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Överkalix Study
The Överkalix study () was a study conducted on the physiological effects of various environmental factors on transgenerational epigenetic inheritance. The study was called "''Cardiovascular and diabetes mortality determined by nutrition during parents’ and grandparents’ slow growth period''" and was published in the journal '' European Journal of Human Genetics'' in 2002. The study was conducted utilizing historical records, including harvests and food prices, in Överkalix, a small isolated municipality in northeast Sweden. Mortality risk ratios (RR) on children and grandchildren were determined based on available food supply, as indicated by these historical data. The study started with 320 probands, 164 men and 139 women, born in 1890, 1905, or 1920, and their 1,818 children and grandchildren. 44 were still alive in 1995 when mortality follow-up stopped and other issues (eg. missing birthyear, cause of death unknown) reduced the final analysis to 239 probands. Betwee ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Överkalix Kommun
Överkalix (; ) is a locality and the seat of Överkalix Municipality in Norrbotten County, Sweden with 975 inhabitants in 2010. Climate Överkalix has a subarctic climate with significant temperature differences between the warm short summers and the long and cold winters. Its inland position close to sea level ensures Överkalix is more prone to heatwaves than other areas of Norrbotten. Its July temperatures are also due to the perpetual daylight due to its position just below the Arctic Circle. This results in July days being warmer on average than other European cities as far south as Manchester and Dublin in the British Isles. However, temperatures fall quickly once daylight diminishes, but winters are still less severe than other parts of the world at similar parallels due to mild North Atlantic air somewhat tempering cold extremes. The climate is quite dry for Scandinavia, with average annual precipitation being at . Överkalix Study The Överkalix study () was a study con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Behavioural Genetics
Behavioural genetics, also referred to as behaviour genetics, is a field of scientific research that uses genetic methods to investigate the nature and origins of individual differences in behaviour. While the name "behavioural genetics" connotes a focus on genetic influences, the field broadly investigates the extent to which genetic and environmental factors influence individual differences, and the development of research designs that can remove the confounding of genes and environment. Behavioural genetics was founded as a scientific discipline by Francis Galton in the late 19th century, only to be discredited through association with eugenics movements before and during World War II. In the latter half of the 20th century, the field saw renewed prominence with research on inheritance of behaviour and mental illness in humans (typically using twin and family studies), as well as research on genetically informative model organisms through selective breeding and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dutch Famine Of 1944–45
Dutch or Nederlands commonly refers to: * Something of, from, or related to the Netherlands ** Dutch people as an ethnic group () ** Dutch nationality law, history and regulations of Dutch citizenship () ** Dutch language () * In specific terms, it reflects the Kingdom of the Netherlands ** Dutch Caribbean ** Netherlands Antilles Dutch may also refer to: Places * Dutch, West Virginia, a community in the United States * Pennsylvania Dutch Country People Ethnic groups * Pennsylvania Dutch, a group of early German immigrants to Pennsylvania Specific people * Dutch (nickname), a list of people * Johnny Dutch (born 1989), American hurdler and field athlete * Dutch Schultz (1902–1935), American mobster born Arthur Simon Flegenheimer * Dutch Mantel, ring name of American retired professional wrestler Wayne Maurice Keown (born 1949) * Dutch Savage, ring name of professional wrestler and promoter Frank Stewart (1935–2013) Arts, entertainment, and media Fictional charact ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Maternal
A mother is the female parent of a child. A woman may be considered a mother by virtue of having given birth, by raising a child who may or may not be her biological offspring, or by supplying her ovum for fertilisation in the case of gestational surrogacy. A biological mother is the female genetic contributor to the creation of the infant, through sexual intercourse or egg donation. A biological mother may have legal obligations to a child not raised by her, such as an obligation of monetary support. An adoptive mother is a female who has become the child's parent through the legal process of adoption. A putative mother is a female whose biological relationship to a child is alleged but has not been established. A stepmother is a non-biological female parent married to a child's preexisting parent, and may form a family unit but generally does not have the legal rights and responsibilities of a parent in relation to the child. A father is the male counterpart of a mother. Wom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paternal
A father is the male parent of a child. Besides the paternal bonds of a father to his children, the father may have a parental, legal, and social relationship with the child that carries with it certain rights and obligations. A biological father is the male genetic contributor to the creation of the infant, through sexual intercourse or sperm donation. A biological father may have legal obligations to a child not raised by him, such as an obligation of monetary support. An adoptive father is a man who has become the child's parent through the legal process of adoption. A putative father is a man whose biological relationship to a child is alleged but has not been established. A stepfather is a non-biological male parent married to a child's preexisting parent and may form a family unit but generally does not have the legal rights and responsibilities of a parent in relation to the child. The adjective "paternal" refers to a father and comparatively to "maternal" for a mother. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alleles
