British Pharmacopoeia
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British Pharmacopoeia
The ''British Pharmacopoeia'' (''BP'') is the national pharmacopoeia of the United Kingdom. It is an annually published collection of quality standards for medicinal substances in the UK, which is used by individuals and organisations involved in pharmaceutical research, development, manufacture and testing. Pharmacopoeial standards are publicly available and legally enforceable standards of quality for medicinal products and their constituents. The ''British Pharmacopoeia'' is an important statutory component in the control of medicines, which complements and assists the licensing and inspection processes of the UK's Medicines and Healthcare products Regulatory Agency (MHRA). Together with the ''British National Formulary'' (BNF), the ''British Pharmacopoeia'' defines the UK's pharmaceutical standards. Pharmacopoeial standards are compliance requirements; that is, they provide the means for an independent judgement as to the overall quality of an article, and apply throug ...
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London
London is the Capital city, capital and List of urban areas in the United Kingdom, largest city of both England and the United Kingdom, with a population of in . London metropolitan area, Its wider metropolitan area is the largest in Western Europe, with a population of 14.9 million. London stands on the River Thames in southeast England, at the head of a tidal estuary down to the North Sea, and has been a major settlement for nearly 2,000 years. Its ancient core and financial centre, the City of London, was founded by the Roman Empire, Romans as Londinium and has retained its medieval boundaries. The City of Westminster, to the west of the City of London, has been the centuries-long host of Government of the United Kingdom, the national government and Parliament of the United Kingdom, parliament. London grew rapidly 19th-century London, in the 19th century, becoming the world's List of largest cities throughout history, largest city at the time. Since the 19th cen ...
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European Pharmacopoeia
The ''European Pharmacopoeia'' (''Pharmacopoeia Europaea'', ''Ph. Eur.'') is a major regional pharmacopoeia which provides common quality standards throughout the pharmaceutical industry in Europe to control the quality of Pharmaceutical drug, medicines, and the substances used to Pharmaceutical manufacturing, manufacture them. It is a published collection of monographs which describe both the individual and general quality standards for ingredients, dosage forms, and methods of Pharmaceutical engineering, analysis for medicines. These standards apply to medicines for both Medicine, human and Veterinary medicine, veterinary use. Legal basis The ''European Pharmacopoeia'' has a Contract, legally binding character. It is used as an official reference to serve public health, and is part of the regulatory requirements for obtaining a Marketing Authorisation (MA) for a medicinal (human or veterinary) product. The quality standards of the European Pharmacopoeia apply throughout the ...
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Royal Pharmaceutical Society
The Royal Pharmaceutical Society (RPharmS or RPS) is the body responsible for the leadership and support of the pharmacy profession (pharmacists) within England, Scotland, and Wales. It was created along with the General Pharmaceutical Council (GPhC) in September 2010 when the previous Royal Pharmaceutical Society of Great Britain was split so that representative and regulatory functions of the pharmacy profession could be separated. Membership in the society is not a prerequisite for engaging in practice as a pharmacist within the United Kingdom. Its predecessor the Pharmaceutical Society of Great Britain was founded on 15 April 1841. History The Royal Pharmaceutical Society was founded on 15 April 1841 as the Pharmaceutical Society of Great Britain, and headquartered at 17 Bloomsbury Square, London. Among its founding members were Jacob Bell and William Allen. The Northern British (Scottish) branch began the same year with nine founders including William Flockhart and Joh ...
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Anesthesia
Anesthesia (American English) or anaesthesia (British English) is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prevention of pain), paralysis (muscle relaxation), amnesia (loss of memory), and unconsciousness. An individual under the effects of anesthetic drugs is referred to as being anesthetized. Anesthesia enables the painless performance of procedures that would otherwise require physical restraint in a non-anesthetized individual, or would otherwise be technically unfeasible. Three broad categories of anesthesia exist: * ''General anesthesia'' suppresses central nervous system activity and results in unconsciousness and total lack of Sensation (psychology), sensation, using either injected or inhaled drugs. * ''Sedation'' suppresses the central nervous system to a lesser degree, inhibiting both anxiolysis, anxiety and creation of long-term memory, ...
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James Young Simpson
Sir James Young Simpson, 1st Baronet (7 June 1811 – 6 May 1870) was a Scottish obstetrician and a significant figure in the history of medicine. He was the first physician to demonstrate the anaesthetic properties of chloroform in humans and helped to popularize its use in medicine. Simpson's intellectual interests ranged from archaeology to an almost taboo subject at the time: hermaphroditism. He was an early advocate of the use of midwives in the hospital environment. Many prominent women also consulted him for their gynaecological problems. Simpson wrote ''Homœopathy, its Tenets and Tendencies,'' refuting the ideas put forward by Hahnemann. His services as an early founder of gynaecology and proponent of hospital reform were rewarded with a knighthood, and by 1847 he had been appointed as physician to the Queen in Scotland. Queen Victoria also used anaesthesia for her childbirth, resulting in a significant increase of popularity in anaesthesia. Simpson was a close fr ...
