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Buck Institute For Age Research
The Buck Institute for Research on Aging is an independent biomedical research institute that researches aging and age-related disease. The mission of the Buck Institute is to extend the healthy years of life. The Buck Institute is one of nine centers for aging research of the Glenn Foundation for Medical Research. The institute, a nonprofit organization located in Novato, California, began its research program in 1999, making it the world's first institute founded primarily to study intervention into the aging process. It is named for Marin County philanthropists Leonard and Beryl Hamilton Buck, whose estate funded the endowment that helped establish the institute, and the Buck Trust currently contributes approximately $6 million annually to support the institute's work. The campus of the Buck Institute was designed by architect I. M. Pei. In May 2007, the institute established a cooperative agreement with the University of California's Davis and Merced campuses to coordinate st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Buck Logo Tagline Period
Buck may refer to: Common meanings * A colloquialism for a dollar or similar currency * An adult male in some animal species - see List of animal names * Derby shoes, nicknamed "bucks" for the common use of buckskin in their making People *Buck (nickname) *Buck Pierce (born 1981), Canadian football quarterback *Buck (surname), a list of people *Buck 65, stage name of Canadian hip hop artist Richard Terfry *Buck Angel, stage name of American trans man, adult film producer and performer Jake Miller (born 1972) *Buck Dharma, stage name of American guitarist Donald Roeser (born 1947) *Buck Ellison (born 1987), American artist *Buck Henry, stage name of American actor, writer, and director Henry Zuckerman (1930–2020) *Buck Jones, stage name of American film actor Charles Gebhart (1891–1942) *Buck Owens, stage name of American singer and guitarist Alvis Owens Jr. (1929–2006) *Young Buck, stage name of American rapper David Darnell Brown (born 1981) *David Paul Grove (born 1958), C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Buck Institute For Research On Aging, Novato, California -- Campus, As Seen From Hwy 101
Buck may refer to: Common meanings * A colloquialism for a dollar or similar currency * An adult male in some animal species - see List of animal names * Derby shoes, nicknamed "bucks" for the common use of buckskin in their making People *Buck (nickname) *Buck Pierce (born 1981), Canadian football quarterback *Buck (surname), a list of people *Buck 65, stage name of Canadian hip hop artist Richard Terfry *Buck Angel, stage name of American trans man, adult film producer and performer Jake Miller (born 1972) *Buck Dharma, stage name of American guitarist Donald Roeser (born 1947) *Buck Ellison (born 1987), American artist *Buck Henry, stage name of American actor, writer, and director Henry Zuckerman (1930–2020) *Buck Jones, stage name of American film actor Charles Gebhart (1891–1942) *Buck Owens, stage name of American singer and guitarist Alvis Owens Jr. (1929–2006) *Young Buck, stage name of American rapper David Darnell Brown (born 1981) *David Paul Grove (born 1958), C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
San Francisco Chronicle
The ''San Francisco Chronicle'' is a newspaper serving primarily the San Francisco Bay Area of Northern California. It was founded in 1865 as ''The Daily Dramatic Chronicle'' by teenage brothers Charles de Young and Michael H. de Young. The paper is owned by the Hearst Corporation, which bought it from the de Young family in 2000. It is the only major daily paper covering the city and county of San Francisco. The paper benefited from the growth of San Francisco and had the largest newspaper circulation on the West Coast of the United States by 1880. Like other newspapers, it experienced a rapid fall in circulation in the early 21st century and was ranked 18th nationally by circulation in the first quarter of 2021. In 1994, the newspaper launched the SFGATE website, with a soft launch in March and official launch November 3, 1994, including both content from the newspaper and other sources. "The Gate" as it was known at launch was the first large market newspaper website in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the typical life expectancy following diagnosis is three to nine years. The cause of Alzheimer's disease is poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an allele of APOE. Other risk factors include a history of head injury, clinical depression, and high blood pre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marin County, California
Marin County is a county located in the northwestern part of the San Francisco Bay Area of the U.S. state of California. As of the 2020 census, the population was 262,231. Its county seat and largest city is San Rafael. Marin County is across the Golden Gate Bridge from San Francisco, and is included in the San Francisco–Oakland–Berkeley, CA Metropolitan Statistical Area. Marin County's natural sites include the Muir Woods redwood forest, the Marin Headlands, Stinson Beach, the Point Reyes National Seashore, and Mount Tamalpais. As of 2019, Marin County had the sixth highest income per capita of all U.S. counties, at $141,735. The county is governed by the Marin County Board of Supervisors. The Marin County Civic Center was designed by Frank Lloyd Wright and draws thousands of visitors a year to guided tours of its arch and atrium design. In 1994, a new county jail facility was embedded into the hillside nearby. The United States' oldest cross country running event ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mount Tamalpais
