created in 2008 at the Charité to serve as a standardized vocabulary of phenotypic abnormalities that have been seen in human disease. Applications for the data in the ontology include clinical diagnostics, mapping between phenotypes of model organisms, and as a standard vocabulary for clinical databases. Clinical annotations within the HPO are sought from the medical and genetics community to improve the ontology. See also * Disease Ont ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Nebraska-Lincoln
A university () is an institution of tertiary education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase , which roughly means "community of teachers and scholars". Universities typically offer both undergraduate and postgraduate programs. The first universities in Europe were established by Catholic monks. The University of Bologna (), Italy, which was founded in 1088, is the first university in the sense of: *being a high degree-awarding institute. *using the word (which was coined at its foundation). *having independence from the ecclesiastic schools and issuing secular as well as non-secular degrees (with teaching conducted by both clergy and non-clergy): grammar, rhetoric, logic, theology, canon law and notarial law.Hunt Janin: "The university in medieval life, 1179–1499", McFarland, 2008, , p. 55f.de Ridder-Symoens, Hilde''A History of the University in Europe: Volume 1, Universities in the M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Donald Danforth Plant Science Center
The Donald Danforth Plant Science Center is an independent, not-for-profit research institute dedicated to plant science located in the Creve Coeur community of Saint Louis County, Missouri, United States. It was founded in 1998 by William Henry Danforth, chancellor emeritus of Washington University in St. Louis and named after his father, and established through a $60 million gift from the Danforth Foundation, a $50 million gift from the Monsanto Fund, the donation of 40 acres of land from Monsanto, and $25 million in tax credits from the State of Missouri. The Center has a $30 million annual operating budget, a $300 million endowment, and 242 employees, including 30 principal investigators. It is home to the Enterprise Rent-A-Car Institute for Renewable Fuels and the International Institute for Crop Improvement. The Danforth Center Core Facilities include bioinformatics, integrated microscopy, phenotyping, plant growth, proteomics and mass spectrometry, and tissue culture ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Iowa State University
Iowa State University of Science and Technology (Iowa State University, Iowa State, or ISU) is a Public university, public land-grant university, land-grant research university in Ames, Iowa, United States. Founded in 1858 as the Iowa Agricultural College and Model Farm, Iowa State became one of the nation's first designated land-grant institutions when the Iowa Legislature accepted the provisions of the 1862 Morrill Land-Grant Colleges Act, Morrill Act on September 11, 1862. On July 4, 1959, the college was officially renamed Iowa State University of Science and Technology. Iowa State is the second largest university in Iowa by total enrollment. The university's academic offerings are administered through eight colleges, including the Iowa State University College of Agriculture and Life Sciences, College of Agriculture and Life Sciences, the Iowa State University College of Veterinary Medicine, College of Veterinary Medicine, the Iowa State University College of Engineering, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The University Of Arizona
The University of Arizona (Arizona, U of A, UArizona, or UA) is a public land-grant research university in Tucson, Arizona, United States. Founded in 1885 by the 13th Arizona Territorial Legislature, it was the first university established in the Arizona Territory. The University of Arizona is one of three universities governed by the Arizona Board of Regents (the University of Arizona, Arizona State University, and Northern Arizona University). , the university enrolled 53,187 students in 22 separate colleges/schools, including the Eller College of Management, the Wyant College of Optical Sciences, the College of Medicine – Phoenix, the College of Medicine – Tucson, and the James E. Rogers College of Law. The university is classified among "R1: Doctoral Universities – Very high research activity". UA also is a member of the Association of American Universities. The University of Arizona is affiliated with two academic medical centers, Banner – University Medical Ce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phylogenetics
In biology, phylogenetics () is the study of the evolutionary history of life using observable characteristics of organisms (or genes), which is known as phylogenetic inference. It infers the relationship among organisms based on empirical data and observed heritable traits of DNA sequences, protein amino acid sequences, and morphology. The results are a phylogenetic tree—a diagram depicting the hypothetical relationships among the organisms, reflecting their inferred evolutionary history. The tips of a phylogenetic tree represent the observed entities, which can be living taxa or fossils. A phylogenetic diagram can be rooted or unrooted. A rooted tree diagram indicates the hypothetical common ancestor of the taxa represented on the tree. An unrooted tree diagram (a network) makes no assumption about directionality of character state transformation, and does not show the origin or "root" of the taxa in question. In addition to their use for inferring phylogenetic pa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
