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Cortical Cooling
Cortical cooling refers to the cooling methods restricted to the cerebral cortex, where most higher brain processes occur. Neuroscientists generate various studies to help explain many of the complex connections and functions of the brain. Most studies utilize animal models that have varying degrees of comparison to the human brain; for example, small rodents are less comparable than non-human primates. One of the most definitive ways of determining which sections of the brain contribute to certain behavior or function is to deactivate a section of the brain and observe what behavior is altered. Lowering the temperature of the neural tissue has the effect of reducing metabolic activity in the affected region. This metabolic suppression slows down or inhibits neural firing, synaptic transmission, and other cellular processes that rely on energy. Below is a list of current cooling methods, their advantages and limitations, and some studies that have used cooling to elucidate neural func ...
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Cerebral Cortex
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system. It plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The cerebral cortex is part of the brain responsible for cognition. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the cranium. Apart from minimising brain and cranial volume, cortical folding is crucial for ...
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Thermocline
A thermocline (also known as the thermal layer or the metalimnion in lakes) is a distinct layer based on temperature within a large body of fluid (e.g. water, as in an ocean or lake; or air, e.g. an atmosphere) with a high gradient of distinct temperature differences associated with depth. In the ocean, the thermocline divides the upper mixed layer from the calm deep water below. Depending largely on season, latitude, and turbulent mixing by wind, thermoclines may be a semi-permanent feature of the body of water in which they occur, or they may form temporarily in response to phenomena such as the radiative heating/cooling of surface water during the day/night. Factors that affect the depth and thickness of a thermocline include seasonal weather variations, latitude, and local environmental conditions, such as tides and currents. Oceans Most of the heat energy of the sunlight that strikes the Earth is absorbed in the first few centimeters at the ocean's surface, which heats ...
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Depolarization
In biology, depolarization or hypopolarization is a change within a cell, during which the cell undergoes a shift in electric charge distribution, resulting in less negative charge inside the cell compared to the outside. Depolarization is essential to the function of many cells, communication between cells, and the overall physiology of an organism. Most cells in higher organisms maintain an internal environment that is negatively charged relative to the cell's exterior. This difference in charge is called the cell's membrane potential. In the process of depolarization, the negative internal charge of the cell temporarily becomes more positive (less negative). This shift from a negative to a more positive membrane potential occurs during several processes, including an action potential. During an action potential, the depolarization is so large that the potential difference across the cell membrane briefly reverses polarity, with the inside of the cell becoming positively charge ...
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Scientific Control
A scientific control is an experiment or observation Observation is the active acquisition of information from a primary source. In living beings, observation employs the senses. In science, observation can also involve the perception and recording of data via the use of scientific instruments. The ... designed to minimize the effects of variables other than the independent variable (i.e. confounding variables). This increases the reliability of the results, often through a comparison between control measurements and the other measurements. Scientific controls are a part of the scientific method. Controlled experiments Controls eliminate alternate explanations of experimental results, especially experimental errors and experimenter bias. Many controls are specific to the type of experiment being performed, as in the molecular markers used in SDS-PAGE experiments, and may simply have the purpose of ensuring that the equipment is working properly. The selection and use of pr ...
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Brodmann Area 7
Brodmann area 7 is one of Brodmann's cytologically defined regions of the brain corresponding to precuneus and superior parietal lobule (SPL). It is involved in locating objects in space. It serves as a point of convergence between vision and proprioception to determine where objects are in relation to parts of the body. In humans Brodmann area 7 is part of the parietal cortex in the human brain. Situated posterior to the primary somatosensory cortex (Brodmann areas 3, 1 and 2), and superior to the occipital lobe, this region is believed to play a role in visuo-motor coordination (e.g., in reaching to grasp an object). In addition, area 7 along with area 5 has been linked to a wide variety of high-level processing tasks, including activation in association with language use. This function in language has been theorized to stem from how these two regions play a vital role in generating conscious constructs of objects in the world. Brodmann area 7 spans both the medial and later ...