Mount Tamalpais (; ; Miwok: ''Támal Pájiṣ''), known locally as Mount Tam, is a peak in Marin County, California, United States, often considered symbolic of Marin County. Much of Mount Tamalpais is protected within public lands such as Mount Tamalpais State Park, the Marin Municipal Water District watershed, and National Park Service land, such as Muir Woods. Toponym The name ''Tamalpais'' was first recorded in 1845. It comes from the Coast Miwok name for this mountain, '' támal pájiṣ'', meaning "west hill". Various different folk etymologies also exist, but they are unsubstantiated. One holds that it comes from the Spanish ''Tamal país'', meaning "Tamal country," ''Tamal'' being the name that the Spanish missionaries gave to the Coast Miwok people. Another holds that the name is the Coast Miwok word for "sleeping maiden" and is taken from a " Legend of the Sleeping Maiden" Supposedly, the legend is that the mountain's contour reflects the reclining profile of a youn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sirolimus
Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumor ( PEComa). It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It is a mechanistic target of rapamycin kinase (mTOR) inhibitor that inhibits activation of T cells and B cells by reducing their sensitivity to interleukin-2 (IL-2). It is produced by the bacterium ''Streptomyces hygroscopicus'' and was isolated for the first time in 1972, from samples of ''Streptomyces hygroscopicus'' found on Easter Island. The compound was originally named rapamycin after the native name of the island, Rapa Nui. Sirolimus was initially developed as an antifungal agent. However, this use was abandoned when it was discovered to have potent im ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Startup
A startup or start-up is a company or project undertaken by an entrepreneur to seek, develop, and validate a scalable business model. While entrepreneurship refers to all new businesses, including self-employment and businesses that never intend to become registered, startups refer to new businesses that intend to grow large beyond the solo founder. At the beginning, startups face high uncertainty and have high rates of failure, but a minority of them do go on to be successful and influential.Erin Griffith (2014)Why startups fail, according to their founders Fortune.com, 25 September 2014; accessed 27 October 2017 Actions Startups typically begin by a founder (solo-founder) or co-founders who have a way to solve a problem. The founder of a startup will begin market validation by problem interview, solution interview, and building a minimum viable product (MVP), i.e. a prototype, to develop and validate their business models. The startup process can take a long period of time (by so ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stem-cell Line
A stem cell line is a group of stem cells that is cultured in vitro and can be propagated indefinitely. Stem cell lines are derived from either animal or human tissues and come from one of three sources: embryonic stem cells, adult stem cells, or induced stem cells. They are commonly used in research and regenerative medicine. Properties By definition, stem cells possess two properties: (1) they can self-renew, which means that they can Cell division, divide indefinitely while remaining in an Cellular differentiation, undifferentiated state; and (2) they are pluripotent or Progenitor cell, multipotent, which means that they can differentiate to form specialized cell types. Due to the self-renewal capacity of stem cells, a stem cell line can be cultured ''in vitro'' indefinitely. A stem-cell line is distinctly different from an immortalised cell line, immortalized cell line, such as the HeLa line. While stem cells can propagate indefinitely in culture due to their inherent proper ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Bank
A cell bank is a facility that stores cells of specific genome for the purpose of future use in a product or medicinal needs. They often contain expansive amounts of base cell material that can be utilized for various projects. Cell banks can be used to generate detailed characterizations of cell lines and can also help mitigate cross-contamination of a cell line. Utilizing cell banks also reduces the cost of cell culture processes, providing a cost-efficient alternative to keeping cells in culture constantly. Cell banks are commonly used within fields including stem cell research and pharmaceuticals, with cryopreservation being the traditional method of keeping cellular material intact. Cell banks also effectively reduce the frequency of a cell sample diversifying from natural cell divisions over time. Storage Before putting the donated cell lines into storage, they are first proliferated and multiplied into a large number of identical cells before being stored in a number of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research ins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peer-reviewed
Peer review is the evaluation of work by one or more people with similar competencies as the producers of the work ( peers). It functions as a form of self-regulation by qualified members of a profession within the relevant field. Peer review methods are used to maintain quality standards, improve performance, and provide credibility. In academia, scholarly peer review is often used to determine an academic paper's suitability for publication. Peer review can be categorized by the type of activity and by the field or profession in which the activity occurs, e.g., medical peer review. It can also be used as a teaching tool to help students improve writing assignments. Henry Oldenburg (1619–1677) was a German-born British philosopher who is seen as the 'father' of modern scientific peer review. Professional Professional peer review focuses on the performance of professionals, with a view to improving quality, upholding standards, or providing certification. In academia, p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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