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Adolfo De Bold
Adolfo José de Bold (February 14, 1942October 22, 2021) was an Argentinian-Canadian cardiovascular researcher, best known for his discovery of atrial natriuretic peptide (ANP), a polypeptide hormone secreted by heart muscle cells. The hormone plays a role in regulating blood pressure, blood volume, and cardiovascular growth, and its discovery proved the endocrine function of the heart. De Bold was an officer of the Order of Canada and was an inductee into the Canadian Medical Hall of Fame. Early life De Bold was born Adolfo José de Bold on February 14, 1942, to Ana Patriarca and Adolfo Guillermo de Bold in Paraná, Entre Ríos in eastern Argentina. His mother was a homemaker and his father was a bureaucrat. Before moving to Canada in 1968, De Bold obtained his Bachelor of Science degree in clinical biochemistry at the faculty of chemical sciences of the National University of Córdoba. His move to Canada was prompted by a dissatisfaction with the Argentine scientific fac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paraná, Entre Ríos
Paraná () is the capital city of the Argentine province Entre Ríos, located on the eastern shore of the Paraná River, opposite the city of Santa Fe, capital of the neighbouring Santa Fe Province. The city has a population of 247,863 (). History During the 16th century, inhabitants of the city of Santa Fe settled at the other shore of the Paraná river. The first settlers called it “''Baxada del Paraná''”. Between 1854 and 1861 it was the capital city of the Argentine Confederation. Economy Paraná is not only the head of the provincial government, but also an important river port for the transshipment of cereals, cattle, fish, and lumber from the surrounding region. The principal industries installed are the manufacture of cement, furniture, and ceramics. Cityscape The centre of the city gathers colonial churches, European styles such as that of the ''3 de Febrero'' Theatre or the Government House, the mixed styles of the city's Cathedral, and modern towers like those ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endocrine Gland
Endocrine glands are ductless glands of the endocrine system that secrete their products, hormones, directly into the blood. The major glands of the endocrine system include the pineal gland, pituitary gland, pancreas, ovaries, testes, thyroid gland, parathyroid gland, hypothalamus and adrenal glands. The hypothalamus and pituitary glands are neuroendocrine organs. Pituitary gland The pituitary gland hangs from the base of the brain by the pituitary stalk, and is enclosed by bone. It consists of a hormone-producing glandular portion of the anterior pituitary and a neural portion of the posterior pituitary, which is an extension of the hypothalamus. The hypothalamus regulates the hormonal output of the anterior pituitary and creates two hormones that it exports to the posterior pituitary for storage and later release. Four of the six anterior pituitary hormones are tropic hormones that regulate the function of other endocrine organs. Most anterior pituitary horm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society Of Hypertension
The American Society of Hypertension (abbreviated ASH) was an American non-profit professional society dedicated to advancing research on hypertension and related cardiovascular diseases. History The ASH was founded in 1985 by 17 scientists and physicians. In 2005, the ASH cut ties with the ''American Journal of Hypertension'' over a dispute over control of content published in the ''Journal''. In 2006, the society became the center of a dispute over the appropriate role of pharmaceutical industry in medical research. The dispute prompted several members of an ASH group convened to write a new definition of high blood pressure to resign from the group; those resigning included former ASH president Michael H. Alderman. In 2017, the society dissolved and merged with the American Heart Association The American Heart Association (AHA) is a nonprofit organization in the United States that funds cardiovascular medical research, educates consumers on healthy living and fosters appropriat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Heart Association
The American Heart Association (AHA) is a nonprofit organization in the United States that funds cardiovascular medical research, educates consumers on healthy living and fosters appropriate cardiac care in an effort to reduce disability and deaths caused by cardiovascular disease and stroke. Originally formed in New York City in 1924, it is currently headquartered in Dallas, Texas. The American Heart Association is a national voluntary health agency. They are known for publishinguidelineson cardiovascular disease and prevention, standards on basic life support, advanced cardiac life support (ACLS), and pediatric advanced life support (PALS), and in 2014 issued its first guidelines for preventing strokes in women. They are known also for operating a number of highly visible public service campaigns starting in the 1970s, and also operate a number of fundraising events. In 1994, the '' Chronicle of Philanthropy'', an industry publication, released a study that showed the Americ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Society Of Hypertension
International is an adjective (also used as a noun) meaning "between nations". International may also refer to: Music Albums * ''International'' (Kevin Michael album), 2011 * ''International'' (New Order album), 2002 * ''International'' (The Three Degrees album), 1975 *''International'', 2018 album by L'Algérino Songs * The Internationale, the left-wing anthem * "International" (Chase & Status song), 2014 * "International", by Adventures in Stereo from ''Monomania'', 2000 * "International", by Brass Construction from ''Renegades'', 1984 * "International", by Thomas Leer from ''The Scale of Ten'', 1985 * "International", by Kevin Michael from ''International'' (Kevin Michael album), 2011 * "International", by McGuinness Flint from ''McGuinness Flint'', 1970 * "International", by Orchestral Manoeuvres in the Dark from '' Dazzle Ships'', 1983 * "International (Serious)", by Estelle from '' All of Me'', 2012 Politics * Political international, any transnational organization of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society Of Canada