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Visual Cortex
The visual cortex of the brain is the area of the cerebral cortex that processes visual information. It is located in the occipital lobe. Sensory input originating from the eyes travels through the lateral geniculate nucleus in the thalamus and then reaches the visual cortex. The area of the visual cortex that receives the sensory input from the lateral geniculate nucleus is the primary visual cortex, also known as visual area 1 ( V1), Brodmann area 17, or the striate cortex. The extrastriate areas consist of visual areas 2, 3, 4, and 5 (also known as V2, V3, V4, and V5, or Brodmann area 18 and all Brodmann area 19). Both hemispheres of the brain include a visual cortex; the visual cortex in the left hemisphere receives signals from the right visual field, and the visual cortex in the right hemisphere receives signals from the left visual field. Introduction The primary visual cortex (V1) is located in and around the calcarine fissure in the occipital lobe. Each hemisphe ...
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Contralateral
Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position provides a definition of what is at the front ("anterior"), behind ("posterior") and so on. As part of defining and describing terms, the body is described through the use of anatomical planes and anatomical axes. The meaning of terms that are used can change depending on whether an organism is bipedal or quadrupedal. Additionally, for some animals such as invertebrates, some terms may not have any meaning at all; for example, an animal that is radially symmetrical will have no anterior surface, but can still have a description that a part is close to the middle ("proximal") or further from the middle ("distal"). International organisations have determined vocabularies that are often used as standard vocabularies for subdisciplines of ana ...
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Primary Auditory Cortex
The auditory cortex is the part of the temporal lobe that processes auditory information in humans and many other vertebrates. It is a part of the auditory system, performing basic and higher functions in hearing, such as possible relations to language switching.Cf. Pickles, James O. (2012). ''An Introduction to the Physiology of Hearing'' (4th ed.). Bingley, UK: Emerald Group Publishing Limited, p. 238. It is located bilaterally, roughly at the upper sides of the temporal lobes – in humans, curving down and onto the medial surface, on the superior temporal plane, within the lateral sulcus and comprising parts of the transverse temporal gyri, and the superior temporal gyrus, including the planum polare and planum temporale (roughly Brodmann areas 41 and 42, and partially 22). The auditory cortex takes part in the spectrotemporal, meaning involving time and frequency, analysis of the inputs passed on from the ear. The cortex then filters and passes on the information to ...
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Bilateral
Bilateral may refer to any concept including two sides, in particular: *Bilateria, bilateral animals *Bilateralism, the political and cultural relations between two states *Bilateral, occurring on both sides of an organism ( Anatomical terms of location § Medial and lateral) * Bilateral symmetry, symmetry between two sides of an organism *Bilateral filter, an image processing algorithm * Bilateral amplifier, a type of amplifier * ''Bilateral'' (album), an album by the band ''Leprous'' *Bilateral school, see Partially selective school (England) In England, a partially selective school is one of a few dozen state-funded secondary schools that select a proportion of their intake by ability or aptitude, permitted as a continuation of arrangements that existed prior to 1997. Though treated ...
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Sound Localization
Sound localization is a listener's ability to identify the location or origin of a detected sound in direction and distance. The sound localization mechanisms of the mammalian auditory system have been extensively studied. The auditory system uses several cues for sound source localization, including time difference and level difference (or intensity difference) between the ears, and spectral information. These cues are also used by other animals, such as birds and reptiles, but there may be differences in usage, and there are also localization cues which are absent in the human auditory system, such as the effects of ear movements. Animals with the ability to localize sound have a clear evolutionary advantage. How sound reaches the brain Sound is the perceptual result of mechanical vibrations traveling through a medium such as air or water. Through the mechanisms of compression and rarefaction, sound waves travel through the air, bounce off the pinna and concha of the exter ...
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Edema
Edema, also spelled oedema, and also known as fluid retention, dropsy, hydropsy and swelling, is the build-up of fluid in the body's tissue. Most commonly, the legs or arms are affected. Symptoms may include skin which feels tight, the area may feel heavy, and joint stiffness. Other symptoms depend on the underlying cause. Causes may include venous insufficiency, heart failure, kidney problems, low protein levels, liver problems, deep vein thrombosis, infections, angioedema, certain medications, and lymphedema. It may also occur after prolonged sitting or standing and during menstruation or pregnancy. The condition is more concerning if it starts suddenly, or pain or shortness of breath is present. Treatment depends on the underlying cause. If the underlying mechanism involves sodium retention, decreased salt intake and a diuretic may be used. Elevating the legs and support stockings may be useful for edema of the legs. Older people are more commonly affected. The wo ...
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