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William Flockhart
William Flockhart, L.R.C.S.E. (1808 – 1871) was a Scottish chemist, a pharmacist who provided chloroform to Doctor (later Sir) James Young Simpson for his anaesthesia experiment at 52 Queen Street, Edinburgh on 4 November 1847. This was the first use of this chemical on humans when Simpson tried it on himself and a few friends, and then used it for pain relief in obstetrics, and surgery. This changed medical practice for over a century, according to the British Medical Journal. Career Flockhart had joined John Duncan (also from Kinrosshire, who was 28 years his senior), as a partner in 1833, having started as an apprentice surgeon-apothecary and qualifying as a licenciate of the Royal College of Surgeons Edinburgh in 1830, when he was 22 years old. He did not practise as a surgeon, but with Duncan, worked closely with other doctors in Edinburgh on experimental drugs, which they then refined to improve in purity, following the medical experiments' results. They were both amo ...
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Neo-Latin
Neo-LatinSidwell, Keith ''Classical Latin-Medieval Latin-Neo Latin'' in ; others, throughout. (also known as New Latin and Modern Latin) is the style of written Latin used in original literary, scholarly, and scientific works, first in Italy during the Italian Renaissance of the fourteenth and fifteenth centuries, and then across northern Europe after about 1500, as a key feature of the humanist movement. Through comparison with Classical Latin, Latin of the Classical period, scholars from Petrarch onwards promoted a standard of Latin closer to that of the ancient Romans, especially in grammar, style, and spelling. The term ''Neo-Latin'' was however coined much later, probably in Germany in the late eighteenth century, as ''Neulatein'', spreading to French and other languages in the nineteenth century. Medieval Latin had diverged quite substantially from the classical standard and saw notable regional variation and influence from vernacular languages. Neo-Latin attempts to retur ...
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Approved Drug
An approved drug is a Medicine, medicinal preparation that has been validated for a therapeutic use by a Regulation of therapeutic goods, ruling authority of a government. This process is usually specific by country, unless specified otherwise. Process by country United States In the United States, the Food and Drug Administration, FDA approves medication, drugs. Before a drug can be prescribed, it must undergo the FDA's approval process. While a drug can feasibly be used off-label (for non-approved indications), it still is required to be approved for a specific disease or medical condition. Drug companies seeking to sell a drug in the United States must first test it. The company then sends the Food and Drug Administration's Center for Drug Evaluation and Research (CDER) evidence from these tests to prove the drug is safe and effective for its intended use. A fee is required to make such FDA submission. For financial year 2020, this fee was: for an application requiring clini ...
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Apothecary
''Apothecary'' () is an Early Modern English, archaic English term for a medicine, medical professional who formulates and dispenses ''materia medica'' (medicine) to physicians, surgeons and patients. The modern terms ''pharmacist'' and, in British English, ''chemist'' have taken over this role. In some languages and regions, terms similar to "apothecary" have survived and denote modern pharmacies or pharmacists. Apothecaries' investigation of Herbal medicine, herbal and chemical ingredients was a precursor to the modern sciences of chemistry and pharmacology. In addition to dispensing herbs and medicine, apothecaries offered general medical advice and a range of services that are now performed by other specialist practitioners, such as surgeons and Obstetrics and gynaecology, obstetricians. Apothecary shops sold ingredients and the medicines they prepared wholesale to other medical practitioners, as well as dispensing them to patients. In 17th-century England, they also contro ...
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Royal College Of Physicians
The Royal College of Physicians of London, commonly referred to simply as the Royal College of Physicians (RCP), is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of physicians by examination. Founded by royal charter from King Henry VIII in 1518, as the College of Physicians, the RCP is the oldest medical college in England. The RCP's home in Regent's Park is one of the few post-war buildings to be listed at Grade I. In 2016 it was announced that the RCP was to open new premises in Liverpool at The Spine, a new building in the Liverpool Knowledge Quarter. The Spine opened in May 2021. History The college was incorporated as "the President and College or Commonalty of the Faculty of Physic in London" when it received a royal charter in 1518, affirmed by Act of Parliament in 1523. It is not known when the name "Royal College of Physicians of London" was first assumed or granted. It came into use aft ...
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Henry VIII Of England
Henry VIII (28 June 149128 January 1547) was King of England from 22 April 1509 until his death in 1547. Henry is known for his Wives of Henry VIII, six marriages and his efforts to have his first marriage (to Catherine of Aragon) annulled. His disagreement with Pope Clement VII about such an annulment led Henry to initiate the English Reformation, separating the Church of England from papal authority. He appointed himself Supreme Head of the Church of England and dissolution of the monasteries, dissolved convents and monasteries, for which he was List of people excommunicated by the Catholic Church, excommunicated by the pope. Born in Greenwich, Henry brought radical changes to the Constitution of England, expanding royal power and ushering in the theory of the divine right of kings in opposition to papal supremacy. He frequently used charges of treason and heresy to quell dissent, and those accused were often executed without a formal trial using bills of attainder. He achi ...
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Letters Patent
Letters patent (plurale tantum, plural form for singular and plural) are a type of legal instrument in the form of a published written order issued by a monarch, President (government title), president or other head of state, generally granting an office, right, government-granted monopoly, monopoly, title or status to a person or corporation. Letters patent can be used for the creation of corporations, government offices, to grant city status or heraldry, coats of arms. Letters patent are issued for the appointment of representatives of the Crown, such as governors and governor-general, governors-general of Commonwealth realms, as well as appointing a Royal Commission. In the United Kingdom, they are also issued for the creation of peers of the realm. A particular form of letters patent has evolved into the modern intellectual property patent (referred to as a utility patent or design patent in United States patent law) granting exclusive rights in an invention or design. In ...
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