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Angelica Gigas
''Angelica gigas'', also called Korean angelica, giant angelica, purple parsnip, and dangquai, is a monocarpic biennial or short lived perennial plant from Korea and China. It inhabits forests, grasslands and banks of streams. The roots are used in traditional Chinese medicine. Description ''Angelica gigas'' is a stout plant that is 1 to 2 meters high with deep thick roots and a purplish, ribbed stem. It has deeply dissected, very big, broad, pointy leaves. The plant is a biennial that flowers in the months of July to August in dark purple umbels and selfseeds abundantly when the seeds have ripened. Cultivation Giant angelica prefers moist soil and full sun or semishade. The plant is best propagated through seeds in the spring or through transplantation of selfseeded seedlings. Chemical components Research in 2007 has isolated a chemical from the root of the plant, a coumarin derivative called decursin, that may have anti-androgenic properties ''in vitro''. In 2013, the mai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Korea National Arboretum
Korea National Arboretum () is an over-500-year-old arboretum located in Pocheon city of Gyeonggi Province of South Korea. It is widely known as "Gwangneung Forest ()" by the public. It is designated as UNESCO World Network of Biosphere Reserve and the country's 11th natural monument. Its history can be traced back to Joseon Dynasty. The planting of large forests started during the reign of Sejo of Joseon. He and Queen Jeonghui designated the area for a tomb which later named ''Gwangneung.'' Their tomb is one of Royal Tombs of the Joseon Dynasty, a UNESCO World Heritage Site. Following the construction of the tomb, it and its surrounding areas were designated as royal forest and kept under strict protection which lasted throughout post-Joseon history. The area was devastated during the Korean war {{Infobox military conflict , conflict = Korean War , partof = the Cold War and the Korean conflict , image = Korean War Montage 2.png , ima ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anti-androgen
Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body. They act by blocking the androgen receptor (AR) and/or inhibiting or suppressing androgen production. They can be thought of as the functional opposites of AR agonists, for instance androgens and anabolic steroids (AAS) like testosterone, DHT, and nandrolone and selective androgen receptor modulators (SARMs) like enobosarm. Antiandrogens are one of three types of sex hormone antagonists, the others being antiestrogens and antiprogestogens. Antiandrogens are used to treat an assortment of androgen-dependent conditions. In men, antiandrogens are used in the treatment of prostate cancer, enlarged prostate, scalp hair loss, overly high sex drive, unusual and problematic sexual urges, and early puberty. In women, antiandrogens are used to treat acne, seborrhea, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flora Of China
The flora of China consists of a diverse range of plant species including over 39,000 vascular plants, 27,000 species of fungi and 3000 species of bryophytes.Wu, Z. Y., P. H. Raven & D. Y. Hong, eds. 2006. Flora of China. Vol. 22 (Poaceae). Science Press, Beijing, and Missouri Botanical Garden Press, St. Louis More than 30,000 plant species are native to China, representing nearly one-eighth of the world's total plant species, including thousands found nowhere else on Earth. China's land, extending over 9.6 million km, contains a variety of ecosystems and climates for plants to grow in. Some of the main climates include shores, tropical and subtropical forests, deserts, elevated plateaus and mountains. The events of the continental drift and early Paleozoic Caledonian movement also play a part in creating climatic and geographical diversity resulting in high levels of endemic vascular flora. These landscapes provide different ecosystems and climates for plants to grow in, crea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flora Of Korea
Flora is all the plant life present in a particular region or time, generally the naturally occurring ( indigenous) native plants. Sometimes bacteria and fungi are also referred to as flora, as in the terms ''gut flora'' or ''skin flora''. Etymology The word "flora" comes from the Latin name of Flora, the goddess of plants, flowers, and fertility in Roman mythology. The technical term "flora" is then derived from a metonymy of this goddess at the end of the sixteenth century. It was first used in poetry to denote the natural vegetation of an area, but soon also assumed the meaning of a work cataloguing such vegetation. Moreover, "Flora" was used to refer to the flowers of an artificial garden in the seventeenth century. The distinction between vegetation (the general appearance of a community) and flora (the taxonomic composition of a community) was first made by Jules Thurmann (1849). Prior to this, the two terms were used indiscriminately.Thurmann, J. (1849). ''Essai de Ph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Angelica
''Angelica'' is a genus of about 60 species of tall biennial and perennial herbs in the family Apiaceae, native to temperate and subarctic regions of the Northern Hemisphere, reaching as far north as Iceland, Lapland, and Greenland. They grow to tall, with large bipinnate leaves and large compound umbels of white or greenish-white flowers. Found mainly in China, its main use was for medicine. It shows variations in fruit anatomy, leaf morphology, and subterranean structures. The genes are extremely polymorphic. Some species can be found in purple moor and rush pastures. Characteristics ''Angelica'' species grow to tall, with large bipinnate leaves and large compound umbels of white or greenish-white flowers. Their large, sparkling, starburst flowers are pollinated by a great variety of insects (the generalist pollination syndrome), the floral scents are species-specific, and even specific to particular subspecies. The active ingredients of angelica are found in the r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacokinetic
Pharmacokinetics (from Ancient Greek ''pharmakon'' "drug" and ''kinetikos'' "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism. The substances of interest include any chemical xenobiotic such as: pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models. Overview Pharmacokinetics describes how the body affects a specific xenobiotic/chemical after administration through the mechanisms of absorption and distribution ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Brain Barrier
Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in the circulatory system is also known as ''peripheral blood'', and the blood cells it carries, ''peripheral blood cells''. Blood is composed of blood cells suspended in blood plasma. Plasma, which constitutes 55% of blood fluid, is mostly water (92% by volume), and contains proteins, glucose, mineral ions, hormones, carbon dioxide (plasma being the main medium for excretory product transportation), and blood cells themselves. Albumin is the main protein in plasma, and it functions to regulate the colloidal osmotic pressure of blood. The blood cells are mainly red blood cells (also called RBCs or erythrocytes), white blood cells (also called WBCs or leukocytes) and platelets (also called thrombocytes). The most abundant cells in vertebrate bl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cytochrome P450
Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that functions as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormone synthesis and breakdown. In 1963, Estabrook, Cooper, and Rosenthal described the role of CYP as a catalyst in steroid hormone synthesis and drug metabolism. In plants, these proteins are important for the biosynthesis of defensive compounds, fatty acids, and hormones. CYP enzymes have been identified in all kingdoms of life: animals, plants, fungi, protists, bacteria, and archaea, as well as in viruses. However, they are not omnipresent; for example, they have not been found in ''Escherichia coli''. , more than 300,000 distinct CYP proteins are known. CYPs are, in general, the terminal oxidase enzymes in electron transfer chains, broadly categorized as P450-containing systems. The term "P450" is deriv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epoxide
In organic chemistry, an epoxide is a cyclic ether () with a three-atom ring. This ring approximates an equilateral triangle, which makes it strained, and hence highly reactive, more so than other ethers. They are produced on a large scale for many applications. In general, low molecular weight epoxides are colourless and nonpolar, and often volatile. Nomenclature A compound containing the epoxide functional group can be called an epoxy, epoxide, oxirane, and ethoxyline. Simple epoxides are often referred to as oxides. Thus, the epoxide of ethylene (C2H4) is ethylene oxide (C2H4O). Many compounds have trivial names; for instance, ethylene oxide is called "oxirane". Some names emphasize the presence of the epoxide functional group, as in the compound ''1,2-epoxyheptane'', which can also be called ''1,2-heptene oxide''. A polymer formed from epoxide precursors is called an ''epoxy'', but such materials do not contain epoxide groups (or contain only a few residual epoxy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isomer
In chemistry, isomers are molecules or polyatomic ions with identical molecular formulae – that is, same number of atoms of each element – but distinct arrangements of atoms in space. Isomerism is existence or possibility of isomers. Isomers do not necessarily share similar chemical or physical properties. Two main forms of isomerism are structural or constitutional isomerism, in which ''bonds'' between the atoms differ; and stereoisomerism or spatial isomerism, in which the bonds are the same but the ''relative positions'' of the atoms differ. Isomeric relationships form a hierarchy. Two chemicals might be the same constitutional isomer, but upon deeper analysis be stereoisomers of each other. Two molecules that are the same stereoisomer as each other might be in different conformational forms or be different isotopologues. The depth of analysis depends on the field of study or the chemical and physical properties of interest. The English word "isomer" () is a back ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Vitro
''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called " test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, '' in vivo'' studies are those conducted in living organisms, including humans, and whole plants. Definition ''In vitro'' ( la, in glass; often not italicized in English usage) studies are conducted using components of an organism that have been isolated ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
