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Brain On Fire (film)
''Brain on Fire'' is a 2016 biographical drama film directed and written by Irish filmmaker Gerard Barrett. The film is based on Susannah Cahalan's memoir '' Brain on Fire: My Month of Madness'' and stars Chloë Grace Moretz, Jenny Slate, Thomas Mann, Tyler Perry, Carrie-Anne Moss, and Richard Armitage. The film follows a ''New York Post'' writer who begins to experience a mysterious illness. After being evaluated extensively by many doctors, she was diagnosed to be psychotic. She would have been committed to the psychiatric ward in a hospital and probably died of encephalitis, if it were not for the efforts and skills of Syrian-American neurologist Souhel Najjar. He empathized with her case and was able to diagnose and treat her rare illness. Principal photography began on July 13, 2015, in Vancouver, British Columbia. It had its world premiere at the Toronto International Film Festival on September 14, 2016. The film was released on Netflix on June 22, 2018. Plot Twenty-on ...
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Gerard Barrett (director)
Gerard Barrett is an Irish filmmaker. He came to prominence when he won the Rising Star Award at the 10th Irish Film & Television Awards for his debut, '' Pilgrim Hill''. His follow-up '' Glassland'' starred Jack Reynor as a young man who tries to help his mother (Toni Collette). In 2015, Barrett filmed ''Brain on Fire'' based on the book of the same name, starring Chloë Grace Moretz in New York City and Canada. His television mini-series ''Smalltown'' was screened in Ireland in September 2016. In 2017, his movie, ''Limbo'' premiered at the 29th Galway Film Fleadh, and his hour-long drama, ''Honey'', was sold to FX. Barrett attended St Michael's College, Listowel. A graduate of Tralee IT, where he studied Film, TV and Media. He was married on 2 January 2016. Filmography * '' The Valley of Knockanure'' (2009) * '' Pilgrim Hill'' (2013) * '' Glassland'' (2014) * ''Brain on Fire'' (2015) Television * '' Smalltown'' (2016) * ''Limbo'' (2017) Awards * 10th Irish Fil ...
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Irish People
The Irish ( ga, Muintir na hÉireann or ''Na hÉireannaigh'') are an ethnic group and nation native to the island of Ireland, who share a common history and Culture of Ireland, culture. There have been humans in Ireland for about 33,000 years, and it has been continually inhabited for more than 10,000 years (see Prehistoric Ireland). For most of Ireland's recorded history, the Irish have been primarily a Gaels, Gaelic people (see Gaelic Ireland). From the 9th century, small numbers of Vikings settled in Ireland, becoming the Norse-Gaels. Anglo-Normans also Norman invasion of Ireland, conquered parts of Ireland in the 12th century, while Kingdom of England, England's 16th/17th century Tudor conquest of Ireland, conquest and Plantations of Ireland, colonisation of Ireland brought many English people, English and Scottish Lowlands, Lowland Scottish people, Scots to parts of the island, especially the north. Today, Ireland is made up of the Republic of Ireland (officially called Re ...
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Anti-NMDA Receptor Encephalitis
Anti-NMDA receptor encephalitis is a type of brain inflammation caused by antibodies. Early symptoms may include fever, headache, and feeling tired. This is then typically followed by psychosis which presents with false beliefs (delusions) and seeing or hearing things that others do not see or hear (hallucinations). People are also often agitated or confused. Over time seizures, decreased breathing, and blood pressure and heart rate variability typically occur. About half of cases are associated with tumors, most commonly teratomas of the ovaries. Another established trigger is herpesviral encephalitis, while the cause in others cases is unclear. The underlying mechanism is autoimmune with the primary target the GluN1 subunit of the N-methyl D-aspartate receptors (NMDAR) in the brain. Diagnosis is typically based on finding specific antibodies in the cerebral spinal fluid. MRI of the brain is often normal. Misdiagnosis is common. Treatment is typically with immunosuppresi ...
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Navid Negahban
Navid Negahban ( fa, نوید نگهبان; born June 2, 1968) is an Iranian-American actor. He has appeared on '' 24'', ''Homeland'', '' Mistresses'' and as Amahl Farouk / Shadow King in the second and third seasons of FX's ''Legion''. He has also starred as The Sultan in the live-action remake of ''Aladdin''. Early life Negahban was born in Mashhad, Iran. He took a liking to the theater when he was eight years old, while provoking laughter from a large audience by portraying an old man on stage. He left Iran in 1985 when he was 17 for Turkey and then Germany, where he spent eight years. In Germany, he worked for a theater company, and then in 1993 he moved to the United States. He is fluent in English, German and Persian. He also began learning French for his role on ''Legion''. Career He has appeared in ''The Shield'', ''The West Wing'', ''Lost'', and ''CSI: Miami''. He has collaborated twice with Iranian-American actress Necar Zadegan, once in '' 24'', where her on-screen ...
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Schizophrenia
Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdrawal, decreased emotional expression, and apathy. Symptoms typically develop gradually, begin during young adulthood, and in many cases never become resolved. There is no objective diagnostic test; diagnosis is based on observed behavior, a history that includes the person's reported experiences, and reports of others familiar with the person. To be diagnosed with schizophrenia, symptoms and functional impairment need to be present for six months ( DSM-5) or one month (ICD-11). Many people with schizophrenia have other mental disorders, especially substance use disorders, depressive disorders, anxiety disorders, and obsessive–compulsive disorder. About 0.3% to 0.7% of people are diagnosed with schizophrenia during their lifetim ...