An allele is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule. Alleles can differ at a single position through single nucleotide polymorphisms (SNP), but they can also have insertions and deletions of up to several thousand base pairs. Most alleles observed result in little or no change in the function or amount of the gene product(s) they code or regulate for. However, sometimes different alleles can result in different observable phenotypic traits, such as different pigmentation. A notable example of this is Gregor Mendel's discovery that the white and purple flower colors in pea plants were the result of a single gene with two alleles. Nearly all multicellular organisms have two sets of chromosomes at some point in their biological life cycle; that is, they are diploid. For a given locus, if the two chromosomes contain the same allele, they, and the organism, are homozygous with respect to that allele. If the alleles are differ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Embryogenesis
An embryo ( ) is the initial stage of development for a multicellular organism. In organisms that reproduce sexually, embryonic development is the part of the life cycle that begins just after fertilization of the female egg cell by the male sperm cell. The resulting fusion of these two cells produces a single-celled zygote that undergoes many cell divisions that produce cells known as blastomeres. The blastomeres (4-cell stage) are arranged as a solid ball that when reaching a certain size, called a morula, (16-cell stage) takes in fluid to create a cavity called a blastocoel. The structure is then termed a blastula, or a blastocyst in mammals. The mammalian blastocyst hatches before implantating into the endometrial lining of the womb. Once implanted the embryo will continue its development through the next stages of gastrulation, neurulation, and organogenesis. Gastrulation is the formation of the three germ layers that will form all of the different parts o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ovum
The egg cell or ovum (: ova) is the female reproductive cell, or gamete, in most anisogamous organisms (organisms that reproduce sexually with a larger, female gamete and a smaller, male one). The term is used when the female gamete is not capable of movement (non- motile). If the male gamete (sperm) is capable of movement, the type of sexual reproduction is also classified as oogamous. A nonmotile female gamete formed in the oogonium of some algae, fungi, oomycetes, or bryophytes is an oosphere. When fertilized, the oosphere becomes the oospore. When egg and sperm fuse together during fertilisation, a diploid cell (the zygote) is formed, which rapidly grows into a new organism. History While the non-mammalian animal egg was obvious, the doctrine ''ex ovo omne vivum'' ("every living nimal comes froman egg"), associated with William Harvey (1578–1657), was a rejection of spontaneous generation and preformationism as well as a bold assumption that mammals also reproduced v ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sperm
Sperm (: sperm or sperms) is the male reproductive Cell (biology), cell, or gamete, in anisogamous forms of sexual reproduction (forms in which there is a larger, female reproductive cell and a smaller, male one). Animals produce motile sperm with a tail known as a flagellum, which are known as spermatozoa, while some red algae and fungi produce non-motile sperm cells, known as spermatia. Flowering plants contain non-motile sperm inside pollen, while some more basal plants like ferns and some gymnosperms have motile sperm. Sperm cells form during the process known as spermatogenesis, which in amniotes (reptiles and mammals) takes place in the seminiferous tubules of the testicles. This process involves the production of several successive sperm cell precursors, starting with spermatogonia, which Cellular differentiation, differentiate into spermatocytes. The spermatocytes then undergo meiosis, reducing their Ploidy, chromosome number by half, which produces spermatids. The sper ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homology (biology)
In biology, homology is similarity in anatomical structures or genes between organisms of different taxa due to shared ancestry, ''regardless'' of current functional differences. Evolutionary biology explains homologous structures as retained heredity from a common descent, common ancestor after having been subjected to adaptation (biology), adaptive modifications for different purposes as the result of natural selection. The term was first applied to biology in a non-evolutionary context by the anatomist Richard Owen in 1843. Homology was later explained by Charles Darwin's theory of evolution in 1859, but had been observed before this from Aristotle's biology onwards, and it was explicitly analysed by Pierre Belon in 1555. A common example of homologous structures is the forelimbs of vertebrates, where the bat wing development, wings of bats and origin of avian flight, birds, the arms of primates, the front flipper (anatomy), flippers of whales, and the forelegs of quadrupedalis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gametogenesis
Gametogenesis is a biological process by which diploid or haploid precursor cells undergo cell division and differentiation to form mature haploid gametes. Depending on the biological life cycle of the organism, gametogenesis occurs by meiotic division of diploid gametocytes into various gametes, or by mitosis. For example, plants produce gametes through mitosis in gametophytes. The gametophytes grow from haploid spores after sporic meiosis. The existence of a multicellular, haploid phase in the life cycle between meiosis and gametogenesis is also referred to as alternation of generations. It is the biological process of gametogenesis during which cells that are haploid or diploid divide to create other cells. It can take place either through mitotic or meiotic division of diploid gametocytes into different cells depending on an organism's biological life cycle. For instance, gametophytes in plants undergo mitosis to produce gametes. Both male and female have different forms. In ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Replication Timing
Replication timing refers to the order in which segments of DNA along the length of a chromosome are duplicated. DNA replication In eukaryotic cells (cells that package their DNA within a nucleus), chromosomes consist of very long linear double-stranded DNA molecules. During the S-phase of each cell cycle (Figure 1), all of the DNA in a cell is duplicated in order to provide one copy to each of the daughter cells after the next cell division. The process of duplicating DNA is called DNA replication, and it takes place by first unwinding the duplex DNA molecule, starting at many locations called DNA replication origins, followed by an unzipping process that unwinds the DNA as it is being copied. However, replication does not start at all the different origins at once. Rather, there is a defined temporal order in which these origins fire. Frequently a few adjacent origins open up to duplicate a segment of a chromosome, followed some time later by another group of origins opening u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