The Royal Society of Canada (RSC; french: Société royale du Canada, SRC), also known as the Academies of Arts, Humanities and Sciences of Canada (French: ''Académies des arts, des lettres et des sciences du Canada''), is the senior national, bilingual council of distinguished Canadian scholars, humanists, scientists and artists. The primary objective of the RSC is to promote learning and research in the arts, the humanities and the sciences. The RSC is Canada's National Academy and exists to promote Canadian research and scholarly accomplishment in both official languages, to recognize academic and artistic excellence, and to advise governments, non-governmental organizations and Canadians on matters of public interest. History In the late 1870s, the Governor General of Canada, the Marquis of Lorne, determined that Canada required a cultural institution to promote national scientific research and development. Since that time, succeeding Governor Generals have remained involved w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Manning Innovation Awards
The Manning Innovation Awards are awarded by the Ernest C. Manning Awards Foundation to recognize and encourage innovation in Canada. By means of a nomination, Canadian resident citizens, who have demonstrated recent innovative talent in developing and successfully marketing a new concept, process or procedure, may be eligible for a Principal Award ($100,000), Award of Distinction ($25,000), or Innovation Award (2 at $10,000). The Manning Innovation Awards have been granted since 1982. The awards were the idea of David Mitchell, former CEO of Alberta Energy Company (a predecessor of the company now called Encana). The awards are named for former Alberta Premier Ernest Manning. As of 2012, almost 250 people have received Manning Awards and almost $4,500,000 has been awarded Since 1992, the foundation has also handed out the Young Canadian Innovation Awards, honoring exceptional student projects from the Canada-Wide Science Fair.Gwyn Morgan, "Manning Award Laureates on the Cutt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gairdner Foundation International Award
The Canada Gairdner International Award is given annually by the Gairdner Foundation at a special dinner to five individuals for outstanding discoveries or contributions to medical science. Receipt of the Gairdner is traditionally considered a precursor to winning the Nobel Prize in Medicine; as of 2020, 95 Nobel Prizes have been awarded to prior Gairdner recipients. Canada Gairdner International Awards are given annually in the amount of $100,000 (each) payable in Canadian funds and can be awarded to residents of any country in the world. A joint award may be given for the same discovery or contribution to medical science, but in that case each awardee receives a full prize. Past winners *1959 Alfred Blalock, , Harry M. Rose, William D.M. Paton, Eleanor Zaimis, Wilfred G. Bigelow *1960 Joshua Harold Burn, John H. Gibbon Jr., William F. Hamilton, John McMichael, Karl Meyer, Arnold Rice Rich *1961 Russell Brock, Alan C. Burton, Alexander B. Gutman, Jonas H. Kell ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heart Failure
Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome, a group of signs and symptoms caused by an impairment of the heart's blood pumping function. Symptoms typically include shortness of breath, excessive fatigue, and leg swelling. The shortness of breath may occur with exertion or while lying down, and may wake people up during the night. Chest pain, including angina, is not usually caused by heart failure, but may occur if the heart failure was caused by a heart attack. The severity of the heart failure is measured by the severity of symptoms during exercise. Other conditions that may have symptoms similar to heart failure include obesity, kidney failure, liver disease, anemia, and thyroid disease. Common causes of heart failure include coronary artery disease, heart attack, high blood pressure, atrial fibrillation, valvular heart disease, excessive alcohol consumption, infection, and cardiomyopathy. These cause heart failure by alterin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Insulin
Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the ''INS'' gene. It is considered to be the main anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of glucose from the blood into liver, fat and skeletal muscle cells. In these tissues the absorbed glucose is converted into either glycogen via glycogenesis or fats (triglycerides) via lipogenesis, or, in the case of the liver, into both. Glucose production and secretion by the liver is strongly inhibited by high concentrations of insulin in the blood. Circulating insulin also affects the synthesis of proteins in a wide variety of tissues. It is therefore an anabolic hormone, promoting the conversion of small molecules in the blood into large molecules inside the cells. Low insulin levels in the blood have the opposite effect by promoting widespread catabolism, especial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heart Muscle
Cardiac muscle (also called heart muscle, myocardium, cardiomyocytes and cardiac myocytes) is one of three types of vertebrate muscle tissues, with the other two being skeletal muscle and smooth muscle. It is an involuntary, striated muscle that constitutes the main tissue of the wall of the heart. The cardiac muscle (myocardium) forms a thick middle layer between the outer layer of the heart wall (the pericardium) and the inner layer (the endocardium), with blood supplied via the coronary circulation. It is composed of individual cardiac muscle cells joined by intercalated discs, and encased by collagen fibers and other substances that form the extracellular matrix. Cardiac muscle contracts in a similar manner to skeletal muscle, although with some important differences. Electrical stimulation in the form of a cardiac action potential triggers the release of calcium from the cell's internal calcium store, the sarcoplasmic reticulum. The rise in calcium causes the cell's m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Toronto
The University of Toronto (UToronto or U of T) is a public university, public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park (Toronto), Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution of higher learning in Upper Canada. Originally controlled by the Church of England, the university assumed its present name in 1850 upon becoming a secular institution. As a collegiate university, it comprises eleven colleges each with substantial autonomy on financial and institutional affairs and significant differences in character and history. The university maintains three campuses, the oldest of which, St. George, is located in downtown Toronto. The other two satellite campuses are located in University of Toronto Scarborough, Scarborough and University of Toronto Mississauga, Mississauga. The University of Toronto offers over 700 undergraduate and 200 graduate programs. In all major ranking ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