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Electroencephalography
Electroencephalography (EEG) is a method to record an electrogram of the spontaneous electrical activity of the brain. The biosignals detected by EEG have been shown to represent the postsynaptic potentials of pyramidal neurons in the neocortex and allocortex. It is typically non-invasive, with the EEG electrodes placed along the scalp (commonly called "scalp EEG") using the International 10-20 system, or variations of it. Electrocorticography, involving surgical placement of electrodes, is sometimes called "intracranial EEG". Clinical interpretation of EEG recordings is most often performed by visual inspection of the tracing or quantitative EEG analysis. Voltage fluctuations measured by the EEG bioamplifier and electrodes allow the evaluation of normal brain activity. As the electrical activity monitored by EEG originates in neurons in the underlying brain tissue, the recordings made by the electrodes on the surface of the scalp vary in accordance with their orientation ...
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Bipolar Disorder
Bipolar disorder, previously known as manic depression, is a mental disorder characterized by periods of depression and periods of abnormally elevated mood that last from days to weeks each. If the elevated mood is severe or associated with psychosis, it is called mania; if it is less severe, it is called hypomania. During mania, an individual behaves or feels abnormally energetic, happy or irritable, and they often make impulsive decisions with little regard for the consequences. There is usually also a reduced need for sleep during manic phases. During periods of depression, the individual may experience crying and have a negative outlook on life and poor eye contact with others. The risk of suicide is high; over a period of 20 years, 6% of those with bipolar disorder died by suicide, while 30–40% engaged in self-harm. Other mental health issues, such as anxiety disorders and substance use disorders, are commonly associated with bipolar disorder. While the causes of this ...
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Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to generate images of the organs in the body. MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from CT and PET scans. MRI is a medical application of nuclear magnetic resonance (NMR) which can also be used for imaging in other NMR applications, such as NMR spectroscopy. MRI is widely used in hospitals and clinics for medical diagnosis, staging and follow-up of disease. Compared to CT, MRI provides better contrast in images of soft-tissues, e.g. in the brain or abdomen. However, it may be perceived as less comfortable by patients, due to the usually longer and louder measurements with the subject in a long, confining tube, though "Open" MRI designs mostly relieve this. Additionally, implants and ...
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The New York Post
The ''New York Post'' (''NY Post'') is a conservative daily tabloid newspaper published in New York City. The ''Post'' also operates NYPost.com, the celebrity gossip site PageSix.com, and the entertainment site Decider.com. It was established in 1801 by Federalist and Founding Father Alexander Hamilton, and became a respected broadsheet in the 19th century under the name ''New York Evening Post''. Its most famous 19th-century editor was William Cullen Bryant. In the mid-20th century, the paper was owned by Dorothy Schiff, a devoted liberal, who developed its tabloid format. In 1976, Rupert Murdoch bought the ''Post'' for US$30.5 million. Since 1993, the ''Post'' has been owned by Murdoch's News Corp. Its distribution ranked 4th in the US in 2019. History 19th century The ''Post'' was founded by Alexander Hamilton with about US$10,000 () from a group of investors in the autumn of 1801 as the ''New-York Evening Post'', a broadsheet. Hamilton's co-investors included other N ...
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British Columbia
British Columbia (commonly abbreviated as BC) is the westernmost province of Canada, situated between the Pacific Ocean and the Rocky Mountains. It has a diverse geography, with rugged landscapes that include rocky coastlines, sandy beaches, forests, lakes, mountains, inland deserts and grassy plains, and borders the province of Alberta to the east and the Yukon and Northwest Territories to the north. With an estimated population of 5.3million as of 2022, it is Canada's third-most populous province. The capital of British Columbia is Victoria and its largest city is Vancouver. Vancouver is the third-largest metropolitan area in Canada; the 2021 census recorded 2.6million people in Metro Vancouver. The first known human inhabitants of the area settled in British Columbia at least 10,000 years ago. Such groups include the Coast Salish, Tsilhqotʼin, and Haida peoples, among many others. One of the earliest British settlements in the area was Fort Victoria, established ...
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Vancouver
Vancouver ( ) is a major city in western Canada, located in the Lower Mainland region of British Columbia. As the List of cities in British Columbia, most populous city in the province, the 2021 Canadian census recorded 662,248 people in the city, up from 631,486 in 2016. The Greater Vancouver, Greater Vancouver area had a population of 2.6million in 2021, making it the List of census metropolitan areas and agglomerations in Canada#List, third-largest metropolitan area in Canada. Greater Vancouver, along with the Fraser Valley Regional District, Fraser Valley, comprises the Lower Mainland with a regional population of over 3 million. Vancouver has the highest population density in Canada, with over 5,700 people per square kilometre, and fourth highest in North America (after New York City, San Francisco, and Mexico City). Vancouver is one of the most Ethnic origins of people in Canada, ethnically and Languages of Canada, linguistically diverse cities in Canada: 49.3 percent of ...
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Principal Photography
Principal photography is the phase of producing a film or television show in which the bulk of shooting takes place, as distinct from the phases of pre-production and post-production. Personnel Besides the main film personnel, such as actors, director, cinematographer or sound engineer and their respective assistants ( assistant director, camera assistant, boom operator), the unit production manager plays a decisive role in principal photography. They are responsible for the daily implementation of the shoot, managing the daily call sheet, the location barriers, transportation, and catering. In addition, there are numerous roles that serve the organization and the orderly sequence of the production, such as grips or gaffers. Other roles are related with the preparation of a daily production report, which shows the progress of the production compared to the schedule and contains further reports. This includes the storyboard with instructions for the copier and the ...
